MX2010004998A - Catenados para inmunoestimulacion. - Google Patents
Catenados para inmunoestimulacion.Info
- Publication number
- MX2010004998A MX2010004998A MX2010004998A MX2010004998A MX2010004998A MX 2010004998 A MX2010004998 A MX 2010004998A MX 2010004998 A MX2010004998 A MX 2010004998A MX 2010004998 A MX2010004998 A MX 2010004998A MX 2010004998 A MX2010004998 A MX 2010004998A
- Authority
- MX
- Mexico
- Prior art keywords
- nucleic acid
- coding nucleic
- multimeric
- acid molecules
- molecules
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/117—Nucleic acids having immunomodulatory properties, e.g. containing CpG-motifs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/111—General methods applicable to biologically active non-coding nucleic acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/17—Immunomodulatory nucleic acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2320/00—Applications; Uses
- C12N2320/30—Special therapeutic applications
- C12N2320/31—Combination therapy
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Immunology (AREA)
- Biophysics (AREA)
- Public Health (AREA)
- Biochemistry (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Veterinary Medicine (AREA)
- Microbiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Oncology (AREA)
- Hematology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Saccharide Compounds (AREA)
Abstract
La invención se refiere a una molécula de ácido nucleico no codificante multimérica para modular la actividad del sistema inmune humano o animal, y a un procedimiento para su producción, y a una vacuna que contiene dicha molécula de ácido nucleico no codificante multimérica. Dichas moléculas de ácido nucleico no codificante multiméricas pueden ser moléculas de ácido nucleico no codificante constituidas por al menos dos de dichas moléculas (dímeros) o conjuntos de varias moléculas de ácido nucleico no codificante.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP07075967A EP2058397A1 (de) | 2007-11-07 | 2007-11-07 | Multimeres Assemblat zur Immunstimulation |
PCT/EP2008/009618 WO2009059805A1 (de) | 2007-11-07 | 2008-11-07 | Catenate zur immunstimulation |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2010004998A true MX2010004998A (es) | 2010-08-02 |
Family
ID=38990155
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2010004998A MX2010004998A (es) | 2007-11-07 | 2008-11-07 | Catenados para inmunoestimulacion. |
Country Status (13)
Country | Link |
---|---|
US (1) | US20100303803A1 (es) |
EP (2) | EP2058397A1 (es) |
JP (1) | JP2011502492A (es) |
KR (1) | KR20100087359A (es) |
CN (1) | CN101883854A (es) |
AU (1) | AU2008324384A1 (es) |
BR (1) | BRPI0820388A2 (es) |
CA (1) | CA2703983A1 (es) |
EA (1) | EA201000769A1 (es) |
IL (1) | IL205543A0 (es) |
MX (1) | MX2010004998A (es) |
TW (1) | TW200927148A (es) |
WO (1) | WO2009059805A1 (es) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2246433A1 (de) * | 2009-04-30 | 2010-11-03 | Mologen AG | Concatemere zur Immunmodulation |
US20130245102A1 (en) * | 2010-10-12 | 2013-09-19 | Research Foundation Of The City University Of New York | Novel dna templates for small rna production in mammalian cells |
EP3164113B1 (en) | 2014-06-04 | 2019-03-27 | Exicure, Inc. | Multivalent delivery of immune modulators by liposomal spherical nucleic acids for prophylactic or therapeutic applications |
LU92821B1 (en) | 2015-09-09 | 2017-03-20 | Mologen Ag | Combination comprising immunostimulatory oligonucleotides |
GB2542425A (en) | 2015-09-21 | 2017-03-22 | Mologen Ag | Means for the treatment of HIV |
US11364304B2 (en) | 2016-08-25 | 2022-06-21 | Northwestern University | Crosslinked micellar spherical nucleic acids |
WO2018209270A1 (en) | 2017-05-11 | 2018-11-15 | Northwestern University | Adoptive cell therapy using spherical nucleic acids (snas) |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE19935756A1 (de) * | 1999-07-27 | 2001-02-08 | Mologen Forschungs Entwicklung | Kovalent geschlossenes Nukleinsäuremolekül zur Immunstimulation |
EP1716234B1 (de) * | 2004-02-20 | 2013-10-02 | Mologen AG | Substituiertes, nicht-kodierendes nukleinsäuremolekül zur therapeutischen und prophylaktischen immunstimulation in menschen und höheren tieren |
WO2006015560A1 (de) * | 2004-08-09 | 2006-02-16 | Mologen Ag | Immunmodulierendes mittel in verbindung mit chemotherapeutischen massnahmen |
BRPI0711607A2 (pt) * | 2006-05-11 | 2012-11-06 | Mologen Ag | molécula multimérica para modulação da atividade do sistema imunológico humano ou animal, agente de combinação, kit, agente farmacêutico, molécula e uso da mesma |
-
2007
- 2007-11-07 EP EP07075967A patent/EP2058397A1/de not_active Withdrawn
-
2008
- 2008-11-07 EP EP08847608A patent/EP2207880A1/de not_active Withdrawn
- 2008-11-07 WO PCT/EP2008/009618 patent/WO2009059805A1/de active Application Filing
- 2008-11-07 EA EA201000769A patent/EA201000769A1/ru unknown
- 2008-11-07 TW TW097143438A patent/TW200927148A/zh unknown
- 2008-11-07 KR KR1020107012451A patent/KR20100087359A/ko not_active Application Discontinuation
- 2008-11-07 JP JP2010532512A patent/JP2011502492A/ja active Pending
- 2008-11-07 BR BRPI0820388-1A2A patent/BRPI0820388A2/pt not_active IP Right Cessation
- 2008-11-07 MX MX2010004998A patent/MX2010004998A/es not_active Application Discontinuation
- 2008-11-07 CA CA2703983A patent/CA2703983A1/en not_active Abandoned
- 2008-11-07 US US12/742,000 patent/US20100303803A1/en not_active Abandoned
- 2008-11-07 AU AU2008324384A patent/AU2008324384A1/en not_active Abandoned
- 2008-11-07 CN CN2008801185525A patent/CN101883854A/zh active Pending
-
2010
- 2010-05-04 IL IL205543A patent/IL205543A0/en unknown
Also Published As
Publication number | Publication date |
---|---|
KR20100087359A (ko) | 2010-08-04 |
TW200927148A (en) | 2009-07-01 |
EA201000769A1 (ru) | 2010-12-30 |
US20100303803A1 (en) | 2010-12-02 |
AU2008324384A1 (en) | 2009-05-14 |
WO2009059805A1 (de) | 2009-05-14 |
EP2058397A1 (de) | 2009-05-13 |
IL205543A0 (en) | 2010-12-30 |
BRPI0820388A2 (pt) | 2014-10-14 |
EP2207880A1 (de) | 2010-07-21 |
CN101883854A (zh) | 2010-11-10 |
JP2011502492A (ja) | 2011-01-27 |
CA2703983A1 (en) | 2009-05-14 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FA | Abandonment or withdrawal |