MX2020001357A - Microbial production of fatty amines. - Google Patents

Microbial production of fatty amines.

Info

Publication number
MX2020001357A
MX2020001357A MX2020001357A MX2020001357A MX2020001357A MX 2020001357 A MX2020001357 A MX 2020001357A MX 2020001357 A MX2020001357 A MX 2020001357A MX 2020001357 A MX2020001357 A MX 2020001357A MX 2020001357 A MX2020001357 A MX 2020001357A
Authority
MX
Mexico
Prior art keywords
fatty amines
microbial production
host cells
production
employing
Prior art date
Application number
MX2020001357A
Other languages
Spanish (es)
Inventor
G Hom Louis
B Del Cardayre Stephen
Original Assignee
Genomatica Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genomatica Inc filed Critical Genomatica Inc
Publication of MX2020001357A publication Critical patent/MX2020001357A/en

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/001—Amines; Imines
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70—Vectors or expression systems specially adapted for E. coli
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0008—Oxidoreductases (1.) acting on the aldehyde or oxo group of donors (1.2)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0012—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0012—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7)
    • C12N9/0014—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on the CH-NH2 group of donors (1.4)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1096—Transferases (2.) transferring nitrogenous groups (2.6)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1288—Transferases for other substituted phosphate groups (2.7.8)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/93—Ligases (6)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y102/00—Oxidoreductases acting on the aldehyde or oxo group of donors (1.2)
    • C12Y102/01—Oxidoreductases acting on the aldehyde or oxo group of donors (1.2) with NAD+ or NADP+ as acceptor (1.2.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y102/00—Oxidoreductases acting on the aldehyde or oxo group of donors (1.2)
    • C12Y102/01—Oxidoreductases acting on the aldehyde or oxo group of donors (1.2) with NAD+ or NADP+ as acceptor (1.2.1)
    • C12Y102/01042—Hexadecanal dehydrogenase (acylating) (1.2.1.42), i.e. fatty acyl-CoA reductase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y104/00—Oxidoreductases acting on the CH-NH2 group of donors (1.4)
    • C12Y104/09—Oxidoreductases acting on the CH-NH2 group of donors (1.4) with a copper protein as acceptor (1.4.9)
    • C12Y104/09001—Methylamine dehydrogenase (amicyanin) (1.4.9.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y206/00—Transferases transferring nitrogenous groups (2.6)
    • C12Y206/01—Transaminases (2.6.1)
    • C12Y206/01019—4-Aminobutyrate—2-oxoglutarate transaminase (2.6.1.19)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y206/00—Transferases transferring nitrogenous groups (2.6)
    • C12Y206/01—Transaminases (2.6.1)
    • C12Y206/01082—Putrescine aminotransferase (2.6.1.82)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y207/00—Transferases transferring phosphorus-containing groups (2.7)
    • C12Y207/08—Transferases for other substituted phosphate groups (2.7.8)
    • C12Y207/08007—Holo-[acyl-carrier-protein] synthase (2.7.8.7)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y301/00—Hydrolases acting on ester bonds (3.1)
    • C12Y301/02—Thioester hydrolases (3.1.2)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y602/00—Ligases forming carbon-sulfur bonds (6.2)
    • C12Y602/01—Acid-Thiol Ligases (6.2.1)
    • C12Y602/01003—Long-chain-fatty-acid-CoA ligase (6.2.1.3)

Abstract

The disclosure relates to recombinant microorganisms for the production of fatty amines and derivatives thereof. Further contemplated are cultured recombinant host cells as well as methods of producing fatty amines by employing these host cells.
MX2020001357A 2013-12-05 2016-05-31 Microbial production of fatty amines. MX2020001357A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201361912184P 2013-12-05 2013-12-05

Publications (1)

Publication Number Publication Date
MX2020001357A true MX2020001357A (en) 2020-03-20

Family

ID=52350294

Family Applications (2)

Application Number Title Priority Date Filing Date
MX2016007054A MX2016007054A (en) 2013-12-05 2014-12-05 Microbial production of fatty amines.
MX2020001357A MX2020001357A (en) 2013-12-05 2016-05-31 Microbial production of fatty amines.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
MX2016007054A MX2016007054A (en) 2013-12-05 2014-12-05 Microbial production of fatty amines.

