MX2015015228A - Sobetirome en el tratamiento de enfermedades de mielinizacion. - Google Patents
Sobetirome en el tratamiento de enfermedades de mielinizacion.Info
- Publication number
- MX2015015228A MX2015015228A MX2015015228A MX2015015228A MX2015015228A MX 2015015228 A MX2015015228 A MX 2015015228A MX 2015015228 A MX2015015228 A MX 2015015228A MX 2015015228 A MX2015015228 A MX 2015015228A MX 2015015228 A MX2015015228 A MX 2015015228A
- Authority
- MX
- Mexico
- Prior art keywords
- sobetirome
- treatment
- myelination
- myelination diseases
- diseases
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/14—Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
- A61P5/40—Mineralocorticosteroids, e.g. aldosterone; Drugs increasing or potentiating the activity of mineralocorticosteroids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
Landscapes
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Endocrinology (AREA)
- Neurosurgery (AREA)
- Diabetes (AREA)
- Epidemiology (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Hospice & Palliative Care (AREA)
- Gynecology & Obstetrics (AREA)
- Reproductive Health (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Urology & Nephrology (AREA)
- Psychiatry (AREA)
- Psychology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Peptides Or Proteins (AREA)
- Medicinal Preparation (AREA)
Abstract
Se describen métodos para tratar a un sujeto que tiene o está en riesgo de desarrollar una enfermedad o condición neurodegenerativa asociada con la desmielinización, mielinización insuficiente o subdesarrollo de la vaina de mielina. Los métodos incluyen la administración de una cantidad terapéuticamente efectiva de sobetirome, o una sal farmacéuticamente aceptable del mismo.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201361819467P | 2013-05-03 | 2013-05-03 | |
PCT/US2013/053640 WO2014178892A1 (en) | 2013-05-03 | 2013-08-05 | Use of sobetirome in the treatment of x-linked adrenolenoleukodystrophy |
PCT/US2014/014943 WO2014178931A1 (en) | 2013-05-03 | 2014-02-05 | Sobetirome in the treatment of myelination diseases |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2015015228A true MX2015015228A (es) | 2016-10-03 |
Family
ID=51843844
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2015015228A MX2015015228A (es) | 2013-05-03 | 2014-02-05 | Sobetirome en el tratamiento de enfermedades de mielinizacion. |
MX2021000538A MX2021000538A (es) | 2013-05-03 | 2015-10-30 | Uso de sobetirome en el tratamiento de enfermedades de mielinizacion. |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2021000538A MX2021000538A (es) | 2013-05-03 | 2015-10-30 | Uso de sobetirome en el tratamiento de enfermedades de mielinizacion. |
Country Status (13)
Country | Link |
---|---|
US (3) | US10226438B2 (es) |
EP (1) | EP2991670B8 (es) |
JP (4) | JP2016517883A (es) |
CN (1) | CN105431163A (es) |
AU (1) | AU2014260468A1 (es) |
BR (1) | BR112015027682A2 (es) |
CA (1) | CA2911309A1 (es) |
ES (1) | ES2745532T3 (es) |
HK (1) | HK1222552A1 (es) |
MX (2) | MX2015015228A (es) |
RU (1) | RU2015151216A (es) |
SG (2) | SG11201509012QA (es) |
WO (2) | WO2014178892A1 (es) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2014178892A1 (en) * | 2013-05-03 | 2014-11-06 | Scanlan Thomas S | Use of sobetirome in the treatment of x-linked adrenolenoleukodystrophy |
AU2015253100B2 (en) | 2014-04-30 | 2018-01-18 | The Johns Hopkins University | Dendrimer compositions and their use in treatment of diseases of the eye |
CN115350285A (zh) | 2014-08-13 | 2022-11-18 | 约翰霍普金斯大学 | 树枝状聚合物到脑肿瘤的选择性传递 |
WO2017075580A1 (en) * | 2015-10-29 | 2017-05-04 | The Johns Hopkins University | Compositions and methods for treatment of peroxisomal disorders and leukodystrophies |
EP3445373A4 (en) | 2016-04-22 | 2019-12-18 | Viking Therapeutics, Inc. | USE OF THYROID BETA AGONISTS |
