MX2016006142A - Dispositivo para los ojos. - Google Patents

Dispositivo para los ojos.

Info

Publication number
MX2016006142A
MX2016006142A MX2016006142A MX2016006142A MX2016006142A MX 2016006142 A MX2016006142 A MX 2016006142A MX 2016006142 A MX2016006142 A MX 2016006142A MX 2016006142 A MX2016006142 A MX 2016006142A MX 2016006142 A MX2016006142 A MX 2016006142A
Authority
MX
Mexico
Prior art keywords
polymeric matrix
polymeric
delivery device
drug delivery
sustained release
Prior art date
Application number
MX2016006142A
Other languages
English (en)
Inventor
Foidart Jean-Michel
Marie Rakic Jean-
Original Assignee
Eyed Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eyed Pharma filed Critical Eyed Pharma
Publication of MX2016006142A publication Critical patent/MX2016006142A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A61K9/0051—Ocular inserts, ocular implants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/0008—Introducing ophthalmic products into the ocular cavity or retaining products therein
    • A61F9/0017—Introducing ophthalmic products into the ocular cavity or retaining products therein implantable in, or in contact with, the eye, e.g. ocular inserts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0092—Hollow drug-filled fibres, tubes of the core-shell type, coated fibres, coated rods, microtubules or nanotubes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2240/00—Manufacturing or designing of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2240/001—Designing or manufacturing processes
    • A61F2240/005—Templates

Abstract

La invención proporciona un dispositivo intraocular de suministro de fármacos de liberación sostenida, que comprende: (a) un núcleo de matriz polimérica en el que se mezcla al menos un agente terapéutico, y; (b) un revestimiento polimérico que rodea completamente dicho material de matriz polimérica; en donde dicho núcleo de matriz polimérica y el revestimiento polimérico son insolubles e inertes en los líquidos oculares, y en el que dicho dispositivo intraocular de suministro de fármacos de liberación sostenida se forma de un segmento anular compatible y se inserta en el surco del ojo intacto y pseudofáquico.
MX2016006142A 2013-11-14 2014-11-14 Dispositivo para los ojos. MX2016006142A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP13192889 2013-11-14
PCT/EP2014/074644 WO2015071427A1 (en) 2013-11-14 2014-11-14 Eye device

Publications (1)

Publication Number Publication Date
MX2016006142A true MX2016006142A (es) 2016-12-09

Family

ID=49584627

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2016006142A MX2016006142A (es) 2013-11-14 2014-11-14 Dispositivo para los ojos.

Country Status (17)

Country Link
US (1) US9999595B2 (es)
EP (2) EP3566693B1 (es)
JP (1) JP6602761B2 (es)
KR (1) KR20160085870A (es)
CN (1) CN105792812B (es)
AU (1) AU2014350095B9 (es)
BR (1) BR112016010638B1 (es)
CA (1) CA2929684C (es)
CL (1) CL2016001160A1 (es)
EA (1) EA032183B1 (es)
ES (2) ES2740352T3 (es)
HK (1) HK1223271A1 (es)
IL (1) IL245405A0 (es)
MA (1) MA39111A1 (es)
MX (1) MX2016006142A (es)
TN (1) TN2016000162A1 (es)
WO (1) WO2015071427A1 (es)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10507101B2 (en) 2014-10-13 2019-12-17 W. L. Gore & Associates, Inc. Valved conduit
US20160296532A1 (en) 2015-04-13 2016-10-13 Forsight Vision5, Inc. Ocular Insert Composition of a Semi-Crystalline or Crystalline Pharmaceutically Active Agent
US11351058B2 (en) 2017-03-17 2022-06-07 W. L. Gore & Associates, Inc. Glaucoma treatment systems and methods
CN111971026A (zh) 2018-05-24 2020-11-20 塞拉尼斯伊娃高性能聚合物公司 用于持续释放大分子药物化合物的可植入器件
EP3801378A4 (en) 2018-05-24 2022-02-23 Celanese EVA Performance Polymers LLC IMPLANTABLE DEVICE FOR THE DELAYED RELEASE OF A MACROMOLECULAR DRUG COMPOUND
US11298262B2 (en) 2018-07-23 2022-04-12 The Regents Of The University Of Colorado, A Body Corporate Ophthalmic device for drug delivery
US11678983B2 (en) 2018-12-12 2023-06-20 W. L. Gore & Associates, Inc. Implantable component with socket
JP2022538347A (ja) 2019-06-27 2022-09-01 レイヤーバイオ，インコーポレーテッド 眼用デバイス送達方法およびシステム
US11399977B2 (en) 2020-06-04 2022-08-02 SpyGlass Pharma, Inc. Ophthalmic implant system for drug delivery
WO2023091333A1 (en) * 2021-11-17 2023-05-25 Celanese Eva Performance Polymers Llc Implantable device for treating an inflammatory eye condition
CN114224822B (zh) * 2022-01-28 2023-07-14 复旦大学附属眼耳鼻喉科医院 一种眼部缓释给药植入物及其制造方法
EP4233836A1 (en) 2022-02-24 2023-08-30 Eyed Pharma Intraocular drug delivery device comprising an eyelet
WO2024020505A2 (en) * 2022-07-22 2024-01-25 SpyGlass Pharma, Inc. Intraocular drug delivery systems and methods of use

