MX2008001919A - Proceso para la preparacion de una dispersion estable de particulas submicronicas en un medio acuoso. - Google Patents

Proceso para la preparacion de una dispersion estable de particulas submicronicas en un medio acuoso.

Info

Publication number
MX2008001919A
MX2008001919A MX2008001919A MX2008001919A MX2008001919A MX 2008001919 A MX2008001919 A MX 2008001919A MX 2008001919 A MX2008001919 A MX 2008001919A MX 2008001919 A MX2008001919 A MX 2008001919A MX 2008001919 A MX2008001919 A MX 2008001919A
Authority
MX
Mexico
Prior art keywords
water
inhibitor
process according
substance
particles
Prior art date
Application number
MX2008001919A
Other languages
English (en)
Spanish (es)
Inventor
Lennart Lindfors
Urban Skantze
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of MX2008001919A publication Critical patent/MX2008001919A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/216—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acids having aromatic rings, e.g. benactizyne, clofibrate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4422—1,4-Dihydropyridines, e.g. nifedipine, nicardipine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Dispersion Chemistry (AREA)
  • Emergency Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Colloid Chemistry (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
MX2008001919A 2005-08-12 2006-08-09 Proceso para la preparacion de una dispersion estable de particulas submicronicas en un medio acuoso. MX2008001919A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE0501807 2005-08-12
PCT/SE2006/000933 WO2007021228A1 (en) 2005-08-12 2006-08-09 Process

Publications (1)

Publication Number Publication Date
MX2008001919A true MX2008001919A (es) 2008-03-24

Family

ID=37757817

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2008001919A MX2008001919A (es) 2005-08-12 2006-08-09 Proceso para la preparacion de una dispersion estable de particulas submicronicas en un medio acuoso.

Country Status (13)

Country Link
US (1) US20080193534A1 (https=)
EP (1) EP1915131A4 (https=)
JP (1) JP2009505976A (https=)
KR (1) KR20080033383A (https=)
CN (1) CN101242809A (https=)
AU (1) AU2006280511A1 (https=)
BR (1) BRPI0614904A2 (https=)
CA (1) CA2618468A1 (https=)
IL (1) IL188971A0 (https=)
MX (1) MX2008001919A (https=)
NO (1) NO20081311L (https=)
WO (1) WO2007021228A1 (https=)
ZA (1) ZA200800919B (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008097165A1 (en) * 2007-02-09 2008-08-14 Astrazeneca Ab Process for preparation of a stable dispersion of solid amorphous submicron particles in an aqueous medium
TW200848039A (en) * 2007-02-09 2008-12-16 Astrazeneca Ab Pharmaceutical compositions
US8920682B2 (en) * 2010-03-19 2014-12-30 Eastern Michigan University Nanoparticle dispersions with ionic liquid-based stabilizers
US12414564B2 (en) * 2019-03-27 2025-09-16 Syngenta Crop Protection Ag Fungicide formulations with reduced crystal growth