CN110200978B (zh) * | 2016-04-22 | 2023-10-31 | 维京治疗股份有限公司 | 甲状腺β-激动剂的应用 |
JP6982004B2 (ja) | 2016-05-18 | 2021-12-17 | オレゴン ヘルス アンド サイエンス ユニバーシティ | ソベチロム誘導体 |
IL264765B2 (en) * | 2016-08-12 | 2024-03-01 | Univ Oregon Health & Science | Amide compounds, their pharmaceutical preparations and methods of using them |
WO2018183940A1 (en) * | 2017-03-31 | 2018-10-04 | Neurovia, Inc. | Methods and compositions for treating niemann-pick disease |
WO2018201007A2 (en) | 2017-04-27 | 2018-11-01 | The Johns Hopkins University | Dendrimer compositions for use in angiography |
WO2018208707A1 (en) * | 2017-05-08 | 2018-11-15 | Neurovia, Inc. | Methods and compositions for treating demyelinating diseases |
US10780069B2 (en) * | 2017-05-18 | 2020-09-22 | University of Pittsburgh—of the Commonwealth System of Higher Education | Use of GC-1 in transplant related population |
WO2019005816A1 (en) | 2017-06-29 | 2019-01-03 | Yale University | COMPOSITIONS AND METHODS FOR TREATING OR PREVENTING FIBROUS PULMONARY DISEASES |
CA3069567A1 (en) * | 2017-07-18 | 2019-01-24 | Keio University | Anti-bacterial composition against th1 cell-inducing bacteria |
AU2018365250B2 (en) | 2017-11-10 | 2022-05-26 | The Johns Hopkins University | Dendrimer delivery system and methods of use thereof |
US11827596B2 (en) | 2018-12-12 | 2023-11-28 | Autobahn Therapeutics, Inc. | Thyromimetics |
EP3931180A1 (en) | 2019-03-01 | 2022-01-05 | Autobahn Therapeutics, Inc. | Novel thyromimetics |
US11612660B2 (en) | 2019-12-04 | 2023-03-28 | Ashvattha Therapeutics, Inc. | Dendrimer compositions and methods for drug delivery to the eye |
CN111116684B (zh) * | 2019-12-31 | 2020-09-25 | 厦门甘宝利生物医药有限公司 | 一种具有甲状腺激素受体激动剂特性的肝靶向化合物及其药物组合物 |
CN115569233B (zh) * | 2022-10-17 | 2023-07-14 | 湖南大学 | 既能吸光又能与自由基反应的高效光抑制剂的制备方法 |
Family Cites Families (24)
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DE3815221C2 (de) | 1988-05-04 | 1995-06-29 | Gradinger F Hermes Pharma | Verwendung einer Retinol- und/oder Retinsäureester enthaltenden pharmazeutischen Zubereitung zur Inhalation zur Einwirkung auf die Schleimhäute des Tracheo-Bronchialtraktes einschließlich der Lungenalveolen |
ATE344279T1 (de) | 1995-12-13 | 2006-11-15 | Univ California | Kristalle der mit einem ligand komplexierten ligandenbindedomäne des schilddrüsenhormonrezeptors |
KR100405285B1 (ko) | 1996-08-20 | 2003-11-12 | 더 리전트 오브 더 유니버시티 오브 캘리포니아 | 합성 티로이드 호르몬을 포함하는 약제 조성물 |
US5883294A (en) | 1997-06-18 | 1999-03-16 | The Regeants Of The University Of California | Selective thyroid hormone analogs |
JP2002519340A (ja) | 1998-06-30 | 2002-07-02 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | 甲状腺ホルモン類似体およびそれらの調製方法 |
US7560433B2 (en) | 2001-12-21 | 2009-07-14 | Biotempt B.V. | Treatment of multiple sclerosis (MS) |
US7302347B2 (en) | 2002-12-10 | 2007-11-27 | The Regents Of The University Of California | Method for creating specific, high affinity nuclear receptor pharmaceuticals |
US8071134B2 (en) * | 2003-09-15 | 2011-12-06 | Ordway Research Institute, Inc. | Thyroid hormone analogs and methods of use |
AU2004273986B2 (en) * | 2003-09-15 | 2010-04-22 | Nanopharmaceuticals Llc | Thyroid hormone analogs and methods of use in angiogenesis |
WO2006012015A2 (en) | 2004-06-29 | 2006-02-02 | Oregon Health And Science University | Methods and compositions for nerve regeneration |
EP1793814B1 (en) * | 2004-09-15 | 2015-01-21 | NanoPharmaceuticals LLC | Thyroid hormone analogs for inhibiting angiogenesis |
US20090117054A1 (en) | 2005-03-29 | 2009-05-07 | University Of Kentucky Research Foundation | Sublingual spray for the treatment of pain |
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EP2311481A3 (en) | 2006-10-20 | 2013-10-16 | Biogen Idec MA Inc. | Treatment of demyelinating disorders with soluble lymphotoxin-beta-receptor |
WO2008052354A1 (en) | 2006-11-03 | 2008-05-08 | University Of Saskatchewan | Method of treating demyelination diseases |
