MX2010012836A - Formulaciones farmaceuticas y metodos de uso que combinan compuestos antiinflamatorios no esteroides con compuestos antihipertensivos. - Google Patents

Formulaciones farmaceuticas y metodos de uso que combinan compuestos antiinflamatorios no esteroides con compuestos antihipertensivos.

Info

Publication number
MX2010012836A
MX2010012836A MX2010012836A MX2010012836A MX2010012836A MX 2010012836 A MX2010012836 A MX 2010012836A MX 2010012836 A MX2010012836 A MX 2010012836A MX 2010012836 A MX2010012836 A MX 2010012836A MX 2010012836 A MX2010012836 A MX 2010012836A
Authority
MX
Mexico
Prior art keywords
compounds
inflammatory
methods
pharmaceutical formulations
steroidal anti
Prior art date
Application number
MX2010012836A
Other languages
English (en)
Inventor
Peter C Hoyle
Paul Waymack
Original Assignee
Kitov Pharmaceutical Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kitov Pharmaceutical Ltd filed Critical Kitov Pharmaceutical Ltd
Publication of MX2010012836A publication Critical patent/MX2010012836A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A61K31/405—Indole-alkanecarboxylic acids; Derivatives thereof, e.g. tryptophan, indomethacin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/63—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide
    • A61K31/635—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide having a heterocyclic ring, e.g. sulfadiazine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Cardiology (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)

Abstract

Una forma de dosificación oral de un fármaco antiinflamatorio no esteroideo (AINE) se hace más segura para uso prolongado o crónico para terapia antiinflamatoria, analgésica o antipirética mediante la combinación con un fármaco antihipertensivo. El fármaco antihipertensivo actúa profilácticamente para inhibir o reducir la hipertensión inducida por AINE y al hacerlo los efectos secundarios cardiovasculares adversos de los AINEs, tales como presión arterial alta, ataques al corazón, ataque de apoplejía, complicaciones oftalmológicas, y muerte, cuando los AINEs se usan repetidamente en un periodo prolongado de tiempo para reducir inflamación o en manejo del dolor.
MX2010012836A 2008-05-28 2009-05-22 Formulaciones farmaceuticas y metodos de uso que combinan compuestos antiinflamatorios no esteroides con compuestos antihipertensivos. MX2010012836A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US5678908P 2008-05-28 2008-05-28
US9797208P 2008-09-18 2008-09-18
PCT/US2009/044966 WO2009154944A2 (en) 2008-05-28 2009-05-22 Pharmaceutical formulations and methods of use which combine non-steroidal anti-inflammatory compounds with anti-hypertensive compounds

Publications (1)

Publication Number Publication Date
MX2010012836A true MX2010012836A (es) 2011-09-27

Family

ID=41434626

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2010012836A MX2010012836A (es) 2008-05-28 2009-05-22 Formulaciones farmaceuticas y metodos de uso que combinan compuestos antiinflamatorios no esteroides con compuestos antihipertensivos.

Country Status (7)

Country Link
US (2) US20110207724A1 (es)
EP (1) EP2285371A4 (es)
JP (1) JP2011525479A (es)
AU (1) AU2009260632A1 (es)
CA (1) CA2726337A1 (es)
MX (1) MX2010012836A (es)
WO (1) WO2009154944A2 (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3151822A4 (en) * 2014-06-08 2017-11-22 Autotelic LLC Fixed dose combination for pain relief without edema
WO2019067768A2 (en) * 2017-09-28 2019-04-04 Nevakar, Inc. FIXED DOSE COMBINATION FORMULATIONS FOR THE TREATMENT OF PAIN
US20210393553A1 (en) * 2018-11-01 2021-12-23 Imuneks Farma Ilac Sanayi Ve Ticaret A.S. Pharmaceutical combinations for the treatment of pain

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5155120A (en) * 1991-01-14 1992-10-13 Pfizer Inc Method for treating congestive heart failure
US20040186155A1 (en) * 2003-01-30 2004-09-23 Dayno Jeffrey Marc Combination therapy for the treatment or prevention of migraine
WO2006102476A2 (en) * 2005-03-21 2006-09-28 Vicus Therapeutics Spe 1, Llc Compositions and methods for ameliorating cachexia
US20070037797A1 (en) * 2005-08-15 2007-02-15 Hellstrom Harold R Method of reducing the risk of adverse cardiovascular (CV) events associated with the administration of pharmaceutical agents which favor CV events

Also Published As

Publication number Publication date
US20160243134A1 (en) 2016-08-25
US20110207724A1 (en) 2011-08-25
WO2009154944A3 (en) 2010-04-01
EP2285371A4 (en) 2012-01-25
WO2009154944A2 (en) 2009-12-23
AU2009260632A1 (en) 2009-12-23
EP2285371A2 (en) 2011-02-23
CA2726337A1 (en) 2009-12-23
JP2011525479A (ja) 2011-09-22

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