MX2019004894A - Administración de agente activo de la mucosa. - Google Patents
Administración de agente activo de la mucosa.Info
- Publication number
- MX2019004894A MX2019004894A MX2019004894A MX2019004894A MX2019004894A MX 2019004894 A MX2019004894 A MX 2019004894A MX 2019004894 A MX2019004894 A MX 2019004894A MX 2019004894 A MX2019004894 A MX 2019004894A MX 2019004894 A MX2019004894 A MX 2019004894A
- Authority
- MX
- Mexico
- Prior art keywords
- active agent
- agent delivery
- mucosal
- mucosal active
- composition
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/196—Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
- A61K31/4045—Indole-alkylamines; Amides thereof, e.g. serotonin, melatonin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4178—1,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4402—Non condensed pyridines; Hydrogenated derivatives thereof only substituted in position 2, e.g. pheniramine, bisacodyl
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Endocrinology (AREA)
- Heart & Thoracic Surgery (AREA)
- Gynecology & Obstetrics (AREA)
- Cardiology (AREA)
- Reproductive Health (AREA)
- Hospice & Palliative Care (AREA)
- Otolaryngology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Un método para aumentar la penetración de agentes activos a través de membranas de la mucosa, el método que comprende la etapa de: a) administrar a un sujeto que lo necesita una composición que comprende: i) uno o más hidrótropos en una cantidad total de menos de 15 % en peso de la composición; y ii) un agente activo con un coeficiente de partición (logP) o coeficiente de distribución (logD) de entre 0 y 5.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AU2016904449A AU2016904449A0 (en) | 2016-10-31 | Mucosal Active Agent Delivery | |
PCT/AU2017/051193 WO2018076074A1 (en) | 2016-10-31 | 2017-10-30 | Mucosal active agent delivery |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2019004894A true MX2019004894A (es) | 2019-06-20 |
Family
ID=62023155
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2019004894A MX2019004894A (es) | 2016-10-31 | 2017-10-30 | Administración de agente activo de la mucosa. |
Country Status (10)
Country | Link |
---|---|
US (1) | US11458201B2 (es) |
EP (1) | EP3532068A4 (es) |
JP (1) | JP2019536769A (es) |
KR (1) | KR20190082803A (es) |
CN (1) | CN109996547A (es) |
AU (1) | AU2017351744A1 (es) |
BR (1) | BR112019008565A2 (es) |
CA (1) | CA3041112A1 (es) |
MX (1) | MX2019004894A (es) |
WO (1) | WO2018076074A1 (es) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TWI829687B (zh) * | 2018-05-07 | 2024-01-21 | 丹麥商諾佛 儂迪克股份有限公司 | 包含glp-1促效劑與n-(8-(2-羥基苯甲醯基)胺基)辛酸之鹽的固體組成物 |
Family Cites Families (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH05221857A (ja) * | 1992-02-14 | 1993-08-31 | Arakusu:Kk | 配合解熱鎮痛剤 |
CA2238484A1 (en) * | 1995-11-28 | 1997-06-05 | Michael D. Wider | Antimicrobial composition and methods of use therefor |
US20040136914A1 (en) * | 1997-10-01 | 2004-07-15 | Dugger Harry A. | Buccal, polar and non-polar spray containing ondansetron |
TWI223598B (en) * | 1998-06-22 | 2004-11-11 | Pfizer Ireland Pharmaceuticals | An intranasal pharmaceutical composition for the treatment of male erectile dysfunction or female sexual disorders, an intranasal delivery system or device and sildenafil mesylate |
JP2000119198A (ja) * | 1998-10-16 | 2000-04-25 | Eisai Co Ltd | 苦味等の隠蔽されたホスフォジエステラーゼ阻害剤含有経口製剤 |
