MX2009011852A - Composiciones que comprenden compuestos macrolidos de alcoxieter de c-13 y compuestos de fenilpirazol. - Google Patents

Composiciones que comprenden compuestos macrolidos de alcoxieter de c-13 y compuestos de fenilpirazol.

Info

Publication number
MX2009011852A
MX2009011852A MX2009011852A MX2009011852A MX2009011852A MX 2009011852 A MX2009011852 A MX 2009011852A MX 2009011852 A MX2009011852 A MX 2009011852A MX 2009011852 A MX2009011852 A MX 2009011852A MX 2009011852 A MX2009011852 A MX 2009011852A
Authority
MX
Mexico
Prior art keywords
compounds
compositions
alkoxyether
phenylpyrazole
macrolide
Prior art date
Application number
MX2009011852A
Other languages
English (en)
Inventor
Albert Boeckh
Mark D Soll
Natalya Shub
Original Assignee
Merial Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merial Ltd filed Critical Merial Ltd
Publication of MX2009011852A publication Critical patent/MX2009011852A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/12—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains three hetero rings
    • C07D493/20—Spiro-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Abstract

Se proporciona un derivado de ivermectina novedoso y composiciones para el tratamiento o profilaxis de infestaciones parasíticas en mamíferos o aves que comprenden: (A) una cantidad farmacéuticamente efectiva de un compuesto de 1-N-fenilpirazol; (B) una cantidad farmacéuticamente efectiva de un derivado de ivermectina de la fórmula (II) en donde: R14 representa -(CH2)s-O-Z en donde, s es 1 o 2; Y representa -CH(OR15)-, -C(=O)- o -C(=NOR15); R15 representa hidrógeno, alquilo o fenilo; y R16 representa -CH3 o -CH2CH3 Z es alquilo, alquenilo, alquinilo, acilo, alquilalcoxi, arilo, alcanoiloxi, alcoxicarbonilo, alquenoilo, alquinoilo o aroilo.
MX2009011852A 2007-05-03 2007-05-03 Composiciones que comprenden compuestos macrolidos de alcoxieter de c-13 y compuestos de fenilpirazol. MX2009011852A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US2007/010611 WO2008136791A1 (en) 2007-05-03 2007-05-03 Compositions comprising c-13 alkoxyether macrolide compounds and phenylpyrazole compounds

Publications (1)

Publication Number Publication Date
MX2009011852A true MX2009011852A (es) 2009-12-11

Family

ID=38895805

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2009011852A MX2009011852A (es) 2007-05-03 2007-05-03 Composiciones que comprenden compuestos macrolidos de alcoxieter de c-13 y compuestos de fenilpirazol.

Country Status (9)

Country Link
EP (1) EP2155755B1 (es)
JP (1) JP2010526065A (es)
CN (1) CN101679451A (es)
AU (1) AU2007352619B2 (es)
BR (1) BRPI0721629B1 (es)
CA (1) CA2684926C (es)
ES (1) ES2595499T3 (es)
MX (1) MX2009011852A (es)
WO (1) WO2008136791A1 (es)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0905365D0 (en) * 2009-03-27 2009-05-13 Norbrook Lab Ltd A topical parasiticide composition
EP2512467A1 (en) 2009-12-17 2012-10-24 Merial Limited Compositions comprising macrocyclic lactone compounds and spirodioxepinoindoles
UA108641C2 (uk) 2010-04-02 2015-05-25 Паразитицидна композиція, яка містить чотири активних агенти, та спосіб її застосування
ES2777928T3 (es) 2011-10-18 2020-08-06 Institut National De Rech Pour L'agriculture L'alimentation Et L'environnement Uso de derivado de avermectina para aumentar la biodisponibilidad y eficacia de lactonas macrocíclicas
LT2811998T (lt) 2012-02-06 2019-02-25 Merial, Inc. Paraziticidinės peroralinės veterinarinės kompozicijos, apimančios sistemiškai veikiančius aktyviuosius agentus, būdai ir jų panaudojimas
EP2833866B1 (en) 2012-04-04 2018-11-21 Intervet International B.V. Soft chewable pharmaceutical products
ES2748631T3 (es) * 2012-09-07 2020-03-17 Zoetis Services Llc Combinaciones parasiticidas de isoxazolina espirocíclica
WO2019157241A1 (en) * 2018-02-08 2019-08-15 Boehringer Ingelheim Animal Health USA Inc. Parasiticidal compositions comprising eprinomectin and praziquantel, methods and uses thereof
CN110938081B (zh) * 2019-12-11 2021-03-26 台州职业技术学院 一种大环内酯类新化合物、药物组合物及其制备方法与应用
CN113461757B (zh) * 2021-06-25 2023-08-22 湖州师范学院 新型十六元大环内酯的制备方法及用途

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUT39739A (en) * 1984-12-04 1986-10-29 Ciba Geigy Ag Process for production of derivatives of 13,3-milbemycin and medical preparatives containing thereof
US4587247A (en) * 1985-02-25 1986-05-06 Merck & Co., Inc. Substituted and unsubstituted 13-(alkoxy)methoxy derivatives of the avermectin aglycones, compositions and use
EP0530901A1 (en) * 1991-09-04 1993-03-10 Merck & Co. Inc. 13-beta-O-methoxymethyl-22,23-dihydro avermectin B1A/B1B aglycone
US6426333B1 (en) * 1996-09-19 2002-07-30 Merial Spot-on formulations for combating parasites
FR2753377B1 (fr) * 1996-09-19 1999-09-24 Rhone Merieux Nouvelle association parasiticide a base de 1-n-phenylpyra- zoles et de lactones macrocycliques endectocides

Also Published As

Publication number Publication date
CA2684926C (en) 2014-09-30
JP2010526065A (ja) 2010-07-29
ES2595499T3 (es) 2016-12-30
EP2155755A1 (en) 2010-02-24
AU2007352619B2 (en) 2013-07-18
CA2684926A1 (en) 2008-11-13
CN101679451A (zh) 2010-03-24
WO2008136791A1 (en) 2008-11-13
BRPI0721629B1 (pt) 2019-03-19
BRPI0721629A2 (pt) 2013-01-22
EP2155755B1 (en) 2016-07-06
AU2007352619A1 (en) 2008-11-13

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