MX2019000858A - Cristal y sal de nitroimidazol y metodo de fabricacion de los mismos. - Google Patents

Cristal y sal de nitroimidazol y metodo de fabricacion de los mismos.

Info

Publication number
MX2019000858A
MX2019000858A MX2019000858A MX2019000858A MX2019000858A MX 2019000858 A MX2019000858 A MX 2019000858A MX 2019000858 A MX2019000858 A MX 2019000858A MX 2019000858 A MX2019000858 A MX 2019000858A MX 2019000858 A MX2019000858 A MX 2019000858A
Authority
MX
Mexico
Prior art keywords
salt
manufacturing
nitroimidazole
crystal
crystal form
Prior art date
Application number
MX2019000858A
Other languages
English (en)
Inventor
Z Ding Charles
Huang Zhigang
Luo Wei
Hu Yinghu
Li Zongbin
Lu Qingqing
Original Assignee
Medshine Discovery Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medshine Discovery Inc filed Critical Medshine Discovery Inc
Publication of MX2019000858A publication Critical patent/MX2019000858A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/06—Antibacterial agents for tuberculosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
    • C07C309/01—Sulfonic acids
    • C07C309/02—Sulfonic acids having sulfo groups bound to acyclic carbon atoms
    • C07C309/03—Sulfonic acids having sulfo groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
    • C07C309/04—Sulfonic acids having sulfo groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton containing only one sulfo group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
    • C07C309/01—Sulfonic acids
    • C07C309/28—Sulfonic acids having sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C309/29—Sulfonic acids having sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton of non-condensed six-membered aromatic rings
    • C07C309/30—Sulfonic acids having sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton of non-condensed six-membered aromatic rings of six-membered aromatic rings substituted by alkyl groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

La presente invención describe una forma cristalina y una sal de un compuesto de nitroimidazol, y un método de fabricación del mismo. La invención comprende además una aplicación de la forma cristalina y la sal en la preparación de un producto farmacéutico para prevenir y tratar una infección causada por Mycobacterium tuberculosis u otro microbio. (ver formula).
MX2019000858A 2016-07-22 2017-07-21 Cristal y sal de nitroimidazol y metodo de fabricacion de los mismos. MX2019000858A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN201610587880 2016-07-22
PCT/CN2017/093809 WO2018014863A1 (zh) 2016-07-22 2017-07-21 一种硝基咪唑类化合物的晶型、盐型及其制备方法

Publications (1)

Publication Number Publication Date
MX2019000858A true MX2019000858A (es) 2019-11-11

Family

ID=60992812

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2019000858A MX2019000858A (es) 2016-07-22 2017-07-21 Cristal y sal de nitroimidazol y metodo de fabricacion de los mismos.

Country Status (9)

Country Link
US (1) US20190276475A1 (es)
EP (1) EP3489242A4 (es)
JP (1) JP2019521175A (es)
CN (1) CN109496214B (es)
BR (1) BR112019001163A2 (es)
MX (1) MX2019000858A (es)
RU (1) RU2019104974A (es)
WO (1) WO2018014863A1 (es)
ZA (1) ZA201901120B (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN117384204B (zh) * 2023-10-07 2024-08-23 康龙化成手性医药技术(宁波)有限公司 一种烯醇硅醚类化合物、制备方法及其应用

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI347946B (en) * 2002-10-11 2011-09-01 Otsuka Pharma Co Ltd 2,3-dihydro-6-nitroimidazo[2,1-b]oxazole compound
ZA200602184B (en) * 2003-10-31 2007-10-31 Otsuka Pharma Co Ltd 2,3-dihydro-6-nitroimidazo (2,1-B) oxazole compounds for the treatment of tuberculosis
JP4787529B2 (ja) * 2004-04-09 2011-10-05 大塚製薬株式会社 医薬組成物
CN101544609A (zh) * 2008-03-25 2009-09-30 上海艾力斯医药科技有限公司 4-苯胺喹唑啉衍生物的结晶形式
CA2775961C (en) * 2009-09-30 2017-11-07 Boehringer Ingelheim International Gmbh Method for the preparation of a crystalline form of 1-chloro-4-(beta-d-glucopyranos-1-yl)-2-(4-((s)-tetrahydrofuran-3-yloxy)benzyl)benzene
CN105073740B (zh) * 2014-01-21 2017-06-27 杭州普晒医药科技有限公司 一种化合物的盐及晶型或无定型物、其制备方法、含有它们的药物组合物和用途
CA2955547C (en) * 2014-08-01 2022-08-23 Jiangsu Hansoh Pharmaceutical Group Co., Ltd. Crystalline forms of [1,2,4]triazol0[4,3-a]pyridine derivative and crystalline acid salts thereof and use thereof as c-met inhibitor
BR112017015744A2 (pt) * 2015-01-29 2018-03-13 Medshine Discovery Inc composto apresentando uma estrutura de fórmula (i), um sal farmaceuticamente aceitável do mesmo ou um isômero ótico do mesmo, composição farmacêutica e uso do composto de fórmula (i) para o tratamento e prevenção de mycobacterium tuberculosis ou outras infecções microbianas