Country Status (12)

Country Link
US (2) US10900057B2 (en)
EP (3) EP3647430B1 (en)
JP (3) JP6553610B2 (en)
KR (2) KR102321813B1 (en)
CN (2) CN105874075B (en)
AU (1) AU2014360086B2 (en)
BR (2) BR122020001956B1 (en)
CA (2) CA2932017C (en)
ES (2) ES2932529T3 (en)
MX (2) MX2016007054A (en)
MY (1) MY180645A (en)
WO (1) WO2015085271A1 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111094558A (en) 2017-04-03 2020-05-01 基因组股份公司 Thioesterase variants with improved activity for production of medium-chain fatty acid derivatives
JP2024503868A (en) * 2021-01-17 2024-01-29 ジェノマティカ， インコーポレイテッド Methods and compositions for producing amide compounds
WO2022209763A1 (en) 2021-03-30 2022-10-06 旭化成株式会社 Recombinant polypeptide having carboxylic acid reducing activity
EP4317438A1 (en) 2021-03-30 2024-02-07 Asahi Kasei Kabushiki Kaisha Recombinant polypeptide having acyl-coa compound reducing activity
EP4353814A1 (en) 2021-05-19 2024-04-17 Asahi Kasei Kabushiki Kaisha Recombinant microorganism having diamine producing ability and method for manufacturing diamine
CN114437979B (en) * 2022-02-14 2023-10-24 恒臻(无锡)生物科技有限公司 Arthrobacter capable of degrading erucamide, and acquisition method, culture method and application thereof
WO2023178211A1 (en) 2022-03-16 2023-09-21 Genomatica, Inc. Microorganisms and methods for production of fatty acid derivatives with reduced levels of byproducts

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JPH03219886A (en) 1989-07-20 1991-09-27 Quest Internatl Bv Preparation of delta-lactone
US6428767B1 (en) 1995-05-12 2002-08-06 E. I. Du Pont De Nemours And Company Method for identifying the source of carbon in 1,3-propanediol
PT1766023E (en) 2004-06-04 2010-12-09 Fluxome Sciences As Metabolically engineered cells for the production of polyunsaturated fatty acids
KR101524398B1 (en) 2006-03-15 2015-06-04 디에스엠 아이피 어셋츠 비.브이. Polyunsaturated Fatty Acid Production in Heterologous Organisms Using PUFA Polyketide Synthase Systems
US8110670B2 (en) 2006-05-19 2012-02-07 Ls9, Inc. Enhanced production of fatty acid derivatives
WO2008113041A2 (en) 2007-03-14 2008-09-18 Ls9, Inc. Process for producing low molecular weight hydrocarbons from renewable resources
ES2536405T5 (en) * 2007-03-28 2022-04-06 Genomatica Inc Enhanced production of fatty acid derivatives
WO2009085278A1 (en) 2007-12-21 2009-07-09 Ls9, Inc. Methods and compositions for producing olefins
MX2010012192A (en) 2008-05-16 2011-04-26 Ls9 Inc Methods and compositions for producing hydrocarbons.
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Also Published As

Publication number Publication date
ES2772774T3 (en) 2020-07-08
MX2016007054A (en) 2016-09-06
WO2015085271A1 (en) 2015-06-11
KR20210134820A (en) 2021-11-10
EP3077526B1 (en) 2019-11-20
JP2016538870A (en) 2016-12-15
AU2014360086A1 (en) 2016-07-14
ES2932529T3 (en) 2023-01-20
KR102321813B1 (en) 2021-11-04
BR122020001956B1 (en) 2023-03-14
US11814660B2 (en) 2023-11-14
CA3114049A1 (en) 2015-06-11
EP4163383A1 (en) 2023-04-12
US20190032097A1 (en) 2019-01-31
JP2019205440A (en) 2019-12-05
CA2932017C (en) 2021-05-25
EP3647430B1 (en) 2022-10-26
BR112016012371A2 (en) 2017-09-26
BR112016012371B1 (en) 2023-03-28
EP3647430A1 (en) 2020-05-06
JP2021177785A (en) 2021-11-18
CA3114049C (en) 2023-06-13
EP3077526A1 (en) 2016-10-12
KR20160095053A (en) 2016-08-10
CN105874075B (en) 2020-10-23
JP6553610B2 (en) 2019-07-31
AU2014360086B2 (en) 2018-04-19
CN105874075A (en) 2016-08-17
JP7152365B2 (en) 2022-10-12
EP3077526B8 (en) 2020-01-08
CA2932017A1 (en) 2015-06-11
US20210164002A1 (en) 2021-06-03
MY180645A (en) 2020-12-04
US10900057B2 (en) 2021-01-26
CN111471723A (en) 2020-07-31

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