MX2019013053A - Composicion que contiene ciclodextrina y busulfan. - Google Patents
Composicion que contiene ciclodextrina y busulfan.Info
- Publication number
- MX2019013053A MX2019013053A MX2019013053A MX2019013053A MX2019013053A MX 2019013053 A MX2019013053 A MX 2019013053A MX 2019013053 A MX2019013053 A MX 2019013053A MX 2019013053 A MX2019013053 A MX 2019013053A MX 2019013053 A MX2019013053 A MX 2019013053A
- Authority
- MX
- Mexico
- Prior art keywords
- busulfan
- composition containing
- containing cyclodextrin
- cyclodextrin
- formulation
- Prior art date
Links
- COVZYZSDYWQREU-UHFFFAOYSA-N Busulfan Chemical compound CS(=O)(=O)OCCCCOS(C)(=O)=O COVZYZSDYWQREU-UHFFFAOYSA-N 0.000 title abstract 4
- 229960002092 busulfan Drugs 0.000 title abstract 4
- 239000000203 mixture Substances 0.000 title abstract 4
- 229920000858 Cyclodextrin Polymers 0.000 title abstract 3
- HFHDHCJBZVLPGP-UHFFFAOYSA-N schardinger α-dextrin Chemical compound O1C(C(C2O)O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC(C(O)C2O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC2C(O)C(O)C1OC2CO HFHDHCJBZVLPGP-UHFFFAOYSA-N 0.000 title abstract 3
- 238000009472 formulation Methods 0.000 abstract 3
- 239000007864 aqueous solution Substances 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/255—Esters, e.g. nitroglycerine, selenocyanates of sulfoxy acids or sulfur analogues thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/716—Glucans
- A61K31/724—Cyclodextrins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/40—Cyclodextrins; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
- A61K47/6949—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
- A61K47/6951—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes using cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Emergency Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Dermatology (AREA)
- Hematology (AREA)
- Oncology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Inorganic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762500970P | 2017-05-03 | 2017-05-03 | |
| PCT/US2018/030728 WO2018204535A1 (en) | 2017-05-03 | 2018-05-02 | Composition containing cyclodextrin and busulfan |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2019013053A true MX2019013053A (es) | 2020-02-07 |
Family
ID=64014433
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2019013053A MX2019013053A (es) | 2017-05-03 | 2018-05-02 | Composicion que contiene ciclodextrina y busulfan. |
| MX2023000348A MX2023000348A (es) | 2017-05-03 | 2019-11-01 | Composicion que contiene ciclodextrina y busulfan. |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2023000348A MX2023000348A (es) | 2017-05-03 | 2019-11-01 | Composicion que contiene ciclodextrina y busulfan. |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US20180318249A1 (cg-RX-API-DMAC7.html) |
| EP (1) | EP3618825A4 (cg-RX-API-DMAC7.html) |
| JP (2) | JP7204670B2 (cg-RX-API-DMAC7.html) |
| KR (1) | KR20190141244A (cg-RX-API-DMAC7.html) |
| CN (1) | CN110831588B (cg-RX-API-DMAC7.html) |
| AU (1) | AU2018263924B2 (cg-RX-API-DMAC7.html) |
| BR (1) | BR112019023074A2 (cg-RX-API-DMAC7.html) |
| CA (1) | CA3062308A1 (cg-RX-API-DMAC7.html) |
| MX (2) | MX2019013053A (cg-RX-API-DMAC7.html) |
| WO (1) | WO2018204535A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109078005B (zh) * | 2018-08-07 | 2021-11-26 | 江苏领航生物科技有限公司 | 一种白消安组合物及其制备方法和应用 |
| CN113679852B (zh) * | 2021-09-13 | 2022-11-15 | 天津师范大学 | 一种水溶性主客体复合物及其制备与应用 |
Family Cites Families (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3426011A (en) | 1967-02-13 | 1969-02-04 | Corn Products Co | Cyclodextrins with anionic properties |
