MX2019011692A - Nuevo tratamiento de enfermedades mitocondriales. - Google Patents
Nuevo tratamiento de enfermedades mitocondriales.Info
- Publication number
- MX2019011692A MX2019011692A MX2019011692A MX2019011692A MX2019011692A MX 2019011692 A MX2019011692 A MX 2019011692A MX 2019011692 A MX2019011692 A MX 2019011692A MX 2019011692 A MX2019011692 A MX 2019011692A MX 2019011692 A MX2019011692 A MX 2019011692A
- Authority
- MX
- Mexico
- Prior art keywords
- novel treatment
- mitochondrial diseases
- treatment
- mitochondrial
- diseases
- Prior art date
Links
- 208000012268 mitochondrial disease Diseases 0.000 title abstract 4
- 238000011282 treatment Methods 0.000 title abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000004065 mitochondrial dysfunction Effects 0.000 abstract 1
- 238000011269 treatment regimen Methods 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
- A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
- A61K31/355—Tocopherols, e.g. vitamin E
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/453—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with oxygen as a ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
- A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4462—Non condensed piperidines, e.g. piperocaine only substituted in position 3
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Diabetes (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Psychology (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
La presente invención se refiere a un tratamiento innovador para los trastornos mitocondriales y las enfermedades o afecciones asociadas con la disfunción mitocondrial. En particular, se han establecido dosis efectivas y seguras de compuestos adecuados para el tratamiento de trastornos mitocondriales, que se proporcionan para nuevos regímenes de tratamiento y poblaciones de pacientes.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP17165012 | 2017-04-05 | ||
PCT/EP2017/072172 WO2018184706A1 (en) | 2017-04-05 | 2017-09-05 | Novel treatment of mitochondrial diseases |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2019011692A true MX2019011692A (es) | 2020-02-10 |
Family
ID=58489616
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2019011692A MX2019011692A (es) | 2017-04-05 | 2017-09-05 | Nuevo tratamiento de enfermedades mitocondriales. |
Country Status (8)
Country | Link |
---|---|
US (2) | US11285130B2 (es) |
EP (2) | EP3606522B1 (es) |
KR (1) | KR102660473B1 (es) |
AU (1) | AU2017408066B2 (es) |
CA (1) | CA3058033A1 (es) |
ES (1) | ES2959243T3 (es) |
MX (1) | MX2019011692A (es) |
WO (1) | WO2018184706A1 (es) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA3079483A1 (en) * | 2017-11-22 | 2019-05-31 | Khondrion Ip B.V. | Compounds as mpges-1 inhibitors |
NL2026511B1 (en) * | 2020-09-21 | 2022-05-24 | Sulfateq Bv | Compounds for treatment of heart failure |
NL2031091B1 (en) * | 2022-02-28 | 2023-09-07 | Sulfateq Bv | Chromanol compounds for treatment or prophylaxis of ageing and ageing-associated disorders |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB0204232D0 (en) | 2002-02-22 | 2002-04-10 | Isis Innovation | Assay |
EP3456707B1 (en) * | 2007-11-06 | 2020-04-15 | PTC Therapeutics, Inc. | 4- (p-quinonyl)-2-hydroxybutanamide derivatives for treatment of mitochondrial diseases |
WO2012019032A1 (en) | 2010-08-06 | 2012-02-09 | Ampere Life Sciences, Inc. | Treatment of mitochondrial diseases with vitamin k |
JP6045494B2 (ja) | 2010-08-06 | 2016-12-14 | エジソン ファーマシューティカルズ, インコーポレイテッド | ナフトキノンによるミトコンドリア病の処置 |
LT2872497T (lt) * | 2012-07-12 | 2017-04-25 | Khondrion Ip B.V. | Chromanilo dariniai, skirti mitochondrinių ligų gydymui |
US9388156B2 (en) * | 2012-07-12 | 2016-07-12 | Khondiron IP B.V. | Chromanyl derivatives for treating mitochondrial disease |
EP3359521A1 (en) * | 2015-10-08 | 2018-08-15 | Khondrion Ip B.V. | Novel compounds for treating mitochondrial disease |
KR20200090816A (ko) * | 2017-11-22 | 2020-07-29 | 콘드리온 아이피 비.브이. | 우울증 및 편두통 치료용 신규 화합물 |
CA3079483A1 (en) * | 2017-11-22 | 2019-05-31 | Khondrion Ip B.V. | Compounds as mpges-1 inhibitors |
-
2017
- 2017-09-05 KR KR1020197031354A patent/KR102660473B1/ko active IP Right Grant
- 2017-09-05 EP EP17758900.9A patent/EP3606522B1/en active Active
- 2017-09-05 ES ES17758900T patent/ES2959243T3/es active Active
- 2017-09-05 WO PCT/EP2017/072172 patent/WO2018184706A1/en unknown
- 2017-09-05 AU AU2017408066A patent/AU2017408066B2/en active Active
- 2017-09-05 EP EP23184781.5A patent/EP4241842A3/en active Pending
- 2017-09-05 MX MX2019011692A patent/MX2019011692A/es unknown
- 2017-09-05 US US16/500,437 patent/US11285130B2/en active Active
- 2017-09-05 CA CA3058033A patent/CA3058033A1/en active Pending
-
2022
- 2022-02-16 US US17/672,731 patent/US20220265604A1/en active Pending
Also Published As
Publication number | Publication date |
---|---|
ES2959243T3 (es) | 2024-02-22 |
US11285130B2 (en) | 2022-03-29 |
EP4241842A3 (en) | 2023-11-08 |
EP3606522A1 (en) | 2020-02-12 |
EP3606522B1 (en) | 2023-07-12 |
EP3606522C0 (en) | 2023-07-12 |
AU2017408066A1 (en) | 2019-11-21 |
KR20190133206A (ko) | 2019-12-02 |
AU2017408066B2 (en) | 2023-08-24 |
AU2017408066A2 (en) | 2019-11-21 |
KR102660473B1 (ko) | 2024-04-24 |
CA3058033A1 (en) | 2018-10-11 |
EP4241842A2 (en) | 2023-09-13 |
US20220265604A1 (en) | 2022-08-25 |
WO2018184706A1 (en) | 2018-10-11 |
US20210113520A1 (en) | 2021-04-22 |
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