MX2010013683A - Bencimidazoles sustituidos para neurofibromatosis. - Google Patents

Bencimidazoles sustituidos para neurofibromatosis.

Info

Publication number
MX2010013683A
MX2010013683A MX2010013683A MX2010013683A MX2010013683A MX 2010013683 A MX2010013683 A MX 2010013683A MX 2010013683 A MX2010013683 A MX 2010013683A MX 2010013683 A MX2010013683 A MX 2010013683A MX 2010013683 A MX2010013683 A MX 2010013683A
Authority
MX
Mexico
Prior art keywords
carbon atoms
alkyl
formula
compound
neurofibromatosis
Prior art date
Application number
MX2010013683A
Other languages
English (en)
Spanish (es)
Inventor
Darrin Stuart
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of MX2010013683A publication Critical patent/MX2010013683A/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/41641,3-Diazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
MX2010013683A 2008-06-13 2009-06-11 Bencimidazoles sustituidos para neurofibromatosis. MX2010013683A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US6115608P 2008-06-13 2008-06-13
PCT/US2009/046971 WO2009152288A1 (en) 2008-06-13 2009-06-11 Substituted benzimidazoles for neurofibromatosis

Publications (1)

Publication Number Publication Date
MX2010013683A true MX2010013683A (es) 2011-04-26

Family

ID=40956523

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2010013683A MX2010013683A (es) 2008-06-13 2009-06-11 Bencimidazoles sustituidos para neurofibromatosis.

Country Status (12)

Country Link
US (1) US20110092546A1 (OSRAM)
EP (1) EP2288354A1 (OSRAM)
JP (1) JP2011524362A (OSRAM)
KR (1) KR20110025827A (OSRAM)
CN (1) CN102065859B (OSRAM)
AU (1) AU2009257487B2 (OSRAM)
BR (1) BRPI0915106A2 (OSRAM)
CA (1) CA2726376A1 (OSRAM)
MX (1) MX2010013683A (OSRAM)
RU (1) RU2011100106A (OSRAM)
TW (1) TW201004621A (OSRAM)
WO (1) WO2009152288A1 (OSRAM)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK2668210T3 (da) 2011-01-26 2020-08-24 Celldex Therapeutics Inc Anti-kit antistoffer og anvendelser deraf
RU2681730C2 (ru) 2012-07-25 2019-03-12 Селлдекс Терапьютикс Инк. Антитела против kit и их применения
CN113975386A (zh) * 2014-05-23 2022-01-28 塞尔德克斯医疗公司 嗜酸性粒细胞或肥大细胞相关病症的治疗
KR101880015B1 (ko) 2017-12-08 2018-07-19 아주대학교산학협력단 인터페론 감마를 유효성분으로 함유하는 신경섬유육종 예방 또는 치료용 조성물
CN113784713A (zh) 2019-01-11 2021-12-10 纳吉斯制药股份有限公司 白三烯合成抑制剂
CN117460509B (zh) * 2021-06-23 2025-03-28 正大天晴药业集团股份有限公司 作为c-Met激酶抑制剂的化合物治疗I型神经纤维瘤病的用途
JP2024534693A (ja) * 2021-10-08 2024-09-20 ウニベルシテ クロード ベルナール リヨン 1 組織球症若しくは頭蓋咽頭腫の治療又は予防における使用のためのベンズイミダゾール誘導体

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EA007987B1 (ru) * 2002-03-29 2007-02-27 Чирон Корпорейшн Замещённые бензазолы и их применение в качестве ингибиторов киназы raf
TW200804345A (en) * 2005-08-30 2008-01-16 Novartis Ag Substituted benzimidazoles and methods of preparation
GB0609378D0 (en) * 2006-05-11 2006-06-21 Novartis Ag Organic compounds
PE20130814A1 (es) * 2006-08-30 2013-08-08 Novartis Ag Sales de benzimidazolil piridil eteres y formulaciones que las contienen
WO2008070616A2 (en) * 2006-12-01 2008-06-12 University Of Utah Research Foundation METHODS AND COMPOSITIONS RELATED TO HIF-1α
EP2175885B1 (en) * 2007-07-30 2016-10-12 Ardea Biosciences, Inc. Combinations of mek inhibitors and raf kinase inhibitors and uses thereof
WO2009114703A2 (en) * 2008-03-12 2009-09-17 Fox Chase Cancer Center Combination therapy for the treatment of cancer

Also Published As

Publication number Publication date
BRPI0915106A2 (pt) 2016-02-10
KR20110025827A (ko) 2011-03-11
AU2009257487B2 (en) 2013-01-31
CN102065859B (zh) 2012-10-03
EP2288354A1 (en) 2011-03-02
TW201004621A (en) 2010-02-01
CN102065859A (zh) 2011-05-18
AU2009257487A1 (en) 2009-12-17
RU2011100106A (ru) 2012-10-27
WO2009152288A1 (en) 2009-12-17
CA2726376A1 (en) 2009-12-17
US20110092546A1 (en) 2011-04-21
JP2011524362A (ja) 2011-09-01

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Legal Events

Date Code Title Description
FA Abandonment or withdrawal