MX2019002607A - Composiciones y metodos para el tratamiento de resistencia a la insulina. - Google Patents

Composiciones y metodos para el tratamiento de resistencia a la insulina.

Info

Publication number
MX2019002607A
MX2019002607A MX2019002607A MX2019002607A MX2019002607A MX 2019002607 A MX2019002607 A MX 2019002607A MX 2019002607 A MX2019002607 A MX 2019002607A MX 2019002607 A MX2019002607 A MX 2019002607A MX 2019002607 A MX2019002607 A MX 2019002607A
Authority
MX
Mexico
Prior art keywords
insulin resistance
treatment
compositions
methods
insulin
Prior art date
Application number
MX2019002607A
Other languages
English (en)
Inventor
Merali Salim
A Barrero Carlos
E Childers Wayne
C Morton George
Original Assignee
Univ Temple
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Temple filed Critical Univ Temple
Publication of MX2019002607A publication Critical patent/MX2019002607A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis

Landscapes

  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Endocrinology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Emergency Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Los compuestos de la formula I, y sales farmaceuticamente efectivas del mismo (Ver fórmula I) en donde R1 - R14, m, n, o, p, q y r son como se definen en la presente, se proporcionan para el tratamiento de incrementar la sensibilidad a la insulina, reducir la resistencia a la insulina, prevenir la resistencia a la insulina y tratar los trastornos de resistencia a la insulina.
MX2019002607A 2016-09-07 2017-09-07 Composiciones y metodos para el tratamiento de resistencia a la insulina. MX2019002607A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201662384390P 2016-09-07 2016-09-07
PCT/US2017/050462 WO2018049019A1 (en) 2016-09-07 2017-09-07 Compositions and methods for treatment of insulin resistance

Publications (1)

Publication Number Publication Date
MX2019002607A true MX2019002607A (es) 2019-09-18

Family

ID=61561578

Family Applications (2)

Application Number Title Priority Date Filing Date
MX2019002607A MX2019002607A (es) 2016-09-07 2017-09-07 Composiciones y metodos para el tratamiento de resistencia a la insulina.
MX2022006229A MX2022006229A (es) 2016-09-07 2019-03-06 Composiciones y metodos para el tratamiento de resistencia a la insulina.

Family Applications After (1)

Application Number Title Priority Date Filing Date
MX2022006229A MX2022006229A (es) 2016-09-07 2019-03-06 Composiciones y metodos para el tratamiento de resistencia a la insulina.

Country Status (10)

Country Link
US (2) US10729670B2 (es)
EP (1) EP3509575A4 (es)
JP (1) JP7235312B2 (es)
CN (1) CN110139644B (es)
AU (2) AU2017324510B2 (es)
BR (1) BR112019004405A2 (es)
CA (1) CA3035972A1 (es)
MX (2) MX2019002607A (es)
WO (1) WO2018049019A1 (es)
ZA (1) ZA201902155B (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2019002607A (es) * 2016-09-07 2019-09-18 Univ Temple Composiciones y metodos para el tratamiento de resistencia a la insulina.
CA3093245A1 (en) * 2018-03-07 2019-09-12 Temple University - Of The Commonwealth System Of Higher Education Compositions and methods for treatment of insulin resistance
RU2020129610A (ru) * 2018-03-07 2022-04-07 Темпл Юниверсити - Оф Зе Коммонвэлс Систем Оф Хайе Эдьюкейшн Композиции и способы для лечения инсулиновой резистентности
TW202206062A (zh) 2020-04-24 2022-02-16 美國坦普大學 高等教育聯邦系統 治療非酒精性脂肪肝炎的方法

