MX2014012285A - Composicion farmaceutica que contiene un inhibidor de serina proteasa para tratar o prevenir infeccion por el virus de la influenza. - Google Patents
Composicion farmaceutica que contiene un inhibidor de serina proteasa para tratar o prevenir infeccion por el virus de la influenza.Info
- Publication number
- MX2014012285A MX2014012285A MX2014012285A MX2014012285A MX2014012285A MX 2014012285 A MX2014012285 A MX 2014012285A MX 2014012285 A MX2014012285 A MX 2014012285A MX 2014012285 A MX2014012285 A MX 2014012285A MX 2014012285 A MX2014012285 A MX 2014012285A
- Authority
- MX
- Mexico
- Prior art keywords
- methods
- treating
- inhibitor
- virus infection
- influenza virus
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/145—Orthomyxoviridae, e.g. influenza virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/42—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum viral
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Virology (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Pulmonology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Endocrinology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Peptides Or Proteins (AREA)
Abstract
La presente invención provee una composición para tratar o prevenir la infección por el virus de la influenza. La presente invención comprende la administración a un sujeto que así lo requiere de una composición farmacéutica que comprende un inhibidor de serina proteasa transmembrana (TTSP) tipo II. El inhibidor de TTSP funciona preferiblemente inhibiendo la escisión proteolítica de hemaglutinina (HA0) de la influenza en la subunidades funcionales HA1 y HA2. En ciertas modalidades, el inhibidor de TTSP es un inhibidor de proteasa serina S1 miembro 2 transmembrana (TMPRSS2), tal como un anticuerpo anti-TMPRSS2 o un fragmento de enlazamiento al antígeno del mismo.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261624519P | 2012-04-16 | 2012-04-16 | |
| US201361759469P | 2013-02-01 | 2013-02-01 | |
| PCT/US2013/036522 WO2013158516A1 (en) | 2012-04-16 | 2013-04-15 | Methods for treating or preventing influenza virus infection by administering a serine protease inhibitor |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2014012285A true MX2014012285A (es) | 2015-04-13 |
Family
ID=48184523
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2014012285A MX2014012285A (es) | 2012-04-16 | 2013-04-15 | Composicion farmaceutica que contiene un inhibidor de serina proteasa para tratar o prevenir infeccion por el virus de la influenza. |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US9498529B2 (es) |
| EP (2) | EP2838558A1 (es) |
| JP (2) | JP6446355B2 (es) |
| KR (1) | KR20150008383A (es) |
| CN (1) | CN104244978A (es) |
| AU (2) | AU2013249577A1 (es) |
| BR (1) | BR112014025339A8 (es) |
| CA (2) | CA3219083A1 (es) |
| HK (1) | HK1202817A1 (es) |
| MX (1) | MX2014012285A (es) |
| NZ (1) | NZ631105A (es) |
| SG (1) | SG11201405163RA (es) |
| WO (1) | WO2013158516A1 (es) |
| ZA (1) | ZA201406194B (es) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2749715C2 (ru) | 2016-02-29 | 2021-06-16 | Регенерон Фармасьютикалз, Инк. | Грызуны, характеризующиеся гуманизированным геном tmprss |
| KR101693243B1 (ko) * | 2016-06-15 | 2017-01-05 | 재단법인 한국파스퇴르연구소 | 인플루엔자 바이러스의 복제에 관여하는 신규 인간 유전자 및 이의 용도 |
| KR20200115576A (ko) * | 2018-01-26 | 2020-10-07 | 리제너론 파아마슈티컬스, 인크. | 항-tmprss2 항체 및 항원-결합 단편 |
| MX2022009476A (es) | 2020-02-10 | 2022-08-22 | Regeneron Pharma | Anticuerpos anti-tmprss2 y fragmentos de union a antigeno. |
| WO2021190980A1 (en) | 2020-03-22 | 2021-09-30 | Quadrucept Bio Limited | Multimers for viral strain evolution |
