MX2015015448A - Ensayo de internalizacion del receptor del gusto. - Google Patents

Ensayo de internalizacion del receptor del gusto.

Info

Publication number
MX2015015448A
MX2015015448A MX2015015448A MX2015015448A MX2015015448A MX 2015015448 A MX2015015448 A MX 2015015448A MX 2015015448 A MX2015015448 A MX 2015015448A MX 2015015448 A MX2015015448 A MX 2015015448A MX 2015015448 A MX2015015448 A MX 2015015448A
Authority
MX
Mexico
Prior art keywords
taste receptor
receptor internalization
internalization assay
taste
assay
Prior art date
Application number
MX2015015448A
Other languages
English (en)
Inventor
Yuliya Kurash
Stephen Gravina
Original Assignee
Pepsico Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pepsico Inc filed Critical Pepsico Inc
Publication of MX2015015448A publication Critical patent/MX2015015448A/es

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/566—Immunoassay; Biospecific binding assay; Materials therefor using specific carrier or receptor proteins as ligand binding reagents where possible specific carrier or receptor proteins are classified with their target compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/15—Medicinal preparations ; Physical properties thereof, e.g. dissolubility
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value
    • G01N2500/10—Screening for compounds of potential therapeutic value involving cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Cell Biology (AREA)
  • Organic Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

Esta descripción proporciona un ensayo de internalización del receptor del gusto útil para identificar moduladores del gusto.
MX2015015448A 2013-05-10 2014-05-09 Ensayo de internalizacion del receptor del gusto. MX2015015448A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361821978P 2013-05-10 2013-05-10
PCT/US2014/037507 WO2014183041A1 (en) 2013-05-10 2014-05-09 Taste receptor internalization assay

Publications (1)

Publication Number Publication Date
MX2015015448A true MX2015015448A (es) 2016-03-15

Family

ID=51867771

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2015015448A MX2015015448A (es) 2013-05-10 2014-05-09 Ensayo de internalizacion del receptor del gusto.

Country Status (13)

Country Link
US (1) US9766236B2 (es)
EP (1) EP2994482B1 (es)
JP (1) JP6211685B2 (es)
CN (1) CN105377885B (es)
AU (1) AU2014262540B2 (es)
BR (1) BR112015028082A2 (es)
CA (1) CA2911189A1 (es)
ES (1) ES2776159T3 (es)
HK (1) HK1218302A1 (es)
MX (1) MX2015015448A (es)
PL (1) PL2994482T3 (es)
RU (1) RU2665812C2 (es)
WO (1) WO2014183041A1 (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2994477A4 (en) 2013-05-10 2017-03-22 Pepsico, Inc. Cells as a model to identify potential taste modulators
CA3035784A1 (en) 2016-09-16 2018-03-22 Pepsico, Inc. Compositions and methods for improving taste of non-nutritive sweeteners
BR112023021573A2 (pt) * 2021-05-07 2023-12-19 Firmenich Incorporated Células expressando receptores de sabor amargo e usos das mesmas

