MX2013013185A - Proteina f, una nueva adhesina de haemophilus influenzae con propiedades de unión a la laminina y vitronectina. - Google Patents

Proteina f, una nueva adhesina de haemophilus influenzae con propiedades de unión a la laminina y vitronectina.

Info

Publication number
MX2013013185A
MX2013013185A MX2013013185A MX2013013185A MX2013013185A MX 2013013185 A MX2013013185 A MX 2013013185A MX 2013013185 A MX2013013185 A MX 2013013185A MX 2013013185 A MX2013013185 A MX 2013013185A MX 2013013185 A MX2013013185 A MX 2013013185A
Authority
MX
Mexico
Prior art keywords
protein
haemophilus influenzae
laminin
binding properties
vitronectin binding
Prior art date
Application number
MX2013013185A
Other languages
English (en)
Inventor
Kristian Riesbeck
Yu-Ching Su
Original Assignee
Riesbeck Healthcare Sweden Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Riesbeck Healthcare Sweden Ab filed Critical Riesbeck Healthcare Sweden Ab
Publication of MX2013013185A publication Critical patent/MX2013013185A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/145—Orthomyxoviridae, e.g. influenza virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/0208—Specific bacteria not otherwise provided for
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/09—Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
    • A61K39/092—Streptococcus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/102—Pasteurellales, e.g. Actinobacillus, Pasteurella; Haemophilus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/285—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Pasteurellaceae (F), e.g. Haemophilus influenza
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Oncology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Otolaryngology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Se describe una composición de vacuna que comprende una proteína, que puede detectarse en Haemophilus influenzae, que tiene una secuencia de aminoácidos como se describe en la SEQ ID NO: 1, o un fragmento de la misma; el fragmento comprende una secuencia de aminoácidos que tiene por lo menos 15 aminoácidos contiguos de la secuencia de aminoácidos de SEQ ID NO:1, y el fragmento (si es necesario, cuando se acopla a un portador), es capaz de provocar una respuesta inmune que reconoce el polilpéptido de la SEQ ID NO: 1.
MX2013013185A 2011-05-11 2012-05-11 Proteina f, una nueva adhesina de haemophilus influenzae con propiedades de unión a la laminina y vitronectina. MX2013013185A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161484697P 2011-05-11 2011-05-11
SE1150418 2011-05-11
PCT/SE2012/050503 WO2012154121A1 (en) 2011-05-11 2012-05-11 Protein f - a novel haemophilus influenzae adhesin with laminin and vitronectin binding properties

Publications (1)

Publication Number Publication Date
MX2013013185A true MX2013013185A (es) 2014-06-05

Family

ID=47139416

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2013013185A MX2013013185A (es) 2011-05-11 2012-05-11 Proteina f, una nueva adhesina de haemophilus influenzae con propiedades de unión a la laminina y vitronectina.

Country Status (13)

Country Link
US (1) US20140286977A1 (es)
EP (1) EP2707024A4 (es)
JP (1) JP2014516028A (es)
KR (1) KR20140066126A (es)
CN (1) CN103687613A (es)
AU (1) AU2012254213A1 (es)
BR (1) BR112013029024A2 (es)
CA (1) CA2835510A1 (es)
EA (1) EA201391669A1 (es)
IL (1) IL229343A0 (es)
MX (1) MX2013013185A (es)
SG (1) SG194886A1 (es)
WO (1) WO2012154121A1 (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20140066126A (ko) * 2011-05-11 2014-05-30 리스벡 헬스케어 스웨덴 에이비 단백질 f - 라미닌 및 비트로넥틴 결합 특성을 갖는 신규한 헤모필러스 인플루엔자 부착분자
CA2904388C (en) 2013-03-08 2023-09-26 Research Institute At Nationwide Children's Hospital Transcutaneous dosage formulation
TW201620927A (zh) * 2014-02-24 2016-06-16 葛蘭素史密斯克藍生物品公司 Ｕｓｐａ２蛋白質構築體及其用途

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT835663E (pt) * 1992-05-23 2010-01-04 Glaxosmithkline Biolog Sa Vacinas combinadas compreendendo o antigénio de superfície da hepatite b e outros antigénios
US6673910B1 (en) * 1999-04-08 2004-01-06 Genome Therapeutics Corporation Nucleic acid and amino acid sequences relating to M. catarrhalis for diagnostics and therapeutics
SE0102410D0 (sv) * 2001-07-04 2001-07-04 Arne Forsgren Novel surface exposed immunoglobulin D-binding protein from moraxella catarrhalis
MXPA04008890A (es) * 2002-03-15 2005-10-18 Wyeth Corp Mutantes de la proteina p4 de haemophilus influenzae no tipicable con actividad enzimatica reducida.
WO2006138527A2 (en) * 2005-06-16 2006-12-28 Children's Hospital, Inc. Genes of an otitis media isolate of nontypeable haemophilus influenzae
GB0410866D0 (en) * 2004-05-14 2004-06-16 Chiron Srl Haemophilius influenzae
CA2602665A1 (en) * 2005-03-30 2006-10-19 Novartis Vaccines And Diagnostics, Inc. Haemophilus influenzae type b
EP2548885B1 (en) * 2005-08-10 2017-10-18 Arne Forsgren AB Interaction of moraxella catarrhalis with epithelial cells, extracellular matrix proteins and the complement system
MY150105A (en) * 2006-01-17 2013-11-29 Forsgren Arne A novel surface exposed haemophilus influenzae protein (protein e; pe)
CN101081296B (zh) * 2006-05-29 2010-08-04 北京民海生物科技有限公司 一种b型流感嗜血杆菌荚膜多糖制备方法及其联合疫苗
KR20140066126A (ko) * 2011-05-11 2014-05-30 리스벡 헬스케어 스웨덴 에이비 단백질 f - 라미닌 및 비트로넥틴 결합 특성을 갖는 신규한 헤모필러스 인플루엔자 부착분자
WO2012170422A1 (en) * 2011-06-06 2012-12-13 Nationwide Children's Hospital, Inc. Proteomics based diagnostic detection method for chronic sinusitis
PE20150892A1 (es) * 2012-11-07 2015-06-11 Pfizer Anticuerpos anti-notch y conjugados de anticuerpo-farmaco

Also Published As

Publication number Publication date
CN103687613A (zh) 2014-03-26
SG194886A1 (en) 2013-12-30
JP2014516028A (ja) 2014-07-07
EA201391669A1 (ru) 2014-04-30
WO2012154121A1 (en) 2012-11-15
CA2835510A1 (en) 2012-11-15
EP2707024A1 (en) 2014-03-19
KR20140066126A (ko) 2014-05-30
US20140286977A1 (en) 2014-09-25
BR112013029024A2 (pt) 2017-10-31
EP2707024A4 (en) 2015-03-04
IL229343A0 (en) 2014-01-30
AU2012254213A1 (en) 2013-11-28

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