Family Cites Families (25)

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US3416530A (en) 1966-03-02 1968-12-17 Richard A. Ness Eyeball medication dispensing tablet
US3618604A (en) 1969-06-09 1971-11-09 Alza Corp Ocular insert
US3710795A (en) 1970-09-29 1973-01-16 Alza Corp Drug-delivery device with stretched, rate-controlling membrane
US4069307A (en) 1970-10-01 1978-01-17 Alza Corporation Drug-delivery device comprising certain polymeric materials for controlled release of drug
US4014335A (en) 1975-04-21 1977-03-29 Alza Corporation Ocular drug delivery device
US4144317A (en) 1975-05-30 1979-03-13 Alza Corporation Device consisting of copolymer having acetoxy groups for delivering drugs
US4668506A (en) 1985-08-16 1987-05-26 Bausch & Lomb Incorporated Sustained-release formulation containing and amino acid polymer
US4959217A (en) * 1986-05-22 1990-09-25 Syntex (U.S.A.) Inc. Delayed/sustained release of macromolecules
US4718905A (en) * 1986-08-13 1988-01-12 Freeman Jerre M Haptic element using ion beam implantation for an intraocular lens
US4997652A (en) 1987-12-22 1991-03-05 Visionex Biodegradable ocular implants
US5164188A (en) 1989-11-22 1992-11-17 Visionex, Inc. Biodegradable ocular implants
US5178635A (en) 1992-05-04 1993-01-12 Allergan, Inc. Method for determining amount of medication in an implantable device
US5443505A (en) 1993-11-15 1995-08-22 Oculex Pharmaceuticals, Inc. Biocompatible ocular implants
US5773019A (en) * 1995-09-27 1998-06-30 The University Of Kentucky Research Foundation Implantable controlled release device to deliver drugs directly to an internal portion of the body
US5928282A (en) * 1997-06-13 1999-07-27 Bausch & Lomb Surgical, Inc. Intraocular lens
US5902598A (en) * 1997-08-28 1999-05-11 Control Delivery Systems, Inc. Sustained release drug delivery devices
FR2787991B1 (fr) * 1998-12-31 2001-05-25 Medicale De Prec S M P Sa Soc Dispositif pour traiter la presbytie ou autre affection oculaire
CA2473355C (en) * 2002-01-18 2012-01-03 Michael E. Snyder Sustained release ophthalmological device and method of making and using the same
FR2844703B1 (fr) * 2002-09-25 2005-07-08 Alain Nicolas Gilg Dispositif intraoculaire pour restaurer l'accommodation de l'oeil atteint de presbytie
US20090018650A1 (en) * 2003-06-19 2009-01-15 Boxer Wachler Brian S Ophthalmological zonular stretch segment for treating presbyopia
CA2601864A1 (en) * 2005-04-08 2006-10-19 Surmodics, Inc. Sustained release implants and methods for subretinal delivery of bioactive agents to treat or prevent retinal disease
CN102026599A (zh) * 2008-05-12 2011-04-20 犹他大学研究基金会 眼内药物递送装置及相关方法
RU2519193C2 (ru) * 2008-09-12 2014-06-10 Критикал Фармасьютикалс Лимитед Усовершенствование всасывания терапевтических средств через слизистые оболочки или кожу
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CN102905688B (zh) * 2010-04-06 2015-11-25 阿勒根公司 用于前房内药物递送的缓释储库式植入物

Also Published As

Publication number Publication date
IL245405A0 (en) 2016-06-30
CN105792812A (zh) 2016-07-20
EP3068372A1 (en) 2016-09-21
CA2929684A1 (en) 2015-05-21
JP6602761B2 (ja) 2019-11-06
CN105792812B (zh) 2020-10-23
AU2014350095A1 (en) 2016-06-09
WO2015071427A1 (en) 2015-05-21
EP3068372B1 (en) 2019-05-08
US9999595B2 (en) 2018-06-19
EA201690967A1 (ru) 2016-10-31
AU2014350095B9 (en) 2019-09-12
AU2014350095B2 (en) 2019-08-29
BR112016010638B1 (pt) 2023-01-31
EP3566693A1 (en) 2019-11-13
EA032183B1 (ru) 2019-04-30
ES2740352T3 (es) 2020-02-05
MA39111A1 (fr) 2017-04-28
JP2016537370A (ja) 2016-12-01
EP3566693B1 (en) 2021-02-17
KR20160085870A (ko) 2016-07-18
BR112016010638A2 (es) 2017-08-08
ES2864274T3 (es) 2021-10-13
HK1223271A1 (zh) 2017-07-28
TN2016000162A1 (en) 2017-10-06
CA2929684C (en) 2022-02-22
US20160287513A1 (en) 2016-10-06
CL2016001160A1 (es) 2017-03-17

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