MX2015009260A - Regimen de glicosidasa selectiva para programacion inmunitaria y tratamiento del cancer. - Google Patents
Regimen de glicosidasa selectiva para programacion inmunitaria y tratamiento del cancer.Info
- Publication number
- MX2015009260A MX2015009260A MX2015009260A MX2015009260A MX2015009260A MX 2015009260 A MX2015009260 A MX 2015009260A MX 2015009260 A MX2015009260 A MX 2015009260A MX 2015009260 A MX2015009260 A MX 2015009260A MX 2015009260 A MX2015009260 A MX 2015009260A
- Authority
- MX
- Mexico
- Prior art keywords
- cancer
- treatment
- targets
- relates
- various
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/47—Hydrolases (3) acting on glycosyl compounds (3.2), e.g. cellulases, lactases
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
- C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
- C12Y302/01018—Exo-alpha-sialidase (3.2.1.18), i.e. trans-sialidase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
- C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
- C12Y302/01023—Beta-galactosidase (3.2.1.23), i.e. exo-(1-->4)-beta-D-galactanase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
- C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
- C12Y302/01049—Alpha-N-acetylgalactosaminidase (3.2.1.49)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
- C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
- C12Y302/0105—Alpha-N-acetylglucosaminidase (3.2.1.50)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
- C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
- C12Y302/01051—Alpha-L-fucosidase (3.2.1.51)
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Oncology (AREA)
- Hematology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
La presente invención se refiere al tratamiento y a la prevención del cáncer con glicosidasa. En diversos aspectos, la invención se refiere al tratamiento y al manejo del cáncer para prevenir la metástasis o la reaparición, o para mejorar el resultado y el índice de tratamientos exitosos con los regímenes terapéuticos convencionales. Un enorme nivel de investigación y desarrollo farmacéutico se centra en el tratamiento del cáncer. El cáncer sigue siendo uno de los objetivos principales de la industria farmacéutica. Los productos en desarrollo van desde inhibidores de cinasa hasta inhibidores de angiogénesis, anticuerpos monoclonales contra dianas tumorales, inhibidores de la apoptosis, vacunas antitumorales y agentes quimioterapéuticos convencionales contra diversas dianas tumorales y con diversos efectos citotóxicos.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201361754056P | 2013-01-18 | 2013-01-18 | |
PCT/US2014/011995 WO2014113641A1 (en) | 2013-01-18 | 2014-01-17 | Selective glycosidase regimen for immune programming and treatment of cancer |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2015009260A true MX2015009260A (es) | 2015-10-15 |
Family
ID=51210082
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2015009260A MX2015009260A (es) | 2013-01-18 | 2014-01-17 | Regimen de glicosidasa selectiva para programacion inmunitaria y tratamiento del cancer. |
Country Status (9)
Country | Link |
---|---|
US (2) | US20150352193A1 (es) |
EP (2) | EP2945644A4 (es) |
JP (1) | JP2016505043A (es) |
KR (1) | KR20150107738A (es) |
CN (1) | CN104936611A (es) |
AU (2) | AU2014207429B2 (es) |
CA (1) | CA2896899A1 (es) |
MX (1) | MX2015009260A (es) |
WO (1) | WO2014113641A1 (es) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR20150063079A (ko) | 2012-09-28 | 2015-06-08 | 엘리스 클라인 | 감염성 질환의 치료를 위한 글리코시다아제 요법 |
WO2016162867A1 (en) * | 2015-04-08 | 2016-10-13 | Efranat Ltd. | Combination therapy of macrophage activating factor and pd-1 signaling inhibitors |
CN105256036B (zh) * | 2015-10-26 | 2019-02-12 | 中国人民解放军第二军医大学 | 一种检测血清中lncARSR的试剂盒及其在检测肾癌舒尼替尼耐药中的应用 |
US11554145B2 (en) | 2019-01-31 | 2023-01-17 | The Chinese University Of Hong Kong | Therapeutic and prophylactic treatment for colorectal cancer |
CN111500715B (zh) * | 2019-01-31 | 2022-03-11 | 北京大学 | 用于预测结直肠癌术后复发与转移的检测组合物、检测装置、检测试剂盒及应用 |
Family Cites Families (28)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4071408A (en) | 1976-11-01 | 1978-01-31 | Research Corporation | Neuraminidase |
DE3302160A1 (de) | 1983-01-22 | 1984-07-26 | Ing. Erich Pfeiffer GmbH & Co KG, 7760 Radolfzell | Betaetigbare dosiereinrichtung |
DE3315334A1 (de) | 1983-04-28 | 1984-10-31 | Pfeiffer Erich Gmbh & Co Kg | Zerstaeuber- oder dosierpumpe |
DE3715301A1 (de) | 1987-05-08 | 1988-11-24 | Pfeiffer Erich Gmbh & Co Kg | Austragvorrichtung fuer medien |
