MX2007009007A - Derivados de acido aminobutanoico que inhiben carnitina palmitoil transferasa. - Google Patents
Derivados de acido aminobutanoico que inhiben carnitina palmitoil transferasa.Info
- Publication number
- MX2007009007A MX2007009007A MX2007009007A MX2007009007A MX2007009007A MX 2007009007 A MX2007009007 A MX 2007009007A MX 2007009007 A MX2007009007 A MX 2007009007A MX 2007009007 A MX2007009007 A MX 2007009007A MX 2007009007 A MX2007009007 A MX 2007009007A
- Authority
- MX
- Mexico
- Prior art keywords
- compound according
- tetradecylcarbamoyl
- alkyl
- methyl
- compounds
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C275/04—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms
- C07C275/06—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms of an acyclic and saturated carbon skeleton
- C07C275/16—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms of an acyclic and saturated carbon skeleton being further substituted by carboxyl groups
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/17—Amides, e.g. hydroxamic acids having the group >N—C(O)—N< or >N—C(S)—N<, e.g. urea, thiourea, carmustine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
- C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/81—Amides; Imides
- C07D213/82—Amides; Imides in position 3
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Diabetes (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Cardiology (AREA)
- Child & Adolescent Psychology (AREA)
- Hospice & Palliative Care (AREA)
- Heart & Thoracic Surgery (AREA)
- Epidemiology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT000090A ITRM20050090A1 (it) | 2005-03-02 | 2005-03-02 | Derivati dell'acido ammino-butanoico inibitore della cpt. |
| PCT/EP2006/001290 WO2006092204A1 (en) | 2005-03-02 | 2006-02-13 | Derivatives of aminobutanoic acid inhibiting cpt |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2007009007A true MX2007009007A (es) | 2007-09-14 |
Family
ID=36090946
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2007009007A MX2007009007A (es) | 2005-03-02 | 2006-02-13 | Derivados de acido aminobutanoico que inhiben carnitina palmitoil transferasa. |
Country Status (15)
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2927045A1 (en) * | 2006-10-03 | 2008-04-10 | Muthiah Manoharan | Lipid containing formulations |
| US8410150B2 (en) | 2007-03-09 | 2013-04-02 | University Health Network | Inhibitors of carnitine palmitoyltransferase and treating cancer |
| CA2694724C (en) | 2007-08-01 | 2017-09-12 | University Health Network | Cyclic inhibitors of carnitine palmitoyltransferase and treating cancer |
| WO2009132979A1 (en) * | 2008-04-29 | 2009-11-05 | F. Hoffmann-La Roche Ag | 4-trimethylammonio-butyrates as cpt2 inhibitors |
| ES2507089T3 (es) | 2008-04-29 | 2014-10-14 | F. Hoffmann-La Roche Ag | Derivados del ácido 4-dimetilaminobutírico |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1299266B1 (it) * | 1998-05-15 | 2000-02-29 | Sigma Tau Ind Farmaceuti | Inibitori reversibili della carnitina palmitoil trasferasi |
| US6822115B2 (en) * | 1999-06-30 | 2004-11-23 | Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. | Synthesis of (R) and (S)-aminocarnitine, (R) and (S)-4-phosphonium-3-amino-butanoate, (R) and (S) 3,4-diaminobutanoic acid, and their derivatives starting from D- and L-aspartic acid |
| US8410150B2 (en) | 2007-03-09 | 2013-04-02 | University Health Network | Inhibitors of carnitine palmitoyltransferase and treating cancer |
-
2005
- 2005-03-02 IT IT000090A patent/ITRM20050090A1/it unknown
-
2006
- 2006-02-13 CN CNA2006800065461A patent/CN101133019A/zh active Pending
