IL188971A0 - Process for the preparation of a stable dispersion of sub-micron particles in an aqueous medium - Google Patents

Process for the preparation of a stable dispersion of sub-micron particles in an aqueous medium

Info

Publication number
IL188971A0
IL188971A0 IL188971A IL18897108A IL188971A0 IL 188971 A0 IL188971 A0 IL 188971A0 IL 188971 A IL188971 A IL 188971A IL 18897108 A IL18897108 A IL 18897108A IL 188971 A0 IL188971 A0 IL 188971A0
Authority
IL
Israel
Prior art keywords
sub
preparation
aqueous medium
stable dispersion
micron particles
Prior art date
Application number
IL188971A
Other languages
English (en)
Original Assignee
Astrazeneca Ab
Lennart Lindfors
Skantze Urban
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab, Lennart Lindfors, Skantze Urban filed Critical Astrazeneca Ab
Publication of IL188971A0 publication Critical patent/IL188971A0/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/216Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acids having aromatic rings, e.g. benactizyne, clofibrate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/44221,4-Dihydropyridines, e.g. nifedipine, nicardipine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/107Emulsions ; Emulsion preconcentrates; Micelles

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Dispersion Chemistry (AREA)
  • Emergency Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Colloid Chemistry (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
IL188971A 2005-08-12 2008-01-23 Process for the preparation of a stable dispersion of sub-micron particles in an aqueous medium IL188971A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE0501807 2005-08-12
PCT/SE2006/000933 WO2007021228A1 (en) 2005-08-12 2006-08-09 Process

Publications (1)

Publication Number Publication Date
IL188971A0 true IL188971A0 (en) 2008-08-07

Family

ID=37757817

Family Applications (1)

Application Number Title Priority Date Filing Date
IL188971A IL188971A0 (en) 2005-08-12 2008-01-23 Process for the preparation of a stable dispersion of sub-micron particles in an aqueous medium

Country Status (13)

Country Link
US (1) US20080193534A1 (https=)
EP (1) EP1915131A4 (https=)
JP (1) JP2009505976A (https=)
KR (1) KR20080033383A (https=)
CN (1) CN101242809A (https=)
AU (1) AU2006280511A1 (https=)
BR (1) BRPI0614904A2 (https=)
CA (1) CA2618468A1 (https=)
IL (1) IL188971A0 (https=)
MX (1) MX2008001919A (https=)
NO (1) NO20081311L (https=)
WO (1) WO2007021228A1 (https=)
ZA (1) ZA200800919B (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008097165A1 (en) * 2007-02-09 2008-08-14 Astrazeneca Ab Process for preparation of a stable dispersion of solid amorphous submicron particles in an aqueous medium
TW200848039A (en) * 2007-02-09 2008-12-16 Astrazeneca Ab Pharmaceutical compositions
US8920682B2 (en) * 2010-03-19 2014-12-30 Eastern Michigan University Nanoparticle dispersions with ionic liquid-based stabilizers
US12414564B2 (en) * 2019-03-27 2025-09-16 Syngenta Crop Protection Ag Fungicide formulations with reduced crystal growth

