MX2015005862A - Enriquecimiento de plasmablastos especificos de antigeno. - Google Patents
Enriquecimiento de plasmablastos especificos de antigeno.Info
- Publication number
- MX2015005862A MX2015005862A MX2015005862A MX2015005862A MX2015005862A MX 2015005862 A MX2015005862 A MX 2015005862A MX 2015005862 A MX2015005862 A MX 2015005862A MX 2015005862 A MX2015005862 A MX 2015005862A MX 2015005862 A MX2015005862 A MX 2015005862A
- Authority
- MX
- Mexico
- Prior art keywords
- antigen
- enrichment
- specific plasmablasts
- plasmablasts
- specific
- Prior art date
Links
- 239000000427 antigen Substances 0.000 title abstract 3
- 102000036639 antigens Human genes 0.000 title abstract 3
- 108091007433 antigens Proteins 0.000 title abstract 3
- 210000003720 plasmablast Anatomy 0.000 title abstract 2
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
- C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
- C07K16/1018—Orthomyxoviridae, e.g. influenza virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/46—Cellular immunotherapy
- A61K39/461—Cellular immunotherapy characterised by the cell type used
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/46—Cellular immunotherapy
- A61K39/464—Cellular immunotherapy characterised by the antigen targeted or presented
- A61K39/4648—Bacterial antigens
- A61K39/46482—Clostridium, e.g. Clostridium tetani
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/46—Cellular immunotherapy
- A61K39/464—Cellular immunotherapy characterised by the antigen targeted or presented
- A61K39/464838—Viral antigens
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/06—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies from serum
- C07K16/065—Purification, fragmentation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/12—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
- C07K16/1267—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-positive bacteria
- C07K16/1282—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-positive bacteria from Clostridium (G)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0635—B lymphocytes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K39/46
- A61K2239/31—Indexing codes associated with cellular immunotherapy of group A61K39/46 characterized by the route of administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K39/46
- A61K2239/38—Indexing codes associated with cellular immunotherapy of group A61K39/46 characterised by the dose, timing or administration schedule
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Biomedical Technology (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Virology (AREA)
- Biotechnology (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Mycology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Hematology (AREA)
- General Engineering & Computer Science (AREA)
- Communicable Diseases (AREA)
- Pulmonology (AREA)
- Peptides Or Proteins (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Urology & Nephrology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Developmental Biology & Embryology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Food Science & Technology (AREA)
Abstract
La presente invención se refiere a métodos para el enriquecimiento de plasmablastos específicos de antígeno. Los métodos son útiles para la identificación de anticuerpos, incluyendo anticuerpos raros que reconocen más de un antígeno.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201261725764P | 2012-11-13 | 2012-11-13 | |
PCT/US2013/069588 WO2014078280A1 (en) | 2012-11-13 | 2013-11-12 | Enrichment of antigen-specific plasmablasts |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2015005862A true MX2015005862A (es) | 2015-09-10 |
Family
ID=49640215
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2015005862A MX2015005862A (es) | 2012-11-13 | 2013-11-12 | Enriquecimiento de plasmablastos especificos de antigeno. |
Country Status (16)
Country | Link |
---|---|
US (1) | US20140134638A1 (es) |
EP (1) | EP2920300B1 (es) |
JP (1) | JP2015536145A (es) |
KR (1) | KR20150084831A (es) |
CN (1) | CN104822828A (es) |
AR (1) | AR093447A1 (es) |
AU (1) | AU2013344992A1 (es) |
BR (1) | BR112015009933A2 (es) |
CA (1) | CA2889266A1 (es) |
HK (1) | HK1213009A1 (es) |
