MX2017000209A - Composicion de lhrh inmunogenica y uso de la misma en cerdos. - Google Patents

Composicion de lhrh inmunogenica y uso de la misma en cerdos.

Info

Publication number
MX2017000209A
MX2017000209A MX2017000209A MX2017000209A MX2017000209A MX 2017000209 A MX2017000209 A MX 2017000209A MX 2017000209 A MX2017000209 A MX 2017000209A MX 2017000209 A MX2017000209 A MX 2017000209A MX 2017000209 A MX2017000209 A MX 2017000209A
Authority
MX
Mexico
Prior art keywords
peptide
pigs
seq
castrating
vaccine composition
Prior art date
Application number
MX2017000209A
Other languages
English (en)
Inventor
Yi Wang Chang
Jiun Peng Wen-
Original Assignee
United Biomedical Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by United Biomedical Inc filed Critical United Biomedical Inc
Publication of MX2017000209A publication Critical patent/MX2017000209A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0006—Contraceptive vaccins; Vaccines against sex hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/23—Luteinising hormone-releasing hormone [LHRH]; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • A61K2039/552—Veterinary vaccine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/70—Multivalent vaccine

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Reproductive Health (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Endocrinology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Una composición vacunal para castrar cerdos, que comprende un inmunógeno peptídico y un vehículo de suministro o adyuvante aceptables desde el punto de vista veterinario, en donde el inmunógeno peptídico comprende (a) un péptido de LHRH de la SEQ ID NO: 1, y (b) por lo menos un epítopo de célula T cooperadora seleccionado del grupo que consiste en las SEQ ID NOs: 2, 3, 4 y 5 y, opcionalmente, un péptido inmunoestimulador de la SEQ ID NO: 6, en donde el péptido de LHRH se enlaza en forma covalente a través de su residuo de extremo N terminal al epítopo de célula T cooperadora o péptido inmunoestimulador. También se da a conocer un método para castrar o inhibir las características, incluyendo olor a verraco, inducidas por la maduración sexual de los cerdos al utilizar la composición vacunal.
MX2017000209A 2014-07-25 2014-07-25 Composicion de lhrh inmunogenica y uso de la misma en cerdos. MX2017000209A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US2014/048164 WO2016014071A1 (en) 2014-07-25 2014-07-25 Immunogenic lhrh composition and use thereof in pigs

Publications (1)

Publication Number Publication Date
MX2017000209A true MX2017000209A (es) 2017-05-01

Family

ID=55163454

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2017000209A MX2017000209A (es) 2014-07-25 2014-07-25 Composicion de lhrh inmunogenica y uso de la misma en cerdos.

Country Status (12)

Country Link
US (2) US20170216418A1 (es)
EP (2) EP3191119A4 (es)
CN (1) CN107073086B (es)
AU (2) AU2014401765A1 (es)
CA (1) CA2956065C (es)
CO (1) CO2017001320A2 (es)
MX (1) MX2017000209A (es)
PE (1) PE20211787A1 (es)
RU (1) RU2745720C2 (es)
TW (1) TWI595884B (es)
UA (1) UA125607C2 (es)
WO (1) WO2016014071A1 (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107703294B (zh) * 2017-10-12 2019-06-04 华派生物工程集团有限公司 一种用于检测鸡血清中cLHRH抗体效价的ELISA方法
CN107449924B (zh) * 2017-10-12 2019-03-19 华派生物工程集团有限公司 一种鸡免疫去势效果的判定方法
CN107880135A (zh) * 2017-11-17 2018-04-06 华派生物工程集团有限公司 一种鸡促黄体素释放激素重组抗原去势疫苗及其制备方法
AU2019200941B2 (en) * 2018-02-12 2021-02-25 Zoetis Services Llc Anti-GnRH vaccine

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL8900726A (nl) * 1989-03-23 1990-10-16 Stichting Centr Diergeneeskund Peptide, immunogene samenstelling en vaccin- of geneesmiddelpreparaat; werkwijze voor het immuniseren van een zoogdier tegen lhrh, en werkwijze voor het verbeteren van de vleeskwaliteit van varkens.
JP3795914B2 (ja) * 1993-04-27 2006-07-12 ユナイテッド・バイオメディカル・インコーポレイテッド ワクチン用免疫原性ｌｈｒｈペプチド構築体および合成普遍免疫刺激器
US5759551A (en) 1993-04-27 1998-06-02 United Biomedical, Inc. Immunogenic LHRH peptide constructs and synthetic universal immune stimulators for vaccines
WO1995011998A1 (en) 1993-10-26 1995-05-04 United Biomedical, Inc. Structured synthetic antigen libraries as diagnostics, vaccines and therapeutics
CN1179181A (zh) * 1995-02-10 1998-04-15 萨斯喀彻温大学 GnRH－白细胞毒素嵌合体
BR9609411A (pt) * 1995-06-07 1999-12-14 Stichting Inst Dierhouderij Peptìdeo, composição, vacina, e, processos para inocular um animal com a vacina, afetar uma ou mais caracterìsticas reprodutivas ou comportamentais de um animal e imunocastrar um porco.
WO1999056771A2 (en) * 1998-05-05 1999-11-11 Biostar Inc. Methods of raising animals for meat production
TWI227241B (en) * 1998-06-20 2005-02-01 United Biomedical Inc IgE-CH3 domain antigen peptide, peptide conjugate containing the same, and pharmaceutical composition for treating allergies containing the peptide conjugate
TWI229679B (en) * 1998-06-20 2005-03-21 United Biomedical Inc Artificial T helper cell epitopes as immune stimulators for synthetic peptide immunogens
US6025468A (en) * 1998-06-20 2000-02-15 United Biomedical, Inc. Artificial T helper cell epitopes as immune stimulators for synthetic peptide immunogens including immunogenic LHRH peptides
US6780969B2 (en) * 2000-12-22 2004-08-24 United Biomedical, Inc. Synthetic peptide composition as immunogens for prevention of urinary tract infection
US8088388B2 (en) * 2002-02-14 2012-01-03 United Biomedical, Inc. Stabilized synthetic immunogen delivery system
KR102126398B1 (ko) * 2011-12-30 2020-06-25 유나이티드 바이오메디칼 인크. 돼지 생식기 호흡기 증후군 (prrs)의 효과적인 제어를 위한 합성 펩티드-기반 마커 백신 및 진단 시스템

Also Published As

Publication number Publication date
PE20211787A1 (es) 2021-09-09
US20200069781A1 (en) 2020-03-05
RU2017105451A3 (es) 2018-08-27
BR112017000354A2 (pt) 2017-11-07
AU2021201950A1 (en) 2021-04-29
AU2014401765A1 (en) 2017-01-12
TWI595884B (zh) 2017-08-21
RU2017105451A (ru) 2018-08-27
CA2956065A1 (en) 2016-01-28
WO2016014071A1 (en) 2016-01-28
US20170216418A1 (en) 2017-08-03
CN107073086B (zh) 2021-07-27
CA2956065C (en) 2021-05-18
UA125607C2 (uk) 2022-05-04
CO2017001320A2 (es) 2017-07-11
EP3191119A4 (en) 2018-01-24
AU2021201950B2 (en) 2024-06-27
TW201603821A (zh) 2016-02-01
RU2745720C2 (ru) 2021-03-31
CN107073086A (zh) 2017-08-18
EP3842067A1 (en) 2021-06-30
EP3191119A1 (en) 2017-07-19

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