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4826689A (en) * 1984-05-21 1989-05-02 University Of Rochester Method for making uniformly sized particles from water-insoluble organic compounds
US4832953A (en) * 1987-08-13 1989-05-23 Alza Corporation Method for preventing the formation of a crystalline hydrate in a dispersion of a liquid in a monaqueous matrix
FR2651680B1 (fr) * 1989-09-14 1991-12-27 Medgenix Group Sa Nouveau procede de preparation de microparticules lipidiques.
US5110717A (en) * 1990-12-17 1992-05-05 Eastman Kodak Company Stability improvement of amorphous particle dispersions
US5145684A (en) * 1991-01-25 1992-09-08 Sterling Drug Inc. Surface modified drug nanoparticles
FR2692575B1 (fr) * 1992-06-23 1995-06-30 Sanofi Elf Nouveaux derives du pyrazole, procede pour leur preparation et compositions pharmaceutiques les contenant.
DE4327063A1 (de) * 1993-08-12 1995-02-16 Kirsten Dr Westesen Ubidecarenon-Partikel mit modifizierten physikochemischen Eigenschaften
DE4329446A1 (de) * 1993-09-01 1995-03-02 Basf Ag Verfahren zur Herstellung von feinteiligen Farb- oder Wirkstoffzubereitungen
GB9319129D0 (en) * 1993-09-15 1993-11-03 Dowelanco Ltd Storage and dilution of stable aqueous dispersions
FR2714057B1 (fr) * 1993-12-17 1996-03-08 Sanofi Elf Nouveaux dérivés du 3-pyrazolecarboxamide, procédé pour leur préparation et compositions pharmaceutiques les contenant.
US6458373B1 (en) * 1997-01-07 2002-10-01 Sonus Pharmaceuticals, Inc. Emulsion vehicle for poorly soluble drugs
ATE364374T1 (de) * 1997-08-11 2007-07-15 Pfizer Prod Inc Feste pharmazeutische dispersionen mit erhöhter bioverfügbarkeit
US6375986B1 (en) * 2000-09-21 2002-04-23 Elan Pharma International Ltd. Solid dose nanoparticulate compositions comprising a synergistic combination of a polymeric surface stabilizer and dioctyl sodium sulfosuccinate
US6267989B1 (en) * 1999-03-08 2001-07-31 Klan Pharma International Ltd. Methods for preventing crystal growth and particle aggregation in nanoparticulate compositions
WO2001058869A2 (en) * 2000-02-11 2001-08-16 Bristol-Myers Squibb Company Cannabinoid receptor modulators, their processes of preparation, and use of cannabinoid receptor modulators in treating respiratory and non-respiratory diseases
CA2407027C (en) * 2000-04-20 2011-02-15 Rtp Pharma Inc. Improved water-insoluble drug particle process
CN1254233C (zh) * 2001-08-06 2006-05-03 阿斯特拉曾尼卡有限公司 含有水不溶性的稳定纳米颗粒和赋形剂如中链甘油三酯(mct)的水性分散体
CA2470533A1 (en) * 2002-01-14 2003-07-24 Dow Global Technologies Inc. Drug nanoparticles from template emulsions
ATE395044T1 (de) * 2002-02-01 2008-05-15 Pfizer Prod Inc Pharmazeutische zusammensetzungen amorpher dispersionen von wirkstoffen und lipophiler mikrophasenbildender materialien
US6825209B2 (en) * 2002-04-15 2004-11-30 Research Triangle Institute Compounds having unique CB1 receptor binding selectivity and methods for their production and use
PL372202A1 (en) * 2002-06-11 2005-07-11 Merck Patent Gmbh Modified byrodin 1 with reduced immunogenicity
US7390505B2 (en) * 2003-01-31 2008-06-24 Elan Pharma International, Ltd. Nanoparticulate topiramate formulations
GB0302672D0 (en) * 2003-02-06 2003-03-12 Astrazeneca Ab Pharmaceutical formulations
US20060198856A1 (en) * 2005-03-01 2006-09-07 Keith Whitehead Ibuprofen suspension stabilized with docusate sodium

Also Published As

Publication number Publication date
KR20080033383A (ko) 2008-04-16
ZA200800919B (en) 2008-12-31
WO2007021228A1 (en) 2007-02-22
EP1915131A4 (en) 2012-07-25
US20080193534A1 (en) 2008-08-14
IL188971A0 (en) 2008-08-07
CN101242809A (zh) 2008-08-13
CA2618468A1 (en) 2007-02-22
NO20081311L (no) 2008-05-13
AU2006280511A1 (en) 2007-02-22
BRPI0614904A2 (pt) 2012-12-25
EP1915131A1 (en) 2008-04-30
JP2009505976A (ja) 2009-02-12

Similar Documents

Publication Publication Date Title
CA2456180C (en) Aqueous dispersion comprising stable nanoparticles of a water-insoluble active and an excipient like middle chain triglycerides (mct)
AU2002317409A1 (en) Aqueous dispersion comprising stable nanoparticles of a water-insoluble active and an excipient like middle chain triglycerides (MCT)
NZ537654A (en) Process for the preparation of crystalline nano-particle dispersions
CA2547659A1 (en) Method for preparing nano-scale or amorphous particle using solid fat as a solvent
EP1592451B1 (en) Stable dispersion of solid particles comprising a water-insoluble pyrazine compound
Sin Cheow et al. Towards sustainability: new approaches to nano-drug preparation
MX2008001919A (es) Proceso para la preparacion de una dispersion estable de particulas submicronicas en un medio acuoso.
CA3022777A1 (en) Method for preparing nanoparticle of active ingredient using lipid as lubricant in milling process
CN101605533B (zh) 制备固体非晶亚微米颗粒在水性介质中的稳定分散体的方法
ZA200400847B (en) Aqueous dispersion comprising stable nanoparticles of a water-insoluble active and an excipient like Middle Chain Triglycerides (MCT).
HK1064048B (en) Aqueous dispersion comprising stable nanoparticles of a water-insoluble active and an excipient like middle chain triglycerides (mct)
US20080214611A1 (en) Pharmaceutical Compositions - 659
Rao et al. Evaporative nanocrystallization for enhanced solubility and bioavailability of sulfasalazine
VERMA et al. Indian Journal of Novel Drug Delivery An Official Publication of
Sunil et al. Perspectives in Nanosuspension drug delivery.
ES2292300A1 (es) Procedimiento para la obtencion de un material compuesto.
HK1075199B (en) Process for the preparation of crystalline nano-particle dispersions

Legal Events

Date Code Title Description
FA Abandonment or withdrawal