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4826689A (en) * 1984-05-21 1989-05-02 University Of Rochester Method for making uniformly sized particles from water-insoluble organic compounds
US4832953A (en) * 1987-08-13 1989-05-23 Alza Corporation Method for preventing the formation of a crystalline hydrate in a dispersion of a liquid in a monaqueous matrix
FR2651680B1 (fr) * 1989-09-14 1991-12-27 Medgenix Group Sa Nouveau procede de preparation de microparticules lipidiques.
US5110717A (en) * 1990-12-17 1992-05-05 Eastman Kodak Company Stability improvement of amorphous particle dispersions
US5145684A (en) * 1991-01-25 1992-09-08 Sterling Drug Inc. Surface modified drug nanoparticles
FR2692575B1 (fr) * 1992-06-23 1995-06-30 Sanofi Elf Nouveaux derives du pyrazole, procede pour leur preparation et compositions pharmaceutiques les contenant.
DE4327063A1 (de) * 1993-08-12 1995-02-16 Kirsten Dr Westesen Ubidecarenon-Partikel mit modifizierten physikochemischen Eigenschaften
DE4329446A1 (de) * 1993-09-01 1995-03-02 Basf Ag Verfahren zur Herstellung von feinteiligen Farb- oder Wirkstoffzubereitungen
GB9319129D0 (en) * 1993-09-15 1993-11-03 Dowelanco Ltd Storage and dilution of stable aqueous dispersions
FR2714057B1 (fr) * 1993-12-17 1996-03-08 Sanofi Elf Nouveaux dérivés du 3-pyrazolecarboxamide, procédé pour leur préparation et compositions pharmaceutiques les contenant.
US6458373B1 (en) * 1997-01-07 2002-10-01 Sonus Pharmaceuticals, Inc. Emulsion vehicle for poorly soluble drugs
ATE364374T1 (de) * 1997-08-11 2007-07-15 Pfizer Prod Inc Feste pharmazeutische dispersionen mit erhöhter bioverfügbarkeit
US6375986B1 (en) * 2000-09-21 2002-04-23 Elan Pharma International Ltd. Solid dose nanoparticulate compositions comprising a synergistic combination of a polymeric surface stabilizer and dioctyl sodium sulfosuccinate
US6267989B1 (en) * 1999-03-08 2001-07-31 Klan Pharma International Ltd. Methods for preventing crystal growth and particle aggregation in nanoparticulate compositions
WO2001058869A2 (en) * 2000-02-11 2001-08-16 Bristol-Myers Squibb Company Cannabinoid receptor modulators, their processes of preparation, and use of cannabinoid receptor modulators in treating respiratory and non-respiratory diseases
CA2407027C (en) * 2000-04-20 2011-02-15 Rtp Pharma Inc. Improved water-insoluble drug particle process
CN1254233C (zh) * 2001-08-06 2006-05-03 阿斯特拉曾尼卡有限公司 含有水不溶性的稳定纳米颗粒和赋形剂如中链甘油三酯(mct)的水性分散体
CA2470533A1 (en) * 2002-01-14 2003-07-24 Dow Global Technologies Inc. Drug nanoparticles from template emulsions
ATE395044T1 (de) * 2002-02-01 2008-05-15 Pfizer Prod Inc Pharmazeutische zusammensetzungen amorpher dispersionen von wirkstoffen und lipophiler mikrophasenbildender materialien
US6825209B2 (en) * 2002-04-15 2004-11-30 Research Triangle Institute Compounds having unique CB1 receptor binding selectivity and methods for their production and use
PL372202A1 (en) * 2002-06-11 2005-07-11 Merck Patent Gmbh Modified byrodin 1 with reduced immunogenicity
US7390505B2 (en) * 2003-01-31 2008-06-24 Elan Pharma International, Ltd. Nanoparticulate topiramate formulations
GB0302672D0 (en) * 2003-02-06 2003-03-12 Astrazeneca Ab Pharmaceutical formulations
US20060198856A1 (en) * 2005-03-01 2006-09-07 Keith Whitehead Ibuprofen suspension stabilized with docusate sodium

Also Published As

Publication number Publication date
KR20080033383A (ko) 2008-04-16
ZA200800919B (en) 2008-12-31
WO2007021228A1 (en) 2007-02-22
EP1915131A4 (en) 2012-07-25
US20080193534A1 (en) 2008-08-14
CN101242809A (zh) 2008-08-13
CA2618468A1 (en) 2007-02-22
NO20081311L (no) 2008-05-13
AU2006280511A1 (en) 2007-02-22
MX2008001919A (es) 2008-03-24
BRPI0614904A2 (pt) 2012-12-25
EP1915131A1 (en) 2008-04-30
JP2009505976A (ja) 2009-02-12

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