MX2018006779A - Terapia ciclica con 3-(5-amino-2-metil-4-oxo-4h-quinazolin-3-il)-p iperidin-2,6-diona. - Google Patents

Terapia ciclica con 3-(5-amino-2-metil-4-oxo-4h-quinazolin-3-il)-p iperidin-2,6-diona.

Info

Publication number
MX2018006779A
MX2018006779A MX2018006779A MX2018006779A MX2018006779A MX 2018006779 A MX2018006779 A MX 2018006779A MX 2018006779 A MX2018006779 A MX 2018006779A MX 2018006779 A MX2018006779 A MX 2018006779A MX 2018006779 A MX2018006779 A MX 2018006779A
Authority
MX
Mexico
Prior art keywords
quinazolin
dione
piperidine
oxo
amino
Prior art date
Application number
MX2018006779A
Other languages
English (en)
Inventor
Gandhi Anita
Hagner Patrick
POURDEHNAD Michael
Original Assignee
Celgene Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Celgene Corp filed Critical Celgene Corp
Publication of MX2018006779A publication Critical patent/MX2018006779A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Abstract

En la presente se proporcionan métodos para tratar, prevenir y/o controlar el cáncer, inclusive linfoma, que comprenden la administración a un paciente de 3-(5-amino-2-metil-4-oxo-4H-quinaz olin-3-il)-piperidin-2,6-diona, o un enantiómero o una mezcla de enantiómeros de este, o una sal, solvato, hidrato, cocristal, clatrato o polimorfo de estos farmacéuticamente aceptables en una pauta de terapia cíclica.
MX2018006779A 2015-12-02 2016-12-01 Terapia ciclica con 3-(5-amino-2-metil-4-oxo-4h-quinazolin-3-il)-p iperidin-2,6-diona. MX2018006779A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201562262263P 2015-12-02 2015-12-02
PCT/US2016/064392 WO2017096024A1 (en) 2015-12-02 2016-12-01 Cycling therapy using 3-(5-amino-2-methyl-4-oxo-4h-quinazolin-3-yl)-piperidine-2,6-dione

Publications (1)

Publication Number Publication Date
MX2018006779A true MX2018006779A (es) 2018-08-01

Family

ID=57614460

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2018006779A MX2018006779A (es) 2015-12-02 2016-12-01 Terapia ciclica con 3-(5-amino-2-metil-4-oxo-4h-quinazolin-3-il)-p iperidin-2,6-diona.

Country Status (13)

Country Link
US (1) US10159675B2 (es)
EP (1) EP3383398A1 (es)
JP (1) JP2018535992A (es)
KR (1) KR20180088401A (es)
AU (1) AU2016364753A1 (es)
BR (1) BR112018010964A2 (es)
CA (1) CA3006758A1 (es)
CL (1) CL2018001434A1 (es)
EA (1) EA201891289A1 (es)
IL (1) IL259597A (es)
MX (1) MX2018006779A (es)
SG (1) SG11201804367PA (es)
WO (1) WO2017096024A1 (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10973822B2 (en) 2015-07-02 2021-04-13 Celgene Corporation Combination therapy for treatment of hematological cancers and solid tumors
WO2018165142A1 (en) * 2017-03-07 2018-09-13 Celgene Corporation Solid forms of 3-(5-amino-2-methyl-4-oxo-4h-quinazolin-3-yl)-piperidine-2,6-dione, and their pharmaceutical compositions and uses
US20220008477A1 (en) 2018-11-08 2022-01-13 Juno Therapeutics, Inc. Methods and combinations for treatment and t cell modulation

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2004526419A (ja) 2000-10-16 2004-09-02 フィロス インク． 抗体模倣物および他の結合タンパク質のためのタンパク質骨格
US7754208B2 (en) 2001-01-17 2010-07-13 Trubion Pharmaceuticals, Inc. Binding domain-immunoglobulin fusion proteins
US20030133939A1 (en) 2001-01-17 2003-07-17 Genecraft, Inc. Binding domain-immunoglobulin fusion proteins
WO2002088171A2 (en) 2001-04-26 2002-11-07 Avidia Research Institute Combinatorial libraries of monomer domains
GB0205395D0 (en) * 2002-03-07 2002-04-24 Univ Southampton Materials and methods relating to the treatment of lymphoma
US7498171B2 (en) 2002-04-12 2009-03-03 Anthrogenesis Corporation Modulation of stem and progenitor cell differentiation, assays, and uses thereof
US7968569B2 (en) 2002-05-17 2011-06-28 Celgene Corporation Methods for treatment of multiple myeloma using 3-(4-amino-1-oxo-1,3-dihydro-isoindol-2-yl)-piperidine-2,6-dione
MX2007005884A (es) 2004-11-16 2008-02-12 Amgen Mountain View Inc Andamios de proteina y usos de los mismos.
DK2420497T3 (en) 2006-09-26 2016-03-07 Celgene Corp 5-substituted quinazolinone derivatives as anticancer agents
CA2829592A1 (en) * 2011-03-11 2012-09-20 Celgene Corporation Methods of treating cancer using 3-(5-amino-2-methyl-4-oxo-4h-quinazolin-3-yl)-piperidine-2,6-dione
MX2013010360A (es) 2011-03-11 2014-04-14 Celgene Corp Formas solidas sde 3-(5-amino-2-metil-4-oxo-4h-quinazolin-3-il)-pi peridin-2,6-diona, y sus composiciones farmaceuticas y usos.
WO2014004990A2 (en) * 2012-06-29 2014-01-03 Celgene Corporation Methods for determining drug efficacy using cereblon-associated proteins
AR099385A1 (es) 2014-01-15 2016-07-20 Celgene Corp Formulaciones de 3-(5-amino-2-metil-4-oxo-4h-quinazolin-3-il)-piperidina-2,6-diona
EP3166635A1 (en) * 2014-07-11 2017-05-17 Celgene Corporation Combination therapy for cancer
US10973822B2 (en) 2015-07-02 2021-04-13 Celgene Corporation Combination therapy for treatment of hematological cancers and solid tumors
EA201890585A1 (ru) 2015-08-27 2018-11-30 Селджин Корпорейшн Составы 3-(5-амино-2-метил-4-оксо-4h-хиназолин-3-ил)пиперидин-2,6-диона

Also Published As

Publication number Publication date
US10159675B2 (en) 2018-12-25
CA3006758A1 (en) 2017-06-08
KR20180088401A (ko) 2018-08-03
EA201891289A1 (ru) 2018-11-30
US20170157123A1 (en) 2017-06-08
CL2018001434A1 (es) 2018-08-31
WO2017096024A1 (en) 2017-06-08
SG11201804367PA (en) 2018-06-28
IL259597A (en) 2018-07-31
AU2016364753A1 (en) 2018-06-14
EP3383398A1 (en) 2018-10-10
JP2018535992A (ja) 2018-12-06
BR112018010964A2 (pt) 2018-12-04

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