FI20075245A0 (fi) * | 2007-04-11 | 2007-04-11 | Markku Ahotupa | Menetelmä oksidatiivisen metabolian arvioimiseksi |
US8138201B2 (en) * | 2007-07-11 | 2012-03-20 | Medicinova, Inc. | Treatment of progressive neurodegenerative disease with ibudilast |
WO2009097995A1 (de) * | 2008-02-07 | 2009-08-13 | Sanofi-Aventis | Neue phenyl-substituierte imidazolidine, verfahren zu deren herstellung, diese verbindungen enthaltende arzneimittel und deren verwendung |
KR20190026056A (ko) | 2008-04-21 | 2019-03-12 | 오토노미, 인코포레이티드 | 귀 질환 및 병태를 치료하기 위한 귀 조제물 |
JP2012527406A (ja) | 2009-05-20 | 2012-11-08 | リングアル コンセグナ ピーティーワイ エルティーディー | 口腔内および/または舌下治療用製剤 |
TW201221505A (en) * | 2010-07-05 | 2012-06-01 | Sanofi Sa | Aryloxyalkylene-substituted hydroxyphenylhexynoic acids, process for preparation thereof and use thereof as a medicament |
AU2011343429B2 (en) | 2010-12-16 | 2016-10-20 | Sunovion Pharmaceuticals Inc. | Sublingual films |
JP6060268B2 (ja) * | 2012-10-25 | 2017-01-11 | ボルボ トラック コーポレイション | 車両用電子制御エアブレーキシステム、そのようなシステムを備える車両及びそのようなシステムを制御する方法 |
WO2014178892A1 (en) * | 2013-05-03 | 2014-11-06 | Scanlan Thomas S | Use of sobetirome in the treatment of x-linked adrenolenoleukodystrophy |
-
2013
- 2013-08-05 WO PCT/US2013/053640 patent/WO2014178892A1/en active Application Filing
- 2013-08-05 JP JP2016511718A patent/JP2016517883A/ja not_active Withdrawn
-
2014
- 2014-02-05 ES ES14791718T patent/ES2745532T3/es active Active
- 2014-02-05 AU AU2014260468A patent/AU2014260468A1/en not_active Abandoned
- 2014-02-05 CA CA2911309A patent/CA2911309A1/en not_active Abandoned
- 2014-02-05 JP JP2016511726A patent/JP6360552B6/ja active Active
- 2014-02-05 CN CN201480038129.XA patent/CN105431163A/zh active Pending
- 2014-02-05 RU RU2015151216A patent/RU2015151216A/ru not_active Application Discontinuation
- 2014-02-05 WO PCT/US2014/014943 patent/WO2014178931A1/en active Application Filing
- 2014-02-05 BR BR112015027682A patent/BR112015027682A2/pt not_active IP Right Cessation
- 2014-02-05 EP EP14791718.1A patent/EP2991670B8/en active Active
- 2014-02-05 SG SG11201509012QA patent/SG11201509012QA/en unknown
- 2014-02-05 MX MX2015015228A patent/MX2015015228A/es unknown
- 2014-02-05 SG SG10201709090UA patent/SG10201709090UA/en unknown
- 2014-02-05 US US14/888,577 patent/US10226438B2/en active Active
-
2015
- 2015-10-30 MX MX2021000538A patent/MX2021000538A/es unknown
-
2016
- 2016-09-09 HK HK16110708.4A patent/HK1222552A1/zh unknown
-
2018
- 2018-06-22 JP JP2018118891A patent/JP2018141024A/ja active Pending
- 2018-07-23 JP JP2018137754A patent/JP2018162321A/ja active Pending
-
2019
- 2019-02-13 US US16/275,117 patent/US20190175531A1/en not_active Abandoned
-
2020
- 2020-07-07 US US16/922,852 patent/US11510887B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
EP2991670A4 (en) | 2017-01-18 |
EP2991670B1 (en) | 2019-07-03 |
US20200405669A1 (en) | 2020-12-31 |
RU2015151216A (ru) | 2017-06-08 |
JP2018141024A (ja) | 2018-09-13 |
CA2911309A1 (en) | 2014-11-06 |
JP2018162321A (ja) | 2018-10-18 |
AU2014260468A1 (en) | 2015-11-19 |
WO2014178892A1 (en) | 2014-11-06 |
JP6360552B6 (ja) | 2018-08-15 |
JP2016517884A (ja) | 2016-06-20 |
CN105431163A (zh) | 2016-03-23 |
JP2016517883A (ja) | 2016-06-20 |
SG11201509012QA (en) | 2015-11-27 |
WO2014178931A1 (en) | 2014-11-06 |
HK1222552A1 (zh) | 2017-07-07 |
US10226438B2 (en) | 2019-03-12 |
US20160081955A1 (en) | 2016-03-24 |
US20190175531A1 (en) | 2019-06-13 |
SG10201709090UA (en) | 2017-12-28 |
US11510887B2 (en) | 2022-11-29 |
BR112015027682A2 (pt) | 2017-08-29 |
WO2014178931A8 (en) | 2015-11-26 |
EP2991670A1 (en) | 2016-03-09 |
ES2745532T3 (es) | 2020-03-02 |
MX2021000538A (es) | 2021-04-28 |
WO2014178892A8 (en) | 2015-12-17 |
JP6360552B2 (ja) | 2018-07-18 |
EP2991670B8 (en) | 2019-09-11 |
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