JP2002041452A (ja) | 2000-07-27 | 2002-02-08 | Hitachi Ltd | マイクロプロセッサ、半導体モジュール及びデータ処理システム |
ES2223735T3 (es) * | 2000-12-20 | 2005-03-01 | Unilever N.V. | Sistema de limpieza de tejidos. |
US6660211B2 (en) * | 2001-04-23 | 2003-12-09 | Kimberly-Clark Worldwide, Inc. | Methods of making biodegradable films having enhanced ductility and breathability |
US20100204323A1 (en) * | 2004-12-09 | 2010-08-12 | The Dial Corporation | Antimicrobial compositions comprising organic acid esters and methods for reducing virus and bacterial populations using such compositions |
JP5514270B2 (ja) * | 2005-09-13 | 2014-06-04 | ロート製薬株式会社 | アシタザノラスト含有組成物 |
MX2008014905A (es) * | 2006-05-24 | 2009-03-05 | Dial Corp | Composicion y metodo para controlar la transmision de norovirus. |
RU2008152442A (ru) * | 2006-06-05 | 2010-07-20 | Дзей Дайл Корпорейшн (Us) | Способы и изделия, имеющие высокую противовирусную и противобактериальную эффективность |
EP2068831A4 (en) * | 2006-07-28 | 2010-07-21 | Novadel Pharma Inc | ANTIMIGRANEOUS MUNDSPRAY FORMULATIONS AND CORRESPONDING METHODS |
WO2008141264A1 (en) * | 2007-05-10 | 2008-11-20 | Novadel Pharma Inc. | Anti-insomnia compositions and methods |
US20110195042A1 (en) * | 2010-02-10 | 2011-08-11 | Thomas Edward Huetter | Compositions, Methods and Kits Useful for Treating a Respiratory Symptom |
GB201006200D0 (en) * | 2010-04-14 | 2010-06-02 | Ayanda As | Composition |
US20130143894A1 (en) * | 2010-06-07 | 2013-06-06 | vadel Pharma Inc. | Oral spray formulations ad methods for administration of sildenafil |
EP2787967B1 (en) * | 2011-12-05 | 2018-10-31 | Suda Limited | Oral spray formulations and methods for administration of sildenafil |
EP2906547B2 (en) * | 2012-10-12 | 2022-10-26 | L'Oréal | Cosmetic compositions containing at least one hydrotrope and at least one active compound |
US20150250791A1 (en) * | 2014-03-06 | 2015-09-10 | Bhaskara Rao Jasti | Combining sildenafil with caffeine in an oral disintegrating dosage form |
US20160166543A1 (en) * | 2014-12-10 | 2016-06-16 | Hemant N. Joshi | Stable combination oral liquid formulation of melatonin and an antihistaminic agent |
-
2017
- 2017-10-30 WO PCT/AU2017/051193 patent/WO2018076074A1/en unknown
- 2017-10-30 BR BR112019008565A patent/BR112019008565A2/pt not_active IP Right Cessation
- 2017-10-30 KR KR1020197014312A patent/KR20190082803A/ko not_active Application Discontinuation
- 2017-10-30 MX MX2019004894A patent/MX2019004894A/es unknown
- 2017-10-30 AU AU2017351744A patent/AU2017351744A1/en not_active Abandoned
- 2017-10-30 US US16/345,098 patent/US11458201B2/en active Active
- 2017-10-30 EP EP17865329.1A patent/EP3532068A4/en not_active Withdrawn
- 2017-10-30 JP JP2019523864A patent/JP2019536769A/ja active Pending
- 2017-10-30 CN CN201780067280.XA patent/CN109996547A/zh active Pending
- 2017-10-30 CA CA3041112A patent/CA3041112A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
EP3532068A4 (en) | 2020-04-29 |
KR20190082803A (ko) | 2019-07-10 |
US20190282697A1 (en) | 2019-09-19 |
JP2019536769A (ja) | 2019-12-19 |
BR112019008565A2 (pt) | 2019-07-09 |
WO2018076074A1 (en) | 2018-05-03 |
AU2017351744A1 (en) | 2019-05-02 |
EP3532068A1 (en) | 2019-09-04 |
CA3041112A1 (en) | 2018-05-03 |
US11458201B2 (en) | 2022-10-04 |
CN109996547A (zh) | 2019-07-09 |
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