Also Published As

Publication number Publication date
RU2019104974A (ru) 2020-08-24
BR112019001163A2 (pt) 2019-04-30
ZA201901120B (en) 2019-12-18
WO2018014863A1 (zh) 2018-01-25
US20190276475A1 (en) 2019-09-12
CN109496214B (zh) 2024-09-10
CN109496214A (zh) 2019-03-19
EP3489242A4 (en) 2020-06-24
EP3489242A1 (en) 2019-05-29
JP2019521175A (ja) 2019-07-25

Similar Documents

Publication Publication Date Title
MX2017016363A (es) Fenoxifenilamidinas sustituidas con halogeno y el uso de estas como fungicidas.
MX2018000050A (es) Fenoxihalogenofenilamidinas y su uso como fungicidas.
SA519402288B1 (ar) مركب بيريميدين واستخداماته الصيدلانية
EP3521477A4 (en) STEEL SHEET FOR CARBONING AND PRODUCTION METHOD FOR STEEL SHEET FOR CARBONING
WO2018039475A8 (en) Use of pridopidine for treating dystonias
EP3640285A4 (en) WATER-SOLUBLE FILM, MEDICAL PACKAGING AND METHOD FOR PRODUCING WATER-SOLUBLE FILM
EP3517648A4 (en) STEEL SHEET FOR CEMENTING AND METHOD FOR PRODUCING STEEL SHEET FOR CEMENTING
EP3470075A4 (en) ANTIMICROBIAL AND ANTIVIRAL DRUG, ANTIMICROBIAL AND ANTIVIRAL ELEMENT, AND METHOD FOR PRODUCING ANTIMICROBIAL AND ANTIVIRAL DRUG
EP3196320A4 (en) Method for manufacturing directional magnetic steel sheet, and nitriding treatment equipment
SA517390475B1 (ar) نظام أكياس متعددة وطريقة لتحضير مكونات الدم
EP3381472A4 (en) MEDICINAL PRODUCTS FOR THE TREATMENT OR PREVENTION OF DISTURBANCES CAUSED BY TGF SIGNALS AND USE THEREOF
EP3633057A4 (en) THICK STEEL PLATE AND METHOD FOR PRODUCING IT
EP3483162B8 (en) N-alkylsulfonyl condensed heterocyclic compound or salt thereof, insecticide containing the compound, and method for using the insecticide
NZ738953A (en) Production method for nitrogen-containing heterocyclic compound, and intermediate of said nitrogen-containing heterocyclic compound
CA3035115C (en) Nitrogenous heterocyclic aromatic compound, preparation method therefor, pharmaceutical composition thereof, and application thereof
EP3636281A4 (en) METHOD OF TREATMENT OF DEPRESSION AND PHARMACEUTICAL COMPOSITION
PH12017501735A1 (en) Novel heterocyclic compound, method for preparing the same, and pharmaceutical composition comprising the same
EP3572392A4 (en) PROCESS FOR THE PRODUCTION OF FLUORENYLIDENEDIALLYLPHENOLS AND FLUORENYLIDENEDIALLYLPHENOLS
FI20165932L (fi) Immunomodulatorisia koostumuksia
PH12016501733A1 (en) Pharmaceutical composition for preventing or treating skin rash
WO2017019951A3 (en) Compositions amd methods of treating acne and photoaging
WO2015095659A3 (en) Indirubin solid dispersion composition
MX2019000858A (es) Cristal y sal de nitroimidazol y metodo de fabricacion de los mismos.
EP3686306A4 (en) STEEL PLATE AND METHOD FOR THE PRODUCTION THEREOF
EP3677687A4 (en) NEW COMPOUND WITH THERAPEUTIC ACTIVITY AGAINST INFECTION WITH MYCOBACTERIUM AVIUM COMPLEX AND PROCESS FOR ITS PRODUCTION