MX2007008281A - Preparacion de sales farmaceuticas de compuestos de piperazina. - Google Patents

Preparacion de sales farmaceuticas de compuestos de piperazina.

Info

Publication number
MX2007008281A
MX2007008281A MX2007008281A MX2007008281A MX2007008281A MX 2007008281 A MX2007008281 A MX 2007008281A MX 2007008281 A MX2007008281 A MX 2007008281A MX 2007008281 A MX2007008281 A MX 2007008281A MX 2007008281 A MX2007008281 A MX 2007008281A
Authority
MX
Mexico
Prior art keywords
preparation
pharmaceutical salts
salts
piperazine compounds
rotameric
Prior art date
Application number
MX2007008281A
Other languages
English (en)
Inventor
William Leong
Wenxue Wu
Kevin Klopfer
Sa Bosco D
Feng Liang
Loc Thanh Tran
Hong-Chang Lee
Vijay Sabesen
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Publication of MX2007008281A publication Critical patent/MX2007008281A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

La presente invencion esta orientada en general a un procedimiento para preparar en forma directa sales aceptables para su uso farmaceutico y que estan enriquecidas con respecto a seleccionadas sales rotamericas de un compuesto basico por medio de la eleccion creativa de un acido y de un solvente medio; el procedimiento es particularmente util para la preparacion de rotameros especificos de sales utiles para su uso farmaceutico con la deseada preponderancia de un rotamero.
MX2007008281A 2005-01-06 2006-01-05 Preparacion de sales farmaceuticas de compuestos de piperazina. MX2007008281A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US64191005P 2005-01-06 2005-01-06
PCT/US2006/000261 WO2006074269A2 (en) 2005-01-06 2006-01-05 Preparation of pharmaceutical salts of piperazine compounds

Publications (1)

Publication Number Publication Date
MX2007008281A true MX2007008281A (es) 2007-09-07

Family

ID=36592935

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2007008281A MX2007008281A (es) 2005-01-06 2006-01-05 Preparacion de sales farmaceuticas de compuestos de piperazina.

Country Status (10)

Country Link
US (2) US7521452B2 (es)
EP (1) EP1836190A2 (es)
JP (1) JP2008526862A (es)
CN (1) CN101133048A (es)
AR (1) AR052865A1 (es)
CA (1) CA2594109A1 (es)
MX (1) MX2007008281A (es)
SG (1) SG158858A1 (es)
WO (1) WO2006074269A2 (es)
ZA (1) ZA200705514B (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008526862A (ja) * 2005-01-06 2008-07-24 シェーリング コーポレイション ピペラジン化合物の薬学的な塩の調製
CA2716838C (en) * 2008-02-29 2014-01-07 Schering Corporation Ccr5 antagonists as prophylactics for preventing hiv infection and methods of inhibiting transmission of same

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR0010304A (pt) 1999-05-04 2002-02-13 Schering Corp Derivados de piperazina úteis como antagonistas do ccr5
US6270325B1 (en) * 1999-09-14 2001-08-07 Hsieh Hsin-Mao Magnetically assembled cooling fan
AUPQ887100A0 (en) 2000-07-19 2000-08-10 Dynamic Digital Depth Research Pty Ltd Image processing and encoding techniques
SI1373256T1 (sl) * 2001-03-29 2005-12-31 Schering Corp Antagonisti CCR5, uporabni pri zdravljenju AIDS-a
AU2002346569A1 (en) * 2001-11-29 2003-06-17 Schering Corporation Process for the preparation of compositions having an increased amount of pharmaceutically active salts of rotamers
CA2467555A1 (en) * 2001-11-29 2003-08-14 Schering Corporation Preparation of pharmaceutical salts of 4 ( (z) - (4-bromophenyl) (ethoxyimino) methyl)-1'-( (2,4-dimethyl-1-oxido-3-pyridinyl) carbonyl) -4'-me thyl-1,4' bipiperidine as ccr5-antagonists for the treatment of aids and related hiv infections
JP2008526862A (ja) * 2005-01-06 2008-07-24 シェーリング コーポレイション ピペラジン化合物の薬学的な塩の調製

Also Published As

Publication number Publication date
US20090093496A1 (en) 2009-04-09
WO2006074269A2 (en) 2006-07-13
CA2594109A1 (en) 2006-07-13
CN101133048A (zh) 2008-02-27
US20060241295A1 (en) 2006-10-26
ZA200705514B (en) 2008-09-25
WO2006074269A3 (en) 2006-09-14
JP2008526862A (ja) 2008-07-24
AR052865A1 (es) 2007-04-11
EP1836190A2 (en) 2007-09-26
SG158858A1 (en) 2010-02-26
US7521452B2 (en) 2009-04-21

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