MX2010003550A - Forma de dosificacion intraoral con multiples porciones con propiedades organolepticas. - Google Patents
Forma de dosificacion intraoral con multiples porciones con propiedades organolepticas.Info
- Publication number
- MX2010003550A MX2010003550A MX2010003550A MX2010003550A MX2010003550A MX 2010003550 A MX2010003550 A MX 2010003550A MX 2010003550 A MX2010003550 A MX 2010003550A MX 2010003550 A MX2010003550 A MX 2010003550A MX 2010003550 A MX2010003550 A MX 2010003550A
- Authority
- MX
- Mexico
- Prior art keywords
- dosage form
- nicotine
- oral dosage
- organoleptic properties
- subject
- Prior art date
Links
- 239000006186 oral dosage form Substances 0.000 title abstract 2
- 239000002552 dosage form Substances 0.000 abstract 3
- SNICXCGAKADSCV-JTQLQIEISA-N (-)-Nicotine Chemical compound CN1CCC[C@H]1C1=CC=CN=C1 SNICXCGAKADSCV-JTQLQIEISA-N 0.000 abstract 2
- 239000013543 active substance Substances 0.000 abstract 2
- 229960002715 nicotine Drugs 0.000 abstract 2
- SNICXCGAKADSCV-UHFFFAOYSA-N nicotine Natural products CN1CCCC1C1=CC=CN=C1 SNICXCGAKADSCV-UHFFFAOYSA-N 0.000 abstract 2
- 230000035807 sensation Effects 0.000 abstract 2
- UIKROCXWUNQSPJ-VIFPVBQESA-N (-)-cotinine Chemical compound C1CC(=O)N(C)[C@@H]1C1=CC=CN=C1 UIKROCXWUNQSPJ-VIFPVBQESA-N 0.000 abstract 1
- UIKROCXWUNQSPJ-UHFFFAOYSA-N Cotinine Natural products C1CC(=O)N(C)C1C1=CC=CN=C1 UIKROCXWUNQSPJ-UHFFFAOYSA-N 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 229950006073 cotinine Drugs 0.000 abstract 1
- 239000002207 metabolite Substances 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 230000001737 promoting effect Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 230000001953 sensory effect Effects 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
- A23G1/00—Cocoa; Cocoa products, e.g. chocolate; Substitutes therefor
- A23G1/30—Cocoa products, e.g. chocolate; Substitutes therefor
- A23G1/32—Cocoa products, e.g. chocolate; Substitutes therefor characterised by the composition containing organic or inorganic compounds
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
- A23G3/00—Sweetmeats; Confectionery; Marzipan; Coated or filled products
- A23G3/34—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof
- A23G3/36—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
- A23G4/00—Chewing gum
- A23G4/06—Chewing gum characterised by the composition containing organic or inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
- A61K31/05—Phenols
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
- A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/4545—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/465—Nicotine; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/0216—Solid or semisolid forms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
- A61K9/0058—Chewing gums
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
- A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4808—Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/34—Tobacco-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Inorganic Chemistry (AREA)
- Birds (AREA)
- Physiology (AREA)
- Nutrition Science (AREA)
- Zoology (AREA)
- Addiction (AREA)
- Oral & Maxillofacial Surgery (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Psychiatry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
La presente invención se relaciona con una forma de dosificación intraoral con múltiples porciones, que comprende al menos un agente farmacéuticamente activo o un agente que promueve la salud, en donde al menos una porción comprende un componente para crear una sensación organoléptica perceptible; de cierto interés es el uso de marcadores/señales sensoriales como adyuvantes conceptuales para un sujeto que utiliza la forma de dosificación, por lo que la sensación organoléptica es tal que facilita que el sujeto identifique una porción y diferencie entre diferentes porciones de la misma, también están contempladas una forma de dosificación, un método y un sistema para suministrar agentes activos, tales como nicotina y/o metabolitos de la misma, tales como cotinina, N'-óxido de nicotina, nornicotina, (S)-nicotín-N-ß-glucurónido y mezclas, isómeros, sales y complejos de los mismos, así como el uso y producción de las formas de dosificación.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE0900397 | 2009-03-27 | ||
