MX2008015969A - Productos terapeuticos y de diagnostico y metodos novedosos. - Google Patents
Productos terapeuticos y de diagnostico y metodos novedosos.Info
- Publication number
- MX2008015969A MX2008015969A MX2008015969A MX2008015969A MX2008015969A MX 2008015969 A MX2008015969 A MX 2008015969A MX 2008015969 A MX2008015969 A MX 2008015969A MX 2008015969 A MX2008015969 A MX 2008015969A MX 2008015969 A MX2008015969 A MX 2008015969A
- Authority
- MX
- Mexico
- Prior art keywords
- methods
- novel therapeutic
- diagnostic products
- diagnosis
- development
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 2
- 239000012502 diagnostic product Substances 0.000 title 1
- 230000001225 therapeutic effect Effects 0.000 title 1
- 108091032151 5-hydroxytryptamine receptor family Proteins 0.000 abstract 2
- 102000014630 G protein-coupled serotonin receptor activity proteins Human genes 0.000 abstract 2
- 241001465754 Metazoa Species 0.000 abstract 2
- 238000011161 development Methods 0.000 abstract 2
- 238000003745 diagnosis Methods 0.000 abstract 2
- 238000011282 treatment Methods 0.000 abstract 2
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 239000003596 drug target Substances 0.000 abstract 1
- 238000011321 prophylaxis Methods 0.000 abstract 1
- 230000009261 transgenic effect Effects 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
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- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
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- C—CHEMISTRY; METALLURGY
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- C07K14/4721—Lipocortins
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
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- A01K2267/03—Animal model, e.g. for test or diseases
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- C—CHEMISTRY; METALLURGY
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- C07K2319/00—Fusion polypeptide
- C07K2319/40—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation
- C07K2319/41—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation containing a Myc-tag
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- C12N2830/003—Vector systems having a special element relevant for transcription controllable enhancer/promoter combination inducible enhancer/promoter combination, e.g. hypoxia, iron, transcription factor tet inducible
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Abstract
La presente invención se refiere al uso de p11 como un objetivo de fármaco, así como una herramienta para el diagnóstico, tratamiento y desarrollo de trastornos relacionados con el receptor p11/5-HT. La presente invención se refiere además a animales de eliminación p11, así como animales transgénicos p11 y su uso como modelos para el desarrollo de agentes psicoterapéuticos novedosos, y a métodos de diagnóstico, profilaxis y tratamiento de trastornos relacionado con receptor p11/5-HT.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US81317006P | 2006-06-13 | 2006-06-13 | |
US87873007P | 2007-01-05 | 2007-01-05 | |
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US20100162422A1 (en) * | 2006-06-13 | 2010-06-24 | Per Svenningsson | Novel therapeutic and diagnostic products and methods |
CA2704786C (en) * | 2007-11-02 | 2019-04-09 | Cornell University | Materials and methods for gene mediated therapy of psychiatric disorders |
JP5898970B2 (ja) * | 2012-01-20 | 2016-04-06 | 株式会社日立製作所 | 気分評価システム |
CN104774942A (zh) * | 2015-04-09 | 2015-07-15 | 新乡医学院 | S100A10mRNA在α-干扰素诱导抑郁症中的应用 |
CN109364846B (zh) * | 2018-10-16 | 2021-03-23 | 中子康(武汉)医药科技有限公司 | 电刺激增加生物分子量子能量共性技术的应用 |
CN111990296B (zh) * | 2020-08-06 | 2022-05-10 | 南京新环检测科技有限公司 | 一种适用于评价多种保健食品改善睡眠功效的方法 |
EP4434538A1 (en) | 2023-03-20 | 2024-09-25 | Philipp Koch | Methods of preventing or treating psychiatric diseases through modulation of the plasminogen-plasmin cascade |
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US6506559B1 (en) | 1997-12-23 | 2003-01-14 | Carnegie Institute Of Washington | Genetic inhibition by double-stranded RNA |
JP4310104B2 (ja) * | 2002-09-28 | 2009-08-05 | 英俊 猪子 | マイクロサテライト遺伝多型マーカを用いる遺伝子のマッピング方法 |
US20040142897A1 (en) | 2001-11-28 | 2004-07-22 | Waisman David M. | Compositions and methods for inhibiting tumor growth and metastasis |
JP4421889B2 (ja) * | 2003-01-21 | 2010-02-24 | 独立行政法人理化学研究所 | 慢性関節リウマチの発症危険度を予測する方法 |
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US20120178797A1 (en) | 2012-07-12 |
CN101466410A (zh) | 2009-06-24 |
ES2432759T3 (es) | 2013-12-05 |
ES2649038T3 (es) | 2018-01-09 |
EP2026845A4 (en) | 2010-06-02 |
CA2651846C (en) | 2019-11-12 |
CN101466410B (zh) | 2013-03-06 |
US20150071858A1 (en) | 2015-03-12 |
JP2009544278A (ja) | 2009-12-17 |
CA2651846A1 (en) | 2007-12-21 |
WO2007146372A3 (en) | 2008-11-06 |
EP2659913B1 (en) | 2017-08-02 |
EP2659913A2 (en) | 2013-11-06 |
AU2007258233A1 (en) | 2007-12-21 |
JP2016122005A (ja) | 2016-07-07 |
JP5997104B2 (ja) | 2016-09-28 |
EP2659913A3 (en) | 2014-02-12 |
JP2013223498A (ja) | 2013-10-31 |
US8470548B2 (en) | 2013-06-25 |
KR20090056938A (ko) | 2009-06-03 |
US20130330740A1 (en) | 2013-12-12 |
JP5554564B2 (ja) | 2014-07-23 |
KR20140061552A (ko) | 2014-05-21 |
KR101541668B1 (ko) | 2015-08-03 |
KR101438841B1 (ko) | 2014-09-11 |
EP2026845A2 (en) | 2009-02-25 |
EP2026845B1 (en) | 2013-06-12 |
AU2007258233B2 (en) | 2012-11-22 |
WO2007146372A2 (en) | 2007-12-21 |
US20100162422A1 (en) | 2010-06-24 |
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