| US4783443A (en) | 1986-03-03 | 1988-11-08 | The University Of Chicago | Amino acyl cephalosporin derivatives |
| KR0166088B1 (ko) | 1990-01-23 | 1999-01-15 | . | 수용해도가 증가된 시클로덱스트린 유도체 및 이의 용도 |
| US5376645A (en) | 1990-01-23 | 1994-12-27 | University Of Kansas | Derivatives of cyclodextrins exhibiting enhanced aqueous solubility and the use thereof |
| EP0710673A3 (en) | 1990-05-21 | 1996-08-07 | Toppan Printing Co Ltd | Cyclodextrin derivatives |
| US5180716A (en) * | 1990-08-01 | 1993-01-19 | The Regents Of The University Of California | Cyclodextrin complexes for neuraxial administration of drugs |
| US5430057A (en) | 1993-09-30 | 1995-07-04 | Board Of Regents, The University Of Texas System | Parenteral busulfan for treatment of malignant disease |
| US5874418A (en) | 1997-05-05 | 1999-02-23 | Cydex, Inc. | Sulfoalkyl ether cyclodextrin based solid pharmaceutical formulations and their use |
| US6046177A (en) | 1997-05-05 | 2000-04-04 | Cydex, Inc. | Sulfoalkyl ether cyclodextrin based controlled release solid pharmaceutical formulations |
| EP0889056B1 (en) | 1997-07-01 | 2006-04-12 | Pfizer Products Inc. | Process for making a cyclodextrin |
| TWI242015B (en) | 1999-11-29 | 2005-10-21 | Akzo Nobel Nv | 6-mercapto-cyclodextrin derivatives: reversal agents for drug-induced neuromuscular block |
| CN1232539C (zh) * | 2002-05-10 | 2005-12-21 | 刘云清 | 有机药物与倍他环糊精衍生物的配合物及其制备方法 |
| JP2006500387A (ja) | 2002-08-15 | 2006-01-05 | 雲清 劉 | 固形ナノ医薬およびその調製方法 |
| AU2003275329B2 (en) | 2002-09-13 | 2008-04-03 | Cydex Pharmaceuticals, Inc. | Capsules containing aqueous fill compositions stabilized with derivatized cyclodextrin |
| KR20060096490A (ko) | 2003-10-31 | 2006-09-11 | 더 유니버시티 오브 캔사스 | 술포알킬 에테르-알킬 에테르 시클로덱스트린 유도체 |
| US20070020196A1 (en) * | 2003-12-31 | 2007-01-25 | Pipkin James D | Inhalant formulation containing sulfoalkyl ether cyclodextrin and corticosteroid prepared from a unit dose suspension |
| ES2364491T5 (es) | 2005-10-26 | 2015-02-19 | Cydex Pharmaceuticals, Inc. | Composiciones de sulfoalquiléter ciclodextrina y métodos de preparación de las mismas |
| US7658913B2 (en) * | 2005-11-28 | 2010-02-09 | Verrow Pharmaceuticals, Inc. | Compositions useful for reducing nephrotoxicity and methods of use thereof |
| JP2009517402A (ja) | 2005-11-28 | 2009-04-30 | ディー． ロウェ，バーノン | 腎毒性の低減に有用な組成物及びその使用方法 |
| CN100411688C (zh) * | 2006-09-12 | 2008-08-20 | 南京师范大学 | 含有环糊精/多烯紫杉醇包合物的药物组合物及其制备方法 |
| WO2008067027A2 (en) * | 2006-10-20 | 2008-06-05 | Icos Corporation | Compositions of chkl inhibitors and cyclodextrin |
| MX357677B (es) * | 2009-05-29 | 2018-07-19 | Cydex Pharmaceuticals Inc | Composiciones inyectables de melfalán que comprenden un derivado de ciclodextrina y métodos de fabricación y uso de las mismas. |
| KR20240119191A (ko) * | 2012-05-08 | 2024-08-06 | 오닉스 세라퓨틱스, 인크. | 펩티드 프로테아좀 억제제 제제화를 위한 사이클로덱스트린 복합체화 방법 |
| CN105726467A (zh) * | 2014-12-09 | 2016-07-06 | 四川科瑞德制药有限公司 | 一种白消安注射液及其制备方法 |
-
2018
- 2018-05-02 JP JP2019560139A patent/JP7204670B2/ja active Active
- 2018-05-02 US US15/969,561 patent/US20180318249A1/en not_active Abandoned
- 2018-05-02 WO PCT/US2018/030728 patent/WO2018204535A1/en not_active Ceased
- 2018-05-02 EP EP18794455.8A patent/EP3618825A4/en active Pending
- 2018-05-02 AU AU2018263924A patent/AU2018263924B2/en active Active
- 2018-05-02 BR BR112019023074A patent/BR112019023074A2/pt active Search and Examination
- 2018-05-02 CN CN201880044721.9A patent/CN110831588B/zh active Active
- 2018-05-02 CA CA3062308A patent/CA3062308A1/en active Pending