US12/430,238 US20100247586A1 (en) | 2009-03-27 | 2009-04-27 | Multi-Portion Intra-Oral Dosage Form With Organoleptic Properties |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2010003550A true MX2010003550A (es) | 2010-10-05 |
Family
ID=42791088
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2010003550A MX2010003550A (es) | 2009-03-27 | 2010-03-29 | Forma de dosificacion intraoral con multiples porciones con propiedades organolepticas. |
Country Status (11)
Country | Link |
---|---|
US (1) | US20100247586A1 (es) |
JP (1) | JP2010229131A (es) |
KR (1) | KR20100108307A (es) |
AR (1) | AR076153A1 (es) |
AU (1) | AU2010201229A1 (es) |
BR (1) | BRPI1001980A2 (es) |
CA (1) | CA2697867A1 (es) |
MX (1) | MX2010003550A (es) |
NZ (2) | NZ584267A (es) |
RU (1) | RU2490010C2 (es) |
ZA (1) | ZA201002188B (es) |
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AR045076A1 (es) * | 2003-07-24 | 2005-10-12 | Smithkline Beecham Plc | Composicion de pelicula que se disuelve oralmente, pelicula multicomponente que se disuelve oralmente, uso de la composicion de pelicula y de la pelicula que se disuelve oralmente para preparar un medicamento, forma de dosificacion oral y procedimiento para preparar la composicion de pelicula que se |
US20100124560A1 (en) * | 2008-11-14 | 2010-05-20 | Mcneil Ab | Multi portion intra-oral dosage form and use thereof |
EP2501234B1 (en) | 2009-11-20 | 2017-09-13 | Tonix Pharma Holdings Limited | Methods and compositions for treating symptoms associated with post-traumatic stress disorder using cyclobenzaprine |
US20110319389A1 (en) | 2010-06-24 | 2011-12-29 | Tonix Pharmaceuticals, Inc. | Methods and compositions for treating fatigue associated with disordered sleep using very low dose cyclobenzaprine |
US9155321B2 (en) * | 2010-08-11 | 2015-10-13 | R.J. Reynolds Tobacco Company | Meltable smokeless tobacco composition |
US11116237B2 (en) | 2010-08-11 | 2021-09-14 | R.J. Reynolds Tobacco Company | Meltable smokeless tobacco composition |
US9277976B2 (en) | 2011-01-24 | 2016-03-08 | Leonard G. Lorch | Dental floss |
US10206765B2 (en) | 2011-01-24 | 2019-02-19 | Leonard G. Lorch | Dental floss |
US9277977B2 (en) | 2011-01-24 | 2016-03-08 | Leonard G. Lorch | Dental floss |
US11998516B2 (en) | 2011-03-07 | 2024-06-04 | Tonix Pharma Holdings Limited | Methods and compositions for treating depression using cyclobenzaprine |
US9629392B2 (en) * | 2011-09-22 | 2017-04-25 | R.J. Reynolds Tobacco Company | Translucent smokeless tobacco product |
US9474303B2 (en) | 2011-09-22 | 2016-10-25 | R.J. Reynolds Tobacco Company | Translucent smokeless tobacco product |
US9084439B2 (en) | 2011-09-22 | 2015-07-21 | R.J. Reynolds Tobacco Company | Translucent smokeless tobacco product |
US20130078307A1 (en) * | 2011-09-22 | 2013-03-28 | Niconovum Usa, Inc. | Nicotine-containing pharmaceutical composition |
EP3108876A1 (en) * | 2011-10-13 | 2016-12-28 | Jaleva Pharmaceuticals LLC | Methods and compositions for rapid transbuccal delivery of active agents |
US9907748B2 (en) * | 2011-10-21 | 2018-03-06 | Niconovum Usa, Inc. | Excipients for nicotine-containing therapeutic compositions |
US20130177646A1 (en) * | 2012-01-05 | 2013-07-11 | Mcneil Ab | Solid Nicotine-Comprising Dosage Form with Reduced Organoleptic Disturbance |
US9763928B2 (en) * | 2012-02-10 | 2017-09-19 | Niconovum Usa, Inc. | Multi-layer nicotine-containing pharmaceutical composition |
PT2861223T (pt) * | 2012-06-15 | 2022-11-07 | Tonix Pharmaceuticals Inc | Composições e métodos de absorção transmucosa |
WO2014027980A1 (en) * | 2012-08-17 | 2014-02-20 | Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi | Oral film formulations comprising dapoxetine and tadalafil |
