MX2018012192A - Composicion oftalmica estable en almacenamiento. - Google Patents

Composicion oftalmica estable en almacenamiento.

Info

Publication number
MX2018012192A
MX2018012192A MX2018012192A MX2018012192A MX2018012192A MX 2018012192 A MX2018012192 A MX 2018012192A MX 2018012192 A MX2018012192 A MX 2018012192A MX 2018012192 A MX2018012192 A MX 2018012192A MX 2018012192 A MX2018012192 A MX 2018012192A
Authority
MX
Mexico
Prior art keywords
storage
ophthalmic composition
stable ophthalmic
stable
free
Prior art date
Application number
MX2018012192A
Other languages
English (en)
Inventor
BELLMANN Günther
Kröhne Lutz
Original Assignee
Dr Gerhard Mann Chem Pharm Fabrik Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dr Gerhard Mann Chem Pharm Fabrik Gmbh filed Critical Dr Gerhard Mann Chem Pharm Fabrik Gmbh
Publication of MX2018012192A publication Critical patent/MX2018012192A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
    • A61K31/728—Hyaluronic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Ophthalmology & Optometry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Molecular Biology (AREA)
  • Inorganic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

La presente invención se refiere a una composición oftálmica de múltiples fases, estable en almacenamiento, que forma gotas que comprende por lo menos una fase acuosa líquida y por lo menos una fase hidrofóbica líquida, caracterizada en que está libre de emulsionantes y libre de soluciones amortiguadoras y comprende ácido hialurónico y/o hialuronato.
MX2018012192A 2016-04-15 2017-04-12 Composicion oftalmica estable en almacenamiento. MX2018012192A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP16165546.9A EP3231417B1 (de) 2016-04-15 2016-04-15 Lagerungsstabile, ophthalmische zusammensetzung
PCT/EP2017/058825 WO2017178544A1 (de) 2016-04-15 2017-04-12 Lagerungsstabile, ophthalmische zusammensetzung

Publications (1)

Publication Number Publication Date
MX2018012192A true MX2018012192A (es) 2019-02-11

Family

ID=55759507

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2018012192A MX2018012192A (es) 2016-04-15 2017-04-12 Composicion oftalmica estable en almacenamiento.

Country Status (9)

Country Link
US (1) US11413304B2 (es)
EP (1) EP3231417B1 (es)
JP (1) JP7240175B2 (es)
CN (1) CN109069415B (es)
CA (1) CA3018636C (es)
ES (1) ES2704918T3 (es)
MX (1) MX2018012192A (es)
PL (1) PL3231417T3 (es)
WO (1) WO2017178544A1 (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11510924B2 (en) 2017-05-09 2022-11-29 CARDIX Therapeutics, LLC Deuterated pharmaceutical compositions and methods of treating cardiovascular diseases
JOP20190219A1 (ar) 2017-05-09 2019-09-22 Cardix Therapeutics LLC تركيبات صيدلانية وطرق لعلاج أمراض القلب والأوعية الدموية
WO2020055123A1 (ko) * 2018-09-10 2020-03-19 삼성바이오에피스 주식회사 단백질을 포함하는 액상 조성물

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19511322C2 (de) 1995-03-28 1999-09-02 Mann Gerhard Chem Pharm Fab Sterile Augengele mit einem Gehalt an mittelkettigen Triglyceriden und Verfahren zu deren Herstellung
US5814660A (en) * 1995-12-22 1998-09-29 Alcon Laboratories, Inc. 9-oxa prostaglandin analogs as ocular hypotensives
JP5301069B2 (ja) 2004-04-15 2013-09-25 ロート製薬株式会社 アズレン含有水性液剤
AU2005244059A1 (en) * 2004-05-07 2005-11-24 S.K. Pharmaceuticals, Inc. Stabilized hyaluronan preparations and related methods
DE102005035986B4 (de) 2005-07-28 2009-10-15 Bausch & Lomb Incorporated Steriles tropfbares mehrphasiges emulgatorfreies ophthalmisches Präparat
DE102006049091A1 (de) 2006-10-18 2008-04-24 Dr. Gerhard Mann Chem.-Pharm. Fabrik Gmbh Emulgatorfreies ophthalmisches Präparat enthaltend Pflanzenöl
JP5083502B2 (ja) 2006-12-25 2012-11-28 ライオン株式会社 眼科用組成物
DE102009009758A1 (de) * 2009-02-20 2010-08-26 Beiersdorf Ag Hautpflege-Formulierungen mit einem sofort spürbaren Straffungseffekt
US9278132B2 (en) * 2012-02-13 2016-03-08 Bausch & Lomb Incorporated Ophthalmic pharmaceutical compositions and methods of making and using same
EP2630952A1 (en) * 2012-02-23 2013-08-28 Novagali Pharma S.A. Self-preserved oil dispersions comprising boric acid
DE102012221224A1 (de) * 2012-11-20 2014-05-22 Beiersdorf Ag Hydrodispersion mit verbesserter Leistung
JP2014148450A (ja) 2013-02-01 2014-08-21 Hitachi Chemical Co Ltd ルチル型酸化チタンナノロッドの製造方法及びルチル型酸化チタンナノロッド
US9907750B2 (en) 2013-03-19 2018-03-06 Senju Pharmaceutical Co., Ltd. Two-layer separation-type eye drop containing squalane
DE102014202377A1 (de) * 2014-02-10 2015-08-13 Beiersdorf Ag Stabile kosmetische Hydrodispersion
CN104306430B (zh) 2014-10-29 2015-10-28 东莞市达庆医疗器械有限公司 一种医用生物眼部冷疗敷料及其制备方法

Also Published As

Publication number Publication date
CA3018636A1 (en) 2017-10-19
JP2019515882A (ja) 2019-06-13
EP3231417A1 (de) 2017-10-18
JP7240175B2 (ja) 2023-03-15
EP3231417B1 (de) 2018-12-05
WO2017178544A1 (de) 2017-10-19
PL3231417T3 (pl) 2019-05-31
CN109069415B (zh) 2022-04-29
US11413304B2 (en) 2022-08-16
CA3018636C (en) 2021-05-11
CN109069415A (zh) 2018-12-21
US20190111075A1 (en) 2019-04-18
ES2704918T3 (es) 2019-03-20

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FG Grant or registration