MX2012007397A - Composiciones y metodos para reducir la presion intraocular. - Google Patents
Composiciones y metodos para reducir la presion intraocular.Info
- Publication number
- MX2012007397A MX2012007397A MX2012007397A MX2012007397A MX2012007397A MX 2012007397 A MX2012007397 A MX 2012007397A MX 2012007397 A MX2012007397 A MX 2012007397A MX 2012007397 A MX2012007397 A MX 2012007397A MX 2012007397 A MX2012007397 A MX 2012007397A
- Authority
- MX
- Mexico
- Prior art keywords
- lowering intraocular
- pres sure
- triple combination
- iop
- intraocular pres
- Prior art date
Links
- 230000004410 intraocular pressure Effects 0.000 title abstract 5
- TWBNMYSKRDRHAT-RCWTXCDDSA-N (S)-timolol hemihydrate Chemical compound O.CC(C)(C)NC[C@H](O)COC1=NSN=C1N1CCOCC1.CC(C)(C)NC[C@H](O)COC1=NSN=C1N1CCOCC1 TWBNMYSKRDRHAT-RCWTXCDDSA-N 0.000 abstract 1
- XYLJNLCSTIOKRM-UHFFFAOYSA-N Alphagan Chemical compound C1=CC2=NC=CN=C2C(Br)=C1NC1=NCCN1 XYLJNLCSTIOKRM-UHFFFAOYSA-N 0.000 abstract 1
- AQOKCDNYWBIDND-FTOWTWDKSA-N bimatoprost Chemical compound CCNC(=O)CCC\C=C/C[C@H]1[C@@H](O)C[C@@H](O)[C@@H]1\C=C\[C@@H](O)CCC1=CC=CC=C1 AQOKCDNYWBIDND-FTOWTWDKSA-N 0.000 abstract 1
- 229960002470 bimatoprost Drugs 0.000 abstract 1
- 229960003679 brimonidine Drugs 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 229960004605 timolol Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/498—Pyrazines or piperazines ortho- and peri-condensed with carbocyclic ring systems, e.g. quinoxaline, phenazine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
- A61K31/5575—Eicosanoids, e.g. leukotrienes or prostaglandins having a cyclopentane, e.g. prostaglandin E2, prostaglandin F2-alpha
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Ophthalmology & Optometry (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
En la presente se describen composiciones para reducir la presión intraocular (IOP) de un ojo, que comprenden una combinación de agentes reductores de la IOP, bimatoprost, brimonidina y timolol. Además, se describen métodos para reducir la IOP en el ojo de un sujeto.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US28893609P | 2009-12-22 | 2009-12-22 | |
| US36174910P | 2010-07-06 | 2010-07-06 | |
| PCT/US2010/061563 WO2011087790A1 (en) | 2009-12-22 | 2010-12-21 | Triple combination for lowering intraocular pres sure |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2012007397A true MX2012007397A (es) | 2012-08-15 |
Family
ID=43743470
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2012007397A MX2012007397A (es) | 2009-12-22 | 2010-12-21 | Composiciones y metodos para reducir la presion intraocular. |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US20130116254A1 (es) |
| CN (1) | CN102695498A (es) |
| AR (1) | AR079696A1 (es) |
| BR (1) | BR112012017319A2 (es) |
| CL (1) | CL2012001736A1 (es) |
| CO (1) | CO6592061A2 (es) |
| CR (1) | CR20120360A (es) |
| EC (1) | ECSP12012033A (es) |
| GT (1) | GT201200213A (es) |
| IN (1) | IN2012DN06416A (es) |
| MX (1) | MX2012007397A (es) |
| NI (1) | NI201200112A (es) |
| PE (2) | PE20121468A1 (es) |
| TW (1) | TW201143773A (es) |
| WO (1) | WO2011087790A1 (es) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20050244458A1 (en) * | 2004-04-30 | 2005-11-03 | Allergan, Inc. | Sustained release intraocular implants and methods for treating ocular neuropathies |