- 2006-02-13 MX MX2007009007A patent/MX2007009007A/es not_active Application Discontinuation
- 2006-02-13 CA CA002599165A patent/CA2599165A1/en not_active Abandoned
- 2006-02-13 JP JP2007557357A patent/JP2008531613A/ja not_active Withdrawn
- 2006-02-13 KR KR1020077022098A patent/KR20070114197A/ko not_active Application Discontinuation
- 2006-02-13 AU AU2006220097A patent/AU2006220097B2/en not_active Ceased
- 2006-02-13 WO PCT/EP2006/001290 patent/WO2006092204A1/en active Application Filing
- 2006-02-13 EA EA200701868A patent/EA200701868A1/ru unknown
- 2006-02-13 US US11/815,068 patent/US20080161395A1/en not_active Abandoned
- 2006-02-13 SG SG201001512-1A patent/SG159569A1/en unknown
- 2006-02-13 EP EP06706901A patent/EP1853556A1/en not_active Withdrawn
- 2006-02-13 BR BRPI0607558-4A patent/BRPI0607558A2/pt not_active IP Right Cessation
- 2006-02-15 TW TW095105107A patent/TW200640842A/zh unknown
- 2006-02-28 AR ARP060100732A patent/AR052677A1/es not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| CN101133019A (zh) | 2008-02-27 |
| ITRM20050090A1 (it) | 2006-09-03 |
| US20080161395A1 (en) | 2008-07-03 |
| SG159569A1 (en) | 2010-03-30 |
| KR20070114197A (ko) | 2007-11-29 |
| BRPI0607558A2 (pt) | 2009-09-15 |
| WO2006092204A1 (en) | 2006-09-08 |
| TW200640842A (en) | 2006-12-01 |
| JP2008531613A (ja) | 2008-08-14 |
| AU2006220097B2 (en) | 2011-07-07 |
| AU2006220097A1 (en) | 2006-09-08 |
| AR052677A1 (es) | 2007-03-28 |
| EA200701868A1 (ru) | 2008-02-28 |
| EP1853556A1 (en) | 2007-11-14 |
| CA2599165A1 (en) | 2006-09-08 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP5127093B2 (ja) | カルニチンパルミトイル−トランスフェラーゼの可逆的阻害活性を有する化合物 | |
| EP3341355B1 (en) | (s)-3-amino-4-(difluoromethylenyl)cyclopent-1-ene-1-carboxylic acid, and related compounds as gaba aminotransferase inactivators for the treatment of epilepsy, addiction and hepatocellular carcinoma | |
| WO2011044327A1 (en) | Substituted phenylcarbamoyl alkylamino arene compounds and n,n'-bis-arylurea compounds | |
| MX2007009007A (es) | Derivados de acido aminobutanoico que inhiben carnitina palmitoil transferasa. | |
| JP2009545549A (ja) | Ｃｐｔ阻害剤としての４−トリメチルアンモニウム−３−アミノブチレートおよび４−トリメチルフォスフォニウム−３−アミノブチレート誘導体 | |
| SU1308196A3 (ru) | Способ получени 5,11-дигидро-11- @ (1-метил-4-пиперидинил)-амино @ -карбонил @ -6 @ -дибенз ( @ , @ )азепин-6-она или его солей | |
| CN106554314B (zh) | 苯甲酰胺类衍生物 | |
| BR112021010728A2 (pt) | Inibidores da descarboxilase para tratamento da doença de parkinson | |
| JP7097369B2 (ja) | 結晶形 | |
| EP3505515B1 (en) | Crystals of cyclic amine derivative and pharmaceutical use thereof | |
| EP0559625A2 (en) | Esters of L-carnitine and acyl L-carnitine endowed with muscle relaxant activityselective on gastrointestinal tract and pharmaceutical compositions containing same | |
| EP2739608B1 (en) | Insulin secretion promoting agents | |
| US11319290B2 (en) | Substituted 3-dialkylaminomethyl-piperidin-4-yl-benzamides and methods of making and using same | |
| CN109810115B (zh) | 异黄酮类化合物及其制备方法与应用 | |
| CN116478050B (zh) | 一种手性芳基丙酸衍生物及其药物组合物和用途 | |
| US4520028A (en) | α-Aminobutyric acid transaminase inhibitors | |
| CN109574986B (zh) | 6-氨基苯并[b]噻吩-2-羧酸衍生物及其在抗癫痫方面的应用 | |
| CN108456207B (zh) | 一种酰胺类衍生物及其在心脑血管方面的应用 | |
| CN108218865B (zh) | 一种酰胺类衍生物及其在心脑血管方面的应用 | |
| WO2023172132A1 (en) | Dhcr24 inhibitory compounds | |
| NO791221L (no) | Fremgangsmaate for fremstilling av benzylidenderivater | |
| CN115887435A (zh) | 长链类化合物及其用途 | |
| JP2020186182A (ja) | 標的蛋白質分解誘導化合物 | |
| CN117916219A (zh) | 一类抗膀胱癌的季胺盐化合物及其应用 | |
| CN113402414A (zh) | 一种苯甲酸衍生物及其制法和药物用途 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA | Abandonment or withdrawal |