MX2015013696A - Sales de amina de pitavastatina y rosuvastatina. - Google Patents

Sales de amina de pitavastatina y rosuvastatina.

Info

Publication number
MX2015013696A
MX2015013696A MX2015013696A MX2015013696A MX2015013696A MX 2015013696 A MX2015013696 A MX 2015013696A MX 2015013696 A MX2015013696 A MX 2015013696A MX 2015013696 A MX2015013696 A MX 2015013696A MX 2015013696 A MX2015013696 A MX 2015013696A
Authority
MX
Mexico
Prior art keywords
amine salts
pitavastatin
rosuvastatin
hmg
coa reductase
Prior art date
Application number
MX2015013696A
Other languages
English (en)
Inventor
Ben De Lange
Erik De Vroom
Original Assignee
Dsm Sinochem Pharm Nl Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dsm Sinochem Pharm Nl Bv filed Critical Dsm Sinochem Pharm Nl Bv
Publication of MX2015013696A publication Critical patent/MX2015013696A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32—One oxygen, sulfur or nitrogen atom
    • C07D239/42—One nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/12—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D215/14—Radicals substituted by oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

La presente invención se relaciona con sales de amina que comprenden oxígeno de inhibidores de HMG-CoA reductasa, con un método para producir dichas sales de amina y con el uso de dichas sales de amina en la producción de sales farmacéuticamente aceptables de inhibidores de HGM-CoA reductasa.
MX2015013696A 2013-03-29 2014-03-28 Sales de amina de pitavastatina y rosuvastatina. MX2015013696A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP13161844 2013-03-29
EP13182234 2013-08-29
PCT/EP2014/056268 WO2014154857A1 (en) 2013-03-29 2014-03-28 Amine salts of pitavastatin and rosuvastatin

Publications (1)

Publication Number Publication Date
MX2015013696A true MX2015013696A (es) 2016-02-26

Family

ID=50391179

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2015013696A MX2015013696A (es) 2013-03-29 2014-03-28 Sales de amina de pitavastatina y rosuvastatina.

Country Status (6)

Country Link
US (1) US9676729B2 (es)
EP (1) EP2978744A1 (es)
CN (1) CN105377817A (es)
IL (1) IL241436B (es)
MX (1) MX2015013696A (es)
WO (1) WO2014154857A1 (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3087932A1 (en) * 2018-01-09 2019-07-18 Ligand Pharmaceuticals, Inc. Acetal compounds and therapeutic uses thereof

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3528186B2 (ja) 1991-06-24 2004-05-17 日産化学工業株式会社 光学活性キノリンメバロン酸のジアステレオマー塩
GB0218781D0 (en) * 2002-08-13 2002-09-18 Astrazeneca Ab Chemical process
WO2005077916A1 (en) * 2004-01-19 2005-08-25 Ranbaxy Laboratories Limited Salts of hmg-coa reductase inhibitors and use thereof
WO2006136407A1 (en) * 2005-06-24 2006-12-28 Lek Pharmaceuticals D.D. Process for preparing amorphous rosuvastatin calcium free of impurities
WO2010027060A1 (ja) 2008-09-05 2010-03-11 日産化学工業株式会社 ３，５－ジヒドロキシ－６－ヘプテン酸アミン塩類の製造方法
WO2012063115A2 (en) * 2010-11-11 2012-05-18 Jubilant Life Sciences Ltd. Process for the preparation of rosuvastatin calcium via novel amine intermediate
WO2012073256A1 (en) * 2010-11-29 2012-06-07 Cadila Healthcare Limited Salts of rosuvastatin
WO2012106584A2 (en) * 2011-02-04 2012-08-09 Dr. Reddy's Laboratories Ltd. Pitavastatin salts
US9630906B2 (en) 2013-03-29 2017-04-25 Dsm Sinochem Pharmaceuticals Netherlands B.V. Amine salts of pitavastatin and rosuvastatin

Also Published As

Publication number Publication date
EP2978744A1 (en) 2016-02-03
US9676729B2 (en) 2017-06-13
WO2014154857A1 (en) 2014-10-02
IL241436A0 (en) 2015-11-30
US20160075664A1 (en) 2016-03-17
IL241436B (en) 2018-11-29
CN105377817A (zh) 2016-03-02

Similar Documents

Publication Publication Date Title
TN2014000158A1 (en) Fused bicyclic oxazolidinone cetp inhibitor
PH12014502496A1 (en) Bicyclically substituted uracils and the use thereof
MX2020001756A (es) Compuestos deuterados del inhibidor vmat y el uso de dichos compuestos.
MX341456B (es) Amino-quinolinas como inhibidores de cinasa.
TN2013000400A1 (en) Imidazopyridazines as akt kinase inhibitors
MD20150071A2 (ro) Compuşi azabenzimidazolici ca inhibitori ai PDE4 izoenzimelor pentru tratamentul tulburărilor SNC şi altor afecţiuni
EP3027619A4 (en) Bicyclic ureas and thiadiazolidine-1,1-dioxides as cetp inhibitors
JO3318B1 (ar) مثبطات bace
WO2014153495A3 (en) Novel stat3 inhibitors
ZA201407329B (en) A system and a method for integrated production of first and second generation ethanol, and use of integration points for such production
MX2015013414A (es) N-(2-ciano heterociclil)pirazolo piridonas como inhibidores de janus quinasa.
IN2013MU01111A (es)
MX2016008406A (es) Preparacion farmaceutica combinada que comprende el bloqueante del receptor de la angiotensina ii y el inhibidor de la hmg-coa reductasa.
AU2013314244A8 (en) Novel inhibitor compounds of phosphodiesterase type 10A
WO2014155259A3 (en) Process for preparation of rivaroxaban
MX361000B (es) Sales de amina de pitavastatina y rosuvastatina.
MX2015007945A (es) Usos y métodos para el tratamiento de enfermedades o afecciones hepáticas.
MX2015013696A (es) Sales de amina de pitavastatina y rosuvastatina.
EP3015524A4 (en) AQUEOUS BASE COMPOSITION, PROCESS FOR OBTAINING THE SAME, AND USE OF THE COMPOSITION AS BIOADHESIVE
HK1221225A1 (zh) -二氨基吡唑激酶抑制劑的藥學上可接受的鹽
MX2015013551A (es) Sales de amina de pitavastatina farmaceuticamente aceptables.
IN2014DE01203A (es)
MX2017007510A (es) Un proceso para la fabricacion de idalopirdina.
MX2016002186A (es) Proceso para preparar dronedarona y sales de la misma.
EP2963020A4 (en) NOVEL CONNECTION, MANUFACTURING METHOD AND USE OF THE SAID CONNECTION