DE3722470A1 (de) | 1987-07-08 | 1989-01-19 | Pfeiffer Erich Gmbh & Co Kg | Handbetaetigbare austragvorrichtung fuer medien |
US5326749A (en) | 1989-11-20 | 1994-07-05 | Nobuto Yamamoto | Macrophage activating factor from vitamin D binding protein |
IT1252228B (it) | 1991-12-17 | 1995-06-05 | T Associated Bio Technologies | Procedimento per la produzione di neuraminidasi |
US6562588B2 (en) | 1993-05-17 | 2003-05-13 | Genentech, Inc. | Sialidase and recombinant cell lines |
US5985859A (en) | 1994-04-14 | 1999-11-16 | The University Of Alabama | Methods of inhibiting bacterial sialidase |
US6410269B1 (en) * | 1995-06-07 | 2002-06-25 | Nobuto Yamamoto | Preparation of potent macrophage activating factors derived from cloned vitamin D binding protein and its domain and their therapeutic usage for cancer, HIV-infection and osteopetrosis |
DE19525734A1 (de) | 1995-07-14 | 1997-01-16 | Pfeiffer Erich Gmbh & Co Kg | Austragvorrichtung für fließfähige Medien, insbesondere für den Austrag in nur einem Hub |
DE60128793T2 (de) * | 2000-04-07 | 2008-02-07 | Signal Coordinating Therapy Inc. | Verfahren und Zusammensetzung zur Behandlung von Neoplasmen |
DE10146815B4 (de) | 2001-09-18 | 2005-05-04 | Ing. Erich Pfeiffer Gmbh | Spender für Medien |
US7201296B2 (en) | 2001-09-21 | 2007-04-10 | Ing. Erich Pfeiffer Gmbh | Dosing device with a pumping device |
DE10164452A1 (de) | 2001-12-21 | 2003-07-03 | Pfeiffer Erich Gmbh & Co Kg | Spender für Medien |
ES2616800T3 (es) | 2002-03-13 | 2017-06-14 | Genomic Health, Inc. | Obtención de perfil de expresión génica en tejidos tumorales biopsiados |
US20040231909A1 (en) | 2003-01-15 | 2004-11-25 | Tai-Yang Luh | Motorized vehicle having forward and backward differential structure |
JP4680898B2 (ja) | 2003-06-24 | 2011-05-11 | ジェノミック ヘルス, インコーポレイテッド | 癌再発の可能性の予測 |
CA2531967C (en) | 2003-07-10 | 2013-07-16 | Genomic Health, Inc. | Expression profile algorithm and test for cancer prognosis |
US7892752B2 (en) * | 2005-04-26 | 2011-02-22 | Dwek Raymond A | Glycosylation markers for cancer diagnosing and monitoring |
CA2667808A1 (en) * | 2006-11-02 | 2008-05-15 | Seattle Genetics, Inc. | Methods of treating neoplastic, autoimmune and inflammatory diseases |
ES2492469T3 (es) | 2007-02-20 | 2014-09-09 | Dsm Ip Assets B.V. | Nueva sialidasa |
JP5523313B2 (ja) * | 2007-07-03 | 2014-06-18 | チルドレンズ ホスピタル アンド リサーチ センター アット オークランド | ポリシアル酸誘導体、製造方法、ならびにがん抗原産生の増強およびターゲティングにおける使用 |
AU2009246009A1 (en) | 2008-05-14 | 2009-11-19 | University Health Network | Prognostic and predictive gene signature for non-small cell lung cancer and adjuvant chemotherapy |
WO2010051552A1 (en) | 2008-11-03 | 2010-05-06 | Precision Therapeutics, Inc. | Methods of simulating chemotherapy for a patient |
US20100331210A1 (en) | 2009-05-29 | 2010-12-30 | Precision Therapeutics, Inc. | Methods and systems for evaluating the sensitivity or resistance of tumor specimens to chemotherapeutic agents |
WO2011028485A2 (en) * | 2009-08-22 | 2011-03-10 | Charles Knezevich | Tumoricidal, bactericidal, or viricidal macrophage activation |
AU2012309586B2 (en) * | 2011-09-14 | 2016-01-28 | Saisei Mirai Clinic | Pharmaceutical composition and manufacturing method therefor |
-
2014
- 2014-01-17 EP EP14740546.8A patent/EP2945644A4/en not_active Withdrawn
- 2014-01-17 JP JP2015553844A patent/JP2016505043A/ja active Pending
- 2014-01-17 WO PCT/US2014/011995 patent/WO2014113641A1/en active Application Filing
- 2014-01-17 US US14/760,809 patent/US20150352193A1/en not_active Abandoned
- 2014-01-17 KR KR1020157018524A patent/KR20150107738A/ko not_active IP Right Cessation
- 2014-01-17 EP EP19162169.7A patent/EP3563864A1/en not_active Withdrawn
- 2014-01-17 AU AU2014207429A patent/AU2014207429B2/en not_active Ceased
- 2014-01-17 MX MX2015009260A patent/MX2015009260A/es unknown
- 2014-01-17 CA CA2896899A patent/CA2896899A1/en not_active Abandoned
- 2014-01-17 CN CN201480005012.1A patent/CN104936611A/zh active Pending
-
2019
- 2019-02-01 AU AU2019200688A patent/AU2019200688B2/en not_active Ceased
- 2019-03-14 US US16/353,168 patent/US20190201503A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
JP2016505043A (ja) | 2016-02-18 |
AU2019200688B2 (en) | 2020-08-06 |
CA2896899A1 (en) | 2014-07-24 |
AU2019200688A1 (en) | 2019-02-21 |
KR20150107738A (ko) | 2015-09-23 |
US20150352193A1 (en) | 2015-12-10 |
WO2014113641A1 (en) | 2014-07-24 |
EP2945644A1 (en) | 2015-11-25 |
US20190201503A1 (en) | 2019-07-04 |
CN104936611A (zh) | 2015-09-23 |
EP2945644A4 (en) | 2016-10-26 |
EP3563864A1 (en) | 2019-11-06 |
AU2014207429A1 (en) | 2015-07-02 |
AU2014207429B2 (en) | 2018-11-01 |
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