| TR201818754T4 (tr) | 2010-07-29 | 2019-01-21 | Allergan Inc | Koruyucu içermeyen Brimonidin Ve Timolol Çözeltileri |
| US9248135B2 (en) | 2012-04-24 | 2016-02-02 | Allergan, Inc. | Prostaglandin and vasoconstrictor pharmaceutical compositions and methods of use |
| EP4420726A3 (en) * | 2015-03-19 | 2024-11-13 | Allergan, Inc. | Fixed dose combination of bromonidine and timolol |
| CN112566622A (zh) * | 2018-06-19 | 2021-03-26 | 细胞疗法有限责任公司 | 用于治疗青光眼或高眼压症的包含眼内压降低剂、cnp化合物、npr-b化合物、tie-2激动剂或神经营养剂的缓释药物递送系统 |
| US12064440B2 (en) * | 2022-03-21 | 2024-08-20 | Somerset Therapeutics, Llc | Ophthalmic gel compositions of bimatoprost and timolol and associated methods |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4994274A (en) | 1989-07-27 | 1991-02-19 | Allergan, Inc. | Intraocular pressure reducing 11,15-diacyl prostaglandins and method of using |
| US5028624A (en) | 1989-07-27 | 1991-07-02 | Allergan, Inc. | Intraocular pressure reducing 9,15-diacyl prostaglandins |
| US5034413A (en) | 1989-07-27 | 1991-07-23 | Allergan, Inc. | Intraocular pressure reducing 9,11-diacyl prostaglandins |
| US7030149B2 (en) * | 2002-04-19 | 2006-04-18 | Allergan, Inc. | Combination of brimonidine timolol for topical ophthalmic use |
| US7851504B2 (en) * | 2005-03-16 | 2010-12-14 | Allergan, Inc. | Enhanced bimatoprost ophthalmic solution |
-
2010
- 2010-12-21 PE PE2012000877A patent/PE20121468A1/es not_active Application Discontinuation
- 2010-12-21 US US13/698,182 patent/US20130116254A1/en not_active Abandoned
- 2010-12-21 BR BR112012017319A patent/BR112012017319A2/pt not_active Application Discontinuation
- 2010-12-21 PE PE2016000624A patent/PE20160904A1/es unknown
- 2010-12-21 CN CN2010800609772A patent/CN102695498A/zh active Pending
- 2010-12-21 MX MX2012007397A patent/MX2012007397A/es active IP Right Grant
- 2010-12-21 WO PCT/US2010/061563 patent/WO2011087790A1/en not_active Ceased
- 2010-12-22 AR ARP100104881A patent/AR079696A1/es not_active Application Discontinuation
- 2010-12-22 TW TW099145385A patent/TW201143773A/zh unknown
-
2012
- 2012-06-22 CL CL2012001736A patent/CL2012001736A1/es unknown
- 2012-06-22 NI NI201200112A patent/NI201200112A/es unknown
- 2012-06-22 GT GT201200213A patent/GT201200213A/es unknown
- 2012-06-29 CR CR20120360A patent/CR20120360A/es unknown
- 2012-07-11 EC ECSP12012033 patent/ECSP12012033A/es unknown
- 2012-07-19 CO CO12122166A patent/CO6592061A2/es not_active Application Discontinuation
- 2012-07-20 IN IN6416DEN2012 patent/IN2012DN06416A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CO6592061A2 (es) | 2013-01-02 |
| PE20121468A1 (es) | 2012-10-28 |
| CN102695498A (zh) | 2012-09-26 |
| BR112012017319A2 (pt) | 2016-04-19 |
| CR20120360A (es) | 2012-07-30 |
| AR079696A1 (es) | 2012-02-15 |
| GT201200213A (es) | 2014-08-29 |
| PE20160904A1 (es) | 2016-09-16 |
| NI201200112A (es) | 2013-04-09 |
| CL2012001736A1 (es) | 2012-10-12 |
| US20130116254A1 (en) | 2013-05-09 |
| WO2011087790A1 (en) | 2011-07-21 |
| ECSP12012033A (es) | 2012-10-30 |
| IN2012DN06416A (es) | 2015-10-09 |
| TW201143773A (en) | 2011-12-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| GD | Licence granted | ||
| FG | Grant or registration |