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US5073543A (en) 1988-07-21 1991-12-17 G. D. Searle & Co. Controlled release formulations of trophic factors in ganglioside-lipsome vehicle
IT1229203B (it) 1989-03-22 1991-07-25 Bioresearch Spa Impiego di acido 5 metiltetraidrofolico, di acido 5 formiltetraidrofolico e dei loro sali farmaceuticamente accettabili per la preparazione di composizioni farmaceutiche in forma a rilascio controllato attive nella terapia dei disturbi mentali organici e composizioni farmaceutiche relative.
US5120548A (en) 1989-11-07 1992-06-09 Merck & Co., Inc. Swelling modulated polymeric drug delivery device
US5733566A (en) 1990-05-15 1998-03-31 Alkermes Controlled Therapeutics Inc. Ii Controlled release of antiparasitic agents in animals
US5580578A (en) 1992-01-27 1996-12-03 Euro-Celtique, S.A. Controlled release formulations coated with aqueous dispersions of acrylic polymers
US5344846A (en) 1992-12-30 1994-09-06 The United States Of America As Represented By The Department Of Health And Human Services Compositions and methods for inhibiting deoxyhypusine synthase and the growth of cells
US5591767A (en) 1993-01-25 1997-01-07 Pharmetrix Corporation Liquid reservoir transdermal patch for the administration of ketorolac
IT1270594B (it) 1994-07-07 1997-05-07 Recordati Chem Pharm Composizione farmaceutica a rilascio controllato di moguisteina in sospensione liquida
IT1283218B1 (it) * 1996-03-08 1998-04-16 Bracco Spa Polichelanti, loro complessi con ioni metallici, loro preparazione e loro usi
IL140844A0 (en) 2001-01-10 2002-02-10 Polygene Ltd Cationic polysaccharide compositions
US7135575B2 (en) * 2003-03-03 2006-11-14 Array Biopharma, Inc. P38 inhibitors and methods of use thereof
US20080260703A1 (en) 2007-04-23 2008-10-23 Medistem Labortories Treatment of Insulin Resistance and Diabetes
EP2252312B1 (en) 2008-02-07 2014-04-09 Cornell University Methods for preventing or treating insulin resistance
WO2011083150A2 (en) * 2010-01-07 2011-07-14 Akron Molecules Gmbh Obesity small molecules
SG11201401811WA (en) 2011-08-30 2014-09-26 Amc Amsterdam Method for preventing and/or treating insulin resistance
ES2560023T3 (es) 2011-10-18 2016-02-17 Nestec S.A. Composición para su uso para incrementar la sensibilidad a la insulina y / o para reducir la resistencia a la insulina
ES2618374T3 (es) 2012-10-17 2017-06-21 Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College Composiciones y métodos para mejorar la absorción de glucosa
US20150182483A1 (en) * 2014-01-02 2015-07-02 Joel Steven Goldberg Glycation of l-lysine to lower blood glucose and treat complications of diabetes
CN103833623B (zh) 2014-03-03 2016-07-06 河南大学 一种氨基酸-胺缀合物及其制备方法和应用
WO2015161448A1 (en) 2014-04-22 2015-10-29 Wuhan Ll Science And Technology Development Co., Ltd. Ornithine-containing or aspartate-containing compositions and the uses thereof
US10272106B2 (en) * 2014-06-04 2019-04-30 Case Western Reserve University Compositions and methods of treating diabetic retinopathy
EP3347053B1 (en) 2015-09-13 2022-05-25 The Research Foundation For State University Of New York Functional, segregated, charged telodendrimers and nanocarriers and methods of making and using same
US11207285B2 (en) 2016-06-02 2021-12-28 Syndromex Ltd. Diabetes treatment regimens using alpha, alpha-substituted long-chain amphipathic carboxylates
MX2019002607A (es) * 2016-09-07 2019-09-18 Univ Temple Composiciones y metodos para el tratamiento de resistencia a la insulina.
CA3093245A1 (en) 2018-03-07 2019-09-12 Temple University - Of The Commonwealth System Of Higher Education Compositions and methods for treatment of insulin resistance
RU2020129610A (ru) 2018-03-07 2022-04-07 Темпл Юниверсити - Оф Зе Коммонвэлс Систем Оф Хайе Эдьюкейшн Композиции и способы для лечения инсулиновой резистентности
AU2019345297A1 (en) 2018-09-18 2021-04-29 1 Globe Biomedical Co., Ltd. Treatment for non-alcoholic fatty liver disease

Also Published As

Publication number Publication date
CN110139644A (zh) 2019-08-16
JP2019526600A (ja) 2019-09-19
AU2017324510A1 (en) 2019-04-11
AU2017324510B2 (en) 2023-08-31
CN110139644B (zh) 2023-05-23
US10729670B2 (en) 2020-08-04
US20210046030A1 (en) 2021-02-18
US20190192462A1 (en) 2019-06-27
AU2023274183A1 (en) 2023-12-21
CA3035972A1 (en) 2018-03-15
EP3509575A1 (en) 2019-07-17
US11596615B2 (en) 2023-03-07
JP7235312B2 (ja) 2023-03-08
BR112019004405A2 (pt) 2020-06-23
ZA201902155B (en) 2023-12-20
MX2022006229A (es) 2022-06-22
EP3509575A4 (en) 2020-04-22
WO2018049019A1 (en) 2018-03-15

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