MX2016005003A - Marcadores geneticos predictivos de respuesta al acetato de glatiramero. - Google Patents

Marcadores geneticos predictivos de respuesta al acetato de glatiramero.

Info

Publication number
MX2016005003A
MX2016005003A MX2016005003A MX2016005003A MX2016005003A MX 2016005003 A MX2016005003 A MX 2016005003A MX 2016005003 A MX2016005003 A MX 2016005003A MX 2016005003 A MX2016005003 A MX 2016005003A MX 2016005003 A MX2016005003 A MX 2016005003A
Authority
MX
Mexico
Prior art keywords
glatiramer acetate
response
genetic markers
markers predictive
group
Prior art date
Application number
MX2016005003A
Other languages
English (en)
Inventor
Hayden Michael
Hayardeny Liat
Tchelet Amir
James Douglas Ross Colin
Grossman Iris
Ladkani David
Original Assignee
Teva Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Teva Pharma filed Critical Teva Pharma
Publication of MX2016005003A publication Critical patent/MX2016005003A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/02—Peptides of undefined number of amino acids; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Pathology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)

Abstract

La presente invención proporciona un método para tratar un sujeto humano que padece de esclerosis múltiple o un ataque clínico individual consistente con esclerosis múltiple con una composición farmacéutica que comprende acetato de glatirámero y un portador farmacéuticamente aceptable, que comprende los pasos de: (i) determinar un genotipo que corresponde a los polimorfismos de nucleótidos que consisten de: Grupo 1 del sujeto en una ubicación de uno o más (SNPs) individuales seleccionados del grupo.
MX2016005003A 2013-10-21 2014-10-21 Marcadores geneticos predictivos de respuesta al acetato de glatiramero. MX2016005003A (es)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201361893807P 2013-10-21 2013-10-21
US201462048127P 2014-09-09 2014-09-09
US201462048641P 2014-09-10 2014-09-10
PCT/US2014/061647 WO2015061367A1 (en) 2013-10-21 2014-10-21 Genetic markers predictive of response to glatiramer acetate

Publications (1)

Publication Number Publication Date
MX2016005003A true MX2016005003A (es) 2016-08-03

Family

ID=52826364

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2016005003A MX2016005003A (es) 2013-10-21 2014-10-21 Marcadores geneticos predictivos de respuesta al acetato de glatiramero.

Country Status (13)

Country Link
US (2) US9702007B2 (es)
EP (1) EP3060681A4 (es)
JP (1) JP2016540729A (es)
KR (1) KR20160098199A (es)
CN (1) CN105658818A (es)
AU (1) AU2014340247A1 (es)
CA (1) CA2926724A1 (es)
EA (1) EA201690759A1 (es)
IL (1) IL244783A0 (es)
MX (1) MX2016005003A (es)
TW (1) TW201610166A (es)
UY (1) UY35790A (es)
WO (1) WO2015061367A1 (es)

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USRE49251E1 (en) 2010-01-04 2022-10-18 Mapi Pharma Ltd. Depot systems comprising glatiramer or pharmacologically acceptable salt thereof
NZ609938A (en) 2010-10-11 2015-11-27 Teva Pharma Cytokine biomarkers as predictive biomarkers of clinical response for glatiramer acetate
JP2014530819A (ja) 2011-10-10 2014-11-20 テバ ファーマシューティカル インダストリーズ リミティド 酢酸グラチラマーに対する臨床的応答性を予測するために有用な一塩基多形
EP2906719A4 (en) 2012-10-10 2016-11-09 Teva Pharma PREDICTIVE BIOMARKER FOR CLINICAL REACTION FOR GLATIRAMERACETATE
UY35790A (es) 2013-10-21 2015-05-29 Teva Pharma Marcadores genéticos que predicen la respuesta al acetato de glatiramer
US9155775B1 (en) 2015-01-28 2015-10-13 Teva Pharmaceutical Industries, Ltd. Process for manufacturing glatiramer acetate product
CA3050086A1 (en) 2017-03-26 2018-10-04 Mapi Pharma Ltd. Glatiramer depot systems for treating progressive forms of multiple sclerosis
TWI793151B (zh) 2017-08-23 2023-02-21 瑞士商諾華公司 3-(1-氧異吲哚啉-2-基)之氫吡啶-2,6-二酮衍生物及其用途
AR116109A1 (es) 2018-07-10 2021-03-31 Novartis Ag Derivados de 3-(5-amino-1-oxoisoindolin-2-il)piperidina-2,6-diona y usos de los mismos
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CN111088368B (zh) * 2019-12-30 2021-04-16 山西医科大学 一种血液mRNA检测试剂盒及检测方法

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Also Published As

Publication number Publication date
CA2926724A1 (en) 2015-04-30
EP3060681A1 (en) 2016-08-31
IL244783A0 (en) 2016-04-21
JP2016540729A (ja) 2016-12-28
UY35790A (es) 2015-05-29
WO2015061367A1 (en) 2015-04-30
US20150110733A1 (en) 2015-04-23
US9702007B2 (en) 2017-07-11
KR20160098199A (ko) 2016-08-18
US20180002753A1 (en) 2018-01-04
EA201690759A1 (ru) 2017-01-30
EP3060681A4 (en) 2017-06-07
CN105658818A (zh) 2016-06-08
AU2014340247A1 (en) 2016-06-02
TW201610166A (zh) 2016-03-16

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