IL (1) | IL238302A0 (es) |
MX (1) | MX2015005862A (es) |
RU (1) | RU2015116927A (es) |
SG (1) | SG11201503706TA (es) |
WO (1) | WO2014078280A1 (es) |
ZA (1) | ZA201502711B (es) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20190031743A1 (en) | 2016-01-29 | 2019-01-31 | Achaogen, Inc. | Screening methods for identifying antibodies that bind cell surface epitopes |
JP2021521816A (ja) * | 2018-04-26 | 2021-08-30 | エフ・ホフマン−ラ・ロシュ・アクチェンゲゼルシャフト | 動物の集団内のある動物を追跡する方法およびシステム |
WO2023150760A2 (en) * | 2022-02-04 | 2023-08-10 | Cornell University | Enrichment and characterization of rare circulating cells, including progenitor cells, from peripheral blood, and uses thereof |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1993005796A1 (en) * | 1991-09-19 | 1993-04-01 | The Scripps Research Institute | Method for producing human antibodies in a non-human animal, and animals therefor |
US5663481A (en) * | 1993-08-06 | 1997-09-02 | Mount Sinai Hospital Corporation | Animal model of the human immune system |
US5811524A (en) * | 1995-06-07 | 1998-09-22 | Idec Pharmaceuticals Corporation | Neutralizing high affinity human monoclonal antibodies specific to RSV F-protein and methods for their manufacture and therapeutic use thereof |
IL118625A0 (en) * | 1996-06-11 | 1996-10-16 | Xtl Biopharmaceuticals Limited | Anti HBV antibodies |
CA2332336A1 (en) * | 1998-05-26 | 1999-12-02 | Erik Depla | Method for expanding primate b cells selectively in immunocompromised mice and producing large numbers of antigen-specific b lymphocytes for the production of primate monoclonal antibodies |
JP2008526205A (ja) * | 2004-12-31 | 2008-07-24 | ジェネンテック・インコーポレーテッド | Br3に結合するポリペプチド及びその使用 |
US20070269868A1 (en) * | 2006-05-19 | 2007-11-22 | Carvalho Jensen Anne E | Culture method for obtaining a clonal population of antigen-specific B cells |
US8133727B2 (en) * | 2008-11-21 | 2012-03-13 | California Institute Of Technology | In vitro human B lymphopoiesis culture system |
EP2454283B1 (en) * | 2009-07-15 | 2018-03-14 | AIMM Therapeutics B.V. | Means and methods for producing high affinity antibodies |
EP2703485B1 (en) * | 2011-03-30 | 2018-12-26 | National University Corporation University Of Toyama | Method for selecting plasma cells and plasmablasts, and method for producing target antigen-specific antibody |
GB201212550D0 (en) * | 2012-07-13 | 2012-08-29 | Novartis Ag | B cell assay |
-
2013
- 2013-11-12 AR ARP130104147A patent/AR093447A1/es unknown
- 2013-11-12 SG SG11201503706TA patent/SG11201503706TA/en unknown
- 2013-11-12 AU AU2013344992A patent/AU2013344992A1/en not_active Abandoned
- 2013-11-12 CA CA2889266A patent/CA2889266A1/en not_active Abandoned
- 2013-11-12 CN CN201380058934.4A patent/CN104822828A/zh active Pending
- 2013-11-12 KR KR1020157012137A patent/KR20150084831A/ko not_active Application Discontinuation
- 2013-11-12 RU RU2015116927A patent/RU2015116927A/ru not_active Application Discontinuation
- 2013-11-12 MX MX2015005862A patent/MX2015005862A/es unknown
- 2013-11-12 WO PCT/US2013/069588 patent/WO2014078280A1/en active Application Filing
- 2013-11-12 US US14/077,407 patent/US20140134638A1/en not_active Abandoned
- 2013-11-12 JP JP2015542000A patent/JP2015536145A/ja active Pending
- 2013-11-12 EP EP13795394.9A patent/EP2920300B1/en not_active Not-in-force
- 2013-11-12 BR BR112015009933A patent/BR112015009933A2/pt not_active IP Right Cessation
-
2015
- 2015-04-15 IL IL238302A patent/IL238302A0/en unknown
- 2015-04-21 ZA ZA2015/02711A patent/ZA201502711B/en unknown
-
2016
- 2016-01-26 HK HK16100861.8A patent/HK1213009A1/zh unknown
Also Published As
Publication number | Publication date |
---|---|
EP2920300A1 (en) | 2015-09-23 |
IL238302A0 (en) | 2015-06-30 |
AU2013344992A1 (en) | 2015-05-14 |
KR20150084831A (ko) | 2015-07-22 |
HK1213009A1 (zh) | 2016-06-24 |
CA2889266A1 (en) | 2014-05-22 |
WO2014078280A1 (en) | 2014-05-22 |
BR112015009933A2 (pt) | 2017-12-12 |
US20140134638A1 (en) | 2014-05-15 |
AR093447A1 (es) | 2015-06-10 |
SG11201503706TA (en) | 2015-06-29 |
EP2920300B1 (en) | 2018-09-12 |
RU2015116927A (ru) | 2017-01-10 |
CN104822828A (zh) | 2015-08-05 |
JP2015536145A (ja) | 2015-12-21 |
ZA201502711B (en) | 2016-11-30 |
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