MX2009005125A - Pirrolo[1,2-a]imidazoldiona efectiva en el tratamiento de neurotoxicidad periferica inducida por agentes quimioterapeuticos. - Google Patents

Pirrolo[1,2-a]imidazoldiona efectiva en el tratamiento de neurotoxicidad periferica inducida por agentes quimioterapeuticos.

Info

Publication number
MX2009005125A
MX2009005125A MX2009005125A MX2009005125A MX2009005125A MX 2009005125 A MX2009005125 A MX 2009005125A MX 2009005125 A MX2009005125 A MX 2009005125A MX 2009005125 A MX2009005125 A MX 2009005125A MX 2009005125 A MX2009005125 A MX 2009005125A
Authority
MX
Mexico
Prior art keywords
treatment
imidazoledione
pyrrolo
effective
chemotherapeutic agents
Prior art date
Application number
MX2009005125A
Other languages
English (en)
Inventor
Carlo Farina
Carla Ghelardini
Paola Petrillo
Original Assignee
Neurotune Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=37882430&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX2009005125(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Neurotune Ag filed Critical Neurotune Ag
Publication of MX2009005125A publication Critical patent/MX2009005125A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4188—1,3-Diazoles condensed with other heterocyclic ring systems, e.g. biotin, sorbinil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Epidemiology (AREA)
  • Toxicology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Se divulga la utilización de un compuesto de la formula (I) para el tratamiento y/o prevención de neurotoxicidad periférica inducida por quimioterapia CCIPN). La invención incluye composiciones farmacéuticas en que está presente el compuesto de la fórmula (I) en una mezcla de compuestos anticancerígenos. Se proporciona también un tratamiento anticancerígeno mejorado con la reducción de efectos secundarios relacionados con CIPN.
MX2009005125A 2006-11-15 2007-11-14 Pirrolo[1,2-a]imidazoldiona efectiva en el tratamiento de neurotoxicidad periferica inducida por agentes quimioterapeuticos. MX2009005125A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP06124142A EP1925304A1 (en) 2006-11-15 2006-11-15 Pyrrolo[1,2-a]imidazoledione effective in the treatment of peripheral neurotoxicity induced by chemotherapeutic agents
PCT/EP2007/062323 WO2008058988A1 (en) 2006-11-15 2007-11-14 Pyrrolo[1,2-a]imidazoledione effective in the treatment of peripheral neurotoxicity induced by chemotherapeutic agents

Publications (1)

Publication Number Publication Date
MX2009005125A true MX2009005125A (es) 2009-11-02

Family

ID=37882430

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2009005125A MX2009005125A (es) 2006-11-15 2007-11-14 Pirrolo[1,2-a]imidazoldiona efectiva en el tratamiento de neurotoxicidad periferica inducida por agentes quimioterapeuticos.

Country Status (19)

Country Link
US (1) US7973066B2 (es)
EP (2) EP1925304A1 (es)
JP (1) JP2010509389A (es)
CN (1) CN101605541A (es)
AR (1) AR063819A1 (es)
AT (1) ATE478668T1 (es)
AU (1) AU2007321218A1 (es)
BR (1) BRPI0718904A2 (es)
CA (1) CA2669853A1 (es)
CL (1) CL2007003281A1 (es)
DE (1) DE602007008759D1 (es)
EA (1) EA200900552A1 (es)
ES (1) ES2347380T3 (es)
IL (1) IL198689A0 (es)
MX (1) MX2009005125A (es)
NZ (1) NZ576995A (es)
PE (1) PE20081494A1 (es)
WO (1) WO2008058988A1 (es)
ZA (1) ZA200904148B (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ITMI20030573A1 (it) * 2003-03-24 2004-09-25 Nikem Research Srl Composti ad azione nootropica, loro preparazione,
US9125898B2 (en) 2008-11-14 2015-09-08 Neurotune Ag Acetam derivatives for pain relief
CN106660950A (zh) * 2014-07-31 2017-05-10 葛兰素史密斯克莱知识产权发展有限公司 Cxcr2拮抗剂用于预防和/或治疗化疗诱导的周围神经病变(cipn)的用途
US20220313649A1 (en) * 2019-09-02 2022-10-06 Syddansk Universitet P-gp inducers as protectors against chemotherapy-induced side effects, such as peripheral neuropathy (cipn) and hair loss

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ITMI20030573A1 (it) * 2003-03-24 2004-09-25 Nikem Research Srl Composti ad azione nootropica, loro preparazione,

Also Published As

Publication number Publication date
US7973066B2 (en) 2011-07-05
CN101605541A (zh) 2009-12-16
ATE478668T1 (de) 2010-09-15
NZ576995A (en) 2010-12-24
ES2347380T3 (es) 2010-10-28
WO2008058988A1 (en) 2008-05-22
US20100062077A1 (en) 2010-03-11
AU2007321218A1 (en) 2008-05-22
PE20081494A1 (es) 2008-12-19
CA2669853A1 (en) 2008-05-22
JP2010509389A (ja) 2010-03-25
EP1925304A1 (en) 2008-05-28
IL198689A0 (en) 2010-02-17
DE602007008759D1 (de) 2010-10-07
EP2094265A1 (en) 2009-09-02
CL2007003281A1 (es) 2008-06-27
EP2094265B1 (en) 2010-08-25
AR063819A1 (es) 2009-02-18
BRPI0718904A2 (pt) 2013-12-10
ZA200904148B (en) 2010-04-28
EA200900552A1 (ru) 2009-10-30

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