Family Cites Families (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4115038A1 (de) * 1991-05-08 1992-11-12 Genentech Inc Neue konjugate, bestehend aus einem glykoprotein und einer nukleinsaeure-bindenden substanz
US6759206B1 (en) * 1997-02-27 2004-07-06 Cellomics, Inc. System for cell-based screening
WO2000003246A2 (en) 1998-07-13 2000-01-20 Cellomics, Inc. A system for cell-based screening
US7402400B2 (en) 2001-07-03 2008-07-22 Regents Of The University Of California Mammalian sweet taste receptors
AU773600B2 (en) * 1999-09-10 2004-05-27 Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The T2R, taste receptor family
US20080244761A1 (en) * 2001-03-07 2008-10-02 Senomyx, Inc. T1r hetero-oligomeric taste receptors and cell lines that express said receptors and use thereof for identification of taste compounds
US6955887B2 (en) 2001-03-30 2005-10-18 Senomyx, Inc. Use of T1R hetero-oligomeric taste receptor to screen for compounds that modulate taste signaling
US7368285B2 (en) * 2001-03-07 2008-05-06 Senomyx, Inc. Heteromeric umami T1R1/T1R3 taste receptors and isolated cells that express same
US7763431B1 (en) * 2001-03-07 2010-07-27 Senomyx, Inc. Binding assays that use the T1R2/T1R3 (sweet) taste receptor to identify compounds that elicit or modulate sweet taste
AU2002336571A1 (en) 2001-09-18 2003-04-01 Irm, Llc Sweet taste receptors
CN1984919A (zh) 2002-07-29 2007-06-20 塞诺米克斯公司 新型苦味受体t2r76的鉴定
AU2003286069A1 (en) 2002-12-18 2004-07-09 Givaudan Sa Chimeric alpha q-gustducin g-proteins
WO2004069191A2 (en) 2003-02-03 2004-08-19 Senomyx Inc. Identification of t1r and t2r modulators
US20050244810A1 (en) 2003-09-29 2005-11-03 Egan Josephine M Taste signaling in gastrointestinal cells
US20050106571A1 (en) 2003-10-02 2005-05-19 The Regents Of The University Of California Mammalian T1R3 sweet taste receptors
WO2006040337A1 (en) * 2004-10-13 2006-04-20 Evotec Technologies Gmbh Method for identifying compounds that affect a transport of a protein through a membrane trafficking pathway
WO2006044594A2 (en) * 2004-10-15 2006-04-27 Monell Chemical Senses Center Methods for culturing mammalian taste cells
US7799538B2 (en) 2005-03-09 2010-09-21 Trustees Of Dartmouth College Method for identifying agents which modulate GTPase activity involved in insulin-stimulated GLUT4 translocation
EP1937718B1 (en) 2005-10-20 2017-12-06 Senomyx, Inc. Chimeric human sweet-umami and umami-sweet taste receptors
WO2007092938A2 (en) 2006-02-08 2007-08-16 Invitrogen Corporation Cellular assays for signaling receptors
KR101356914B1 (ko) 2006-04-20 2014-01-28 지보당 에스아 단맛 강화 방법
EP2035827B1 (en) 2006-06-19 2012-10-17 Givaudan S.A. Nucleic acid, polypeptide and its use
EP2054523B1 (en) * 2006-07-26 2015-11-18 The Coca-Cola Company Methods for identifying modulators of rgs21 activity, compositions comprising an rgs21 modulator, and methods of use thereof to modulate taste sensation
KR20100016044A (ko) * 2007-03-30 2010-02-12 지보당 에스아 조절제의 동정 방법
WO2009008950A2 (en) 2007-06-08 2009-01-15 Senomyx, Inc. Identification of trpml3 (mcoln3) as a salty taste receptor and use in assays for identifying taste (salty) modulators and/or therapeutics that modulate sodium transport, absorption or excretion and/or aldosterone and/or vasopressin production or release
NZ583350A (en) 2007-08-21 2012-03-30 Senomyx Inc Heteroaryl-hydantoin derivatives as bitter taste inhibitors
NZ603996A (en) 2009-02-02 2014-03-28 Chromocell Corp Cells or cell lines that stably express a bitter taste receptor and methods of making them
JP2013512664A (ja) * 2009-12-02 2013-04-18 ユニリーバー・ナームローゼ・ベンノートシヤープ 味覚受容体の潜在的モジュレーター化合物をスクリーニングする改善された方法
CA2824067C (en) * 2011-01-25 2021-02-02 Monell Chemical Senses Center Compositions and methods for providing or modulating sweet taste and methods of screening therefor
WO2013022948A1 (en) * 2011-08-08 2013-02-14 The Coca-Cola Company Cell lines comprising endogenous taste receptors and their uses
EP2994477A4 (en) 2013-05-10 2017-03-22 Pepsico, Inc. Cells as a model to identify potential taste modulators

Also Published As

Publication number Publication date
PL2994482T3 (pl) 2020-06-01
EP2994482A1 (en) 2016-03-16
EP2994482A4 (en) 2016-11-30
WO2014183041A1 (en) 2014-11-13
CN105377885A (zh) 2016-03-02
AU2014262540A1 (en) 2015-11-12
US20160084834A1 (en) 2016-03-24
RU2665812C2 (ru) 2018-09-04
AU2014262540B2 (en) 2016-10-27
RU2015152792A (ru) 2017-06-20
CN105377885B (zh) 2019-11-05
US9766236B2 (en) 2017-09-19
HK1218302A1 (zh) 2017-02-10
CA2911189A1 (en) 2014-11-13
ES2776159T3 (es) 2020-07-29
EP2994482B1 (en) 2020-01-01
JP2016519313A (ja) 2016-06-30
BR112015028082A2 (pt) 2017-07-25
JP6211685B2 (ja) 2017-10-11

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