MX2011007940A - Conjugados de oligomero-fenotiazina. - Google Patents
Conjugados de oligomero-fenotiazina.Info
- Publication number
- MX2011007940A MX2011007940A MX2011007940A MX2011007940A MX2011007940A MX 2011007940 A MX2011007940 A MX 2011007940A MX 2011007940 A MX2011007940 A MX 2011007940A MX 2011007940 A MX2011007940 A MX 2011007940A MX 2011007940 A MX2011007940 A MX 2011007940A
- Authority
- MX
- Mexico
- Prior art keywords
- oligomer
- phenothiazine
- conjugates
- phenothiazine conjugates
- compounds
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
- A61K47/60—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/12—Antidiarrhoeals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Pain & Pain Management (AREA)
- Anesthesiology (AREA)
- Hospice & Palliative Care (AREA)
- Otolaryngology (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
Abstract
La invención se refiere a (entre otras cosas) conjugados de oligómero-fenotiazina y compuestos relacionados; cuando se administra un conjugado de la invención por cualquiera de una cantidad de vías de administración, presenta ventajas sobre los compuestos de fenotiazina no conjugados.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US14801609P | 2009-01-28 | 2009-01-28 | |
PCT/US2010/022342 WO2010088340A1 (en) | 2009-01-28 | 2010-01-28 | Oligomer-phenothiazine conjugates |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2011007940A true MX2011007940A (es) | 2011-08-15 |
Family
ID=42101449
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2011007940A MX2011007940A (es) | 2009-01-28 | 2010-01-28 | Conjugados de oligomero-fenotiazina. |
Country Status (8)
Country | Link |
---|---|
US (3) | US20120046279A1 (es) |
EP (1) | EP2391386B1 (es) |
JP (1) | JP5828587B2 (es) |
CN (1) | CN102300588B (es) |
AU (1) | AU2010208274B2 (es) |
CA (1) | CA2749126C (es) |
MX (1) | MX2011007940A (es) |
WO (1) | WO2010088340A1 (es) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP5643103B2 (ja) | 2007-11-28 | 2014-12-17 | ウェルズ ファーゴ バンク ナショナル アソシエイション | オリゴマー−三環物質コンジュゲート |
CN102300588B (zh) | 2009-01-28 | 2014-07-16 | 尼克塔治疗公司 | 低聚物-吩噻嗪缀合物 |
WO2011091050A1 (en) * | 2010-01-19 | 2011-07-28 | Nektar Therapeutics | Oligomer-tricyclic conjugates |
WO2013043744A2 (en) | 2011-09-21 | 2013-03-28 | Inception 1, Inc. | Tricyclic compounds useful as neurogenic and neuroprotective agents |
JP6265998B2 (ja) * | 2012-09-17 | 2018-01-24 | ネクター セラピューティクス | オリゴマー含有ベンズアミド系化合物 |
US9695138B1 (en) * | 2016-10-17 | 2017-07-04 | Acenda Pharma, Inc. | Phenothiazine derivatives and methods of use thereof |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2530451A (en) | 1950-11-21 | Phenothiazines | ||
US2607773A (en) | 1952-08-19 | Processes for preparing phenthi- | ||
US2519886A (en) | 1950-08-22 | Beta-bimethylaminoethylphenothia | ||
GB641452A (en) | 1946-12-09 | 1950-08-09 | Rhone Poulenc Sa | Improvements in or relating to the preparation of derivatives of phenthiazine |
US3987042A (en) | 1969-03-03 | 1976-10-19 | Claude Gueremy | Phenothiazine derivative |
FR2632521B1 (fr) | 1988-06-10 | 1990-09-14 | Rhone Poulenc Sante | Nouveaux derives de la phenothiazine, leur preparation et les compositions pharmaceutiques qui les contiennent |
US5672662A (en) | 1995-07-07 | 1997-09-30 | Shearwater Polymers, Inc. | Poly(ethylene glycol) and related polymers monosubstituted with propionic or butanoic acids and functional derivatives thereof for biotechnical applications |
WO2002057244A1 (en) | 2001-01-19 | 2002-07-25 | Cytokinetics, Inc. | Phenothiazine kinesin inhibitors |
US6835802B2 (en) | 2001-06-04 | 2004-12-28 | Nobex Corporation | Methods of synthesizing substantially monodispersed mixtures of polymers having polyethylene glycol moieties |
US7122201B2 (en) | 2001-06-28 | 2006-10-17 | Baxter International Inc. | Composition and method for reducing adverse interactions between phenothiazine derivatives and plasma using surfactants and amino acids |
WO2005020913A2 (en) * | 2003-08-25 | 2005-03-10 | Combinatorx, Incorporated | Formulations, conjugates, and combinations of drugs for the treatment of neoplasms |
EP2604282B1 (en) * | 2003-12-16 | 2019-06-19 | Nektar Therapeutics | Method for preparing of monodisperse oligo ethylene glycol |
US20080112257A1 (en) * | 2006-11-10 | 2008-05-15 | Masatoshi Masuda | Mixing device for tub |
AU2008226791B2 (en) * | 2007-03-12 | 2014-01-16 | Nektar Therapeutics | Oligomer-antihistamine conjugates |
CN102300588B (zh) | 2009-01-28 | 2014-07-16 | 尼克塔治疗公司 | 低聚物-吩噻嗪缀合物 |
-
2010
- 2010-01-28 CN CN201080005673.6A patent/CN102300588B/zh active Active
- 2010-01-28 EP EP10703204.7A patent/EP2391386B1/en active Active
- 2010-01-28 AU AU2010208274A patent/AU2010208274B2/en active Active
- 2010-01-28 CA CA2749126A patent/CA2749126C/en active Active
- 2010-01-28 MX MX2011007940A patent/MX2011007940A/es active IP Right Grant
- 2010-01-28 US US13/146,612 patent/US20120046279A1/en not_active Abandoned
- 2010-01-28 JP JP2011548281A patent/JP5828587B2/ja active Active
- 2010-01-28 WO PCT/US2010/022342 patent/WO2010088340A1/en active Application Filing
-
2018
- 2018-05-01 US US15/968,561 patent/US10485877B2/en active Active
-
2019
- 2019-10-11 US US16/599,605 patent/US10869933B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
US20200038517A1 (en) | 2020-02-06 |
US20180243429A1 (en) | 2018-08-30 |
US10485877B2 (en) | 2019-11-26 |
JP2012516347A (ja) | 2012-07-19 |
WO2010088340A1 (en) | 2010-08-05 |
EP2391386A1 (en) | 2011-12-07 |
EP2391386B1 (en) | 2018-06-27 |
CN102300588B (zh) | 2014-07-16 |
CA2749126C (en) | 2017-08-22 |
JP5828587B2 (ja) | 2015-12-09 |
AU2010208274B2 (en) | 2015-11-05 |
CA2749126A1 (en) | 2010-08-05 |
US10869933B2 (en) | 2020-12-22 |
AU2010208274A1 (en) | 2011-07-21 |
CN102300588A (zh) | 2011-12-28 |
US20120046279A1 (en) | 2012-02-23 |
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Legal Events
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