US10130120B2 (en) | 2013-03-15 | 2018-11-20 | Altria Client Services Llc | Use of pectin or other anionic polymers in the stabilization and controlled release of nicotine in oral sensorial tobacco products or nicotine containing non-tobacco oral sensorial products |
EP2968992B8 (en) | 2013-03-15 | 2020-01-15 | Tonix Pharma Holdings Limited | Eutectic formulations of cyclobenzaprine hydrochloride and mannitol |
CN103284319A (zh) * | 2013-06-20 | 2013-09-11 | 昌宁德康生物科技有限公司 | 一种金雀花碱替代尼古丁口腔雾化液及其制备方法 |
CN107072968B (zh) | 2014-09-18 | 2021-01-12 | 通尼克斯制药控股有限公司 | 环苯扎林盐酸盐的低共熔混合物配制剂 |
KR101695071B1 (ko) * | 2014-12-26 | 2017-01-11 | 연세대학교 산학협력단 | 액상으로 약물을 분산시킨 필름형태의 약제학적 조성물 |
ES2972665T3 (es) * | 2015-03-26 | 2024-06-13 | Patheon Softgels Inc | Cápsulas liquisoft |
FR3034991A1 (fr) * | 2015-04-17 | 2016-10-21 | Bertin Pharma | Comprime pharmaceutique bicouche, procede de fabrication et utilisation comme medicament |
US10016471B2 (en) | 2015-06-29 | 2018-07-10 | Phloronol, Inc. | Solid pharmaceutical compositions of brown algae |
JP2019501207A (ja) * | 2016-01-08 | 2019-01-17 | シーティーシー バイオ,インコーポレイテッド | バレニクリンまたはこの薬学的に許容可能な塩を含有する、味の遮蔽された口腔投与用薬学製剤 |
ES2814296T3 (es) | 2016-04-21 | 2021-03-26 | Fertin Pharma As | Producto para administración de nicotina, usos relacionados y formas de dosificación oral y métodos de producción |
WO2017189375A1 (en) * | 2016-04-27 | 2017-11-02 | Axim Biotechnologies, Inc. | Chewing gum composition comprising cannabinoids and nicotine |
US10653639B2 (en) | 2016-05-16 | 2020-05-19 | Cv Sciences, Inc. | Pharmaceutical formulations containing cannabidiol and nicotine for treating smokeless tobacco addiction |
EP3525792A4 (en) * | 2016-10-11 | 2020-04-22 | Aucta Pharmaceuticals | POWDER FOR ORAL SUSPENSION CONTAINING LAMOTRIGIN |
JP7137850B2 (ja) * | 2017-03-03 | 2022-09-15 | シーティーシー バイオ インク | バレニクリンまたはその薬学的に許容可能な塩の包接複合体を含む口腔投与用製剤 |
EP3723860A1 (en) | 2017-12-11 | 2020-10-21 | Tonix Pharma Holdings Limited | Cyclobenzaprine treatment for agitation, psychosis and cognitive decline in dementia and neurodegenerative conditions |
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US20230053622A1 (en) * | 2020-01-15 | 2023-02-23 | Mcneil Ab | Lozenge |
US20220175662A1 (en) * | 2020-11-14 | 2022-06-09 | Regents Of The University Of Minnesota | Sustained release device for treatment of parkinson's disease and other disorders |
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-
2009
- 2009-04-27 US US12/430,238 patent/US20100247586A1/en not_active Abandoned
-
2010
- 2010-03-26 JP JP2010071926A patent/JP2010229131A/ja active Pending
- 2010-03-26 AU AU2010201229A patent/AU2010201229A1/en not_active Abandoned
- 2010-03-26 RU RU2010111715/15A patent/RU2490010C2/ru not_active IP Right Cessation
- 2010-03-26 AR ARP100100980A patent/AR076153A1/es not_active Application Discontinuation
- 2010-03-26 ZA ZA2010/02188A patent/ZA201002188B/en unknown
- 2010-03-26 CA CA2697867A patent/CA2697867A1/en not_active Abandoned
- 2010-03-26 NZ NZ584267A patent/NZ584267A/en not_active IP Right Cessation
- 2010-03-26 NZ NZ598993A patent/NZ598993A/en not_active IP Right Cessation
- 2010-03-26 BR BRPI1001980-4A patent/BRPI1001980A2/pt not_active IP Right Cessation
- 2010-03-29 MX MX2010003550A patent/MX2010003550A/es not_active Application Discontinuation
- 2010-03-29 KR KR1020100028173A patent/KR20100108307A/ko unknown
Also Published As
Publication number | Publication date |
---|---|
RU2010111715A (ru) | 2011-10-10 |
US20100247586A1 (en) | 2010-09-30 |
ZA201002188B (en) | 2011-12-28 |
JP2010229131A (ja) | 2010-10-14 |
CA2697867A1 (en) | 2010-09-27 |
AR076153A1 (es) | 2011-05-18 |
NZ584267A (en) | 2012-04-27 |
NZ598993A (en) | 2014-02-28 |
RU2490010C2 (ru) | 2013-08-20 |
AU2010201229A1 (en) | 2010-11-11 |
BRPI1001980A2 (pt) | 2011-07-26 |
KR20100108307A (ko) | 2010-10-06 |
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FA | Abandonment or withdrawal |