- 2018-05-02 KR KR1020197035588A patent/KR20190141244A/ko not_active Ceased
- 2018-05-02 MX MX2019013053A patent/MX2019013053A/es unknown
-
2019
- 2019-11-01 MX MX2023000348A patent/MX2023000348A/es unknown
-
2022
- 2022-09-21 US US17/949,970 patent/US20230255919A1/en not_active Abandoned
- 2022-12-28 JP JP2022212559A patent/JP7597778B2/ja active Active
Also Published As
| Publication number | Publication date |
|---|---|
| RU2019135196A (ru) | 2021-06-03 |
| MX2023000348A (es) | 2023-02-13 |
| WO2018204535A1 (en) | 2018-11-08 |
| US20230255919A1 (en) | 2023-08-17 |
| BR112019023074A2 (pt) | 2020-06-09 |
| EP3618825A1 (en) | 2020-03-11 |
| EP3618825A4 (en) | 2021-01-20 |
| JP7204670B2 (ja) | 2023-01-16 |
| JP2020518608A (ja) | 2020-06-25 |
| US20180318249A1 (en) | 2018-11-08 |
| CN110831588A (zh) | 2020-02-21 |
| AU2018263924A1 (en) | 2019-11-21 |
| JP7597778B2 (ja) | 2024-12-10 |
| JP2023026562A (ja) | 2023-02-24 |
| CN110831588B (zh) | 2023-06-27 |
| CA3062308A1 (en) | 2018-11-08 |
| RU2019135196A3 (cg-RX-API-DMAC7.html) | 2021-07-28 |
| KR20190141244A (ko) | 2019-12-23 |
| AU2018263924B2 (en) | 2024-07-04 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| GEP20247634B (en) | Modulator of cystic fibrosis transmembrane conductance regulator, pharmaceutical compositions, methods of treatment, and process for making the modulator | |
| WO2019125011A3 (ko) | 금속-유기 골격체 및 나노셀룰로오스를 이용한 경피전달용 복합체 | |
| MX2015012414A (es) | Sal de omecamtiv mecarbilo y proceso para preparar la sal. | |
| MD4650B1 (ro) | Derivaţi de chinazolină utilizaţi în tratamentul HIV | |
| EP4309643A3 (en) | Viscosity-reducing excipient compounds for protein formulations | |
| NZ728072A (en) | Modulators of toll-like receptors for the treatment of hiv | |
| MY190243A (en) | Hydroxyacid derivatives, a process for their preparation and pharmaceutical compositions containing them | |
| MX2017004896A (es) | Uso de hexadeca-8, 15-dienal como producto quimico aromatico. | |
| MX2017005575A (es) | Formulacion farmaceutica de anticuerpos anti-tnf alfa. | |
| MY192532A (en) | Liquid pharmaceutical composition | |
| PH12017501486A1 (en) | Nasal powder formulation for treatment of hypoglycemia | |
| EP3342858A4 (en) | ROR1-POSITIVE MESENCHYMAL STEM CELLS AND PREPARATION METHOD THEREOF, PHARMACEUTICAL COMPOSITION CONTAINING SAME, AND PREPARATION METHOD THEREOF, AND METHOD FOR PREVENTING OR TREATING DISEASES USING SAID ROR1 POSITIVE MESENCHYMAL STEM CELLS | |
| WO2016007617A3 (en) | Pharmaceutical compounding kit | |
| EA033444B1 (ru) | Снижение вязкости фармацевтических составов | |
| CL2015002387A1 (es) | Nuevos derivados de pirazol. | |
| MX2016000405A (es) | Metodos y formulaciones que permiten la modulacion de respuestas inmunitarias relacionadas con la administracion de un farmaco biofarmaceutico. | |
| WO2016001905A3 (en) | Stable liquid ready-to-use injectable formulation of bortezomib | |
| EA201691741A1 (ru) | Фармацевтическая композиция | |
| EP3679919A4 (en) | SKIN OR HAIR CLEANSING COMPOSITION WITH AN AQUATIC GELLING AGENT AND PROCESS FOR THE PREPARATION OF AN AQUATIC GELLING AND DETERGENT COMPOSITION | |
| MX2023000348A (es) | Composicion que contiene ciclodextrina y busulfan. | |
| PH12016502544B1 (en) | Pharmaceutical preparation containing entecavir as active ingredient, and preparation method therefor | |
| BR112017022523A2 (pt) | ?formulação para cápsulas de gel, cápsula de gel, e, processo?. | |
| SG11201901617PA (en) | Azole compound ophthalmic preparation | |
| PH12018502139A1 (en) | Phosphaplatin liquid formulations | |
| PH12018501991A1 (en) | Pharmaceutical composition for use in treating fibrosis |