| WO2021195119A1 (en) * | 2020-03-24 | 2021-09-30 | Corcept Therapeutics Incorporated | Methods of reducing the risk of, severity of, and treating coronavirus infections |
| EP3964207A1 (en) | 2020-09-02 | 2022-03-09 | Christian-Albrechts-Universität zu Kiel | Antiviral pharmaceutical composition for topical administration |
| WO2022184659A1 (en) | 2021-03-01 | 2022-09-09 | Quadrucept Bio Limited | Antibody domains & multimers |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2000000605A1 (en) * | 1998-06-29 | 2000-01-06 | Myriad Genetics, Inc. | Tmprss2 is a tumor suppressor |
| WO2004097358A2 (en) | 2003-05-02 | 2004-11-11 | Bayer Healthcare Ag | Diagnostics and therapeutics for diseases associated with human transmembrane serine protease 2 (tmprss2) |
| ZA200705980B (en) * | 2005-01-07 | 2009-01-28 | Lexicon Pharmaceuticals Inc | Monoclonal antibodies against angiopoietin-like protein 4 (ANGPTL4) |
| US20070191322A1 (en) | 2006-02-01 | 2007-08-16 | Savage Paul B | Cationic Steroid Microbial Compositions and Methods of Use |
| JP2008247864A (ja) | 2007-03-30 | 2008-10-16 | Univ Of Tokushima | モザイクセリンプロテアーゼ、ｍｓｐとその用途 |
| JP2008308438A (ja) | 2007-06-14 | 2008-12-25 | Mitsubishi Tanabe Pharma Corp | 新規なインフルエンザ治療および／または予防薬 |
| BRPI1014745B1 (pt) | 2009-06-22 | 2020-10-20 | Borealis Ag | artigo para interior de automóveis com odor reduzido |
| CN104271605B (zh) * | 2012-02-15 | 2017-07-25 | 锡德克斯药物公司 | 环糊精衍生物的制造方法 |
-
2013
- 2013-04-15 MX MX2014012285A patent/MX2014012285A/es active IP Right Grant
- 2013-04-15 WO PCT/US2013/036522 patent/WO2013158516A1/en active Application Filing
- 2013-04-15 CA CA3219083A patent/CA3219083A1/en active Pending
- 2013-04-15 SG SG11201405163RA patent/SG11201405163RA/en unknown
- 2013-04-15 EP EP13718744.9A patent/EP2838558A1/en not_active Ceased
- 2013-04-15 CA CA2869010A patent/CA2869010A1/en not_active Withdrawn
- 2013-04-15 KR KR1020147028956A patent/KR20150008383A/ko not_active Application Discontinuation
- 2013-04-15 NZ NZ631105A patent/NZ631105A/en unknown
- 2013-04-15 EP EP19155349.4A patent/EP3536342A1/en not_active Withdrawn
- 2013-04-15 BR BR112014025339A patent/BR112014025339A8/pt not_active Application Discontinuation
- 2013-04-15 CN CN201380020133.9A patent/CN104244978A/zh active Pending
- 2013-04-15 US US13/862,497 patent/US9498529B2/en active Active
- 2013-04-15 AU AU2013249577A patent/AU2013249577A1/en not_active Abandoned
- 2013-04-15 JP JP2015507076A patent/JP6446355B2/ja active Active
-
2014
- 2014-08-22 ZA ZA2014/06194A patent/ZA201406194B/en unknown
-
2015
- 2015-04-10 HK HK15103529.7A patent/HK1202817A1/xx unknown
-
2017
- 2017-10-20 JP JP2017203146A patent/JP2018048169A/ja not_active Withdrawn
-
2018
- 2018-01-12 AU AU2018200265A patent/AU2018200265B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| SG11201405163RA (en) | 2014-09-26 |
| CN104244978A (zh) | 2014-12-24 |
| AU2013249577A1 (en) | 2014-10-02 |
| JP6446355B2 (ja) | 2018-12-26 |
| NZ631105A (en) | 2016-09-30 |
| WO2013158516A1 (en) | 2013-10-24 |
| HK1202817A1 (en) | 2015-10-09 |
| US9498529B2 (en) | 2016-11-22 |
| ZA201406194B (en) | 2016-08-31 |
| CA2869010A1 (en) | 2013-10-24 |
| EP2838558A1 (en) | 2015-02-25 |
| AU2018200265A1 (en) | 2018-02-01 |
| US20130273070A1 (en) | 2013-10-17 |
| KR20150008383A (ko) | 2015-01-22 |
| JP2018048169A (ja) | 2018-03-29 |
| EP3536342A1 (en) | 2019-09-11 |
| CA3219083A1 (en) | 2013-10-24 |
| BR112014025339A2 (pt) | 2013-10-24 |
| JP2015516975A (ja) | 2015-06-18 |
| BR112014025339A8 (pt) | 2018-01-16 |
| AU2018200265B2 (en) | 2019-07-18 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant or registration |