MX2007006043A - Metodo de tratamiento de cancer. - Google Patents

Metodo de tratamiento de cancer.

Info

Publication number
MX2007006043A
MX2007006043A MX2007006043A MX2007006043A MX2007006043A MX 2007006043 A MX2007006043 A MX 2007006043A MX 2007006043 A MX2007006043 A MX 2007006043A MX 2007006043 A MX2007006043 A MX 2007006043A MX 2007006043 A MX2007006043 A MX 2007006043A
Authority
MX
Mexico
Prior art keywords
treatment method
cancer treatment
administration
breast cancer
treating breast
Prior art date
Application number
MX2007006043A
Other languages
English (en)
Inventor
Stephen Rubin
Original Assignee
Smithkline Beecham Cork Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=36588668&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX2007006043(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Smithkline Beecham Cork Ltd filed Critical Smithkline Beecham Cork Ltd
Publication of MX2007006043A publication Critical patent/MX2007006043A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/473—Quinolines; Isoquinolines ortho- or peri-condensed with carbocyclic ring systems, e.g. acridines, phenanthridines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/513—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Se describe un metodo para tratar cancer de seno que tiene metastasis hacia el cerebro en un mamifero, a traves de la administracion de 4-quinazolinaminas y composiciones farmaceuticas que contienen las mismas. En particular, el metodo se refiere a metodos para tratar metastasis en cerebro por cancer de seno, las cuales sobre-expresan erbB2 a traves de la administracion de etil]amino} metil)-2-furil]-4-quinazolinamina de N-{3-cloro-4-[(3-fluorobencil)oxi]fenil}-6-[5-({[2- (metanosulfonil) y sales o solvatos del mismo.
MX2007006043A 2004-12-17 2005-12-16 Metodo de tratamiento de cancer. MX2007006043A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US63705204P 2004-12-17 2004-12-17
PCT/US2005/046350 WO2006066267A2 (en) 2004-12-17 2005-12-16 Cancer treatment method

Publications (1)

Publication Number Publication Date
MX2007006043A true MX2007006043A (es) 2007-06-13

Family

ID=36588668

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2007006043A MX2007006043A (es) 2004-12-17 2005-12-16 Metodo de tratamiento de cancer.

Country Status (14)

Country Link
US (2) US20080306097A1 (es)
EP (1) EP1824492B1 (es)
JP (1) JP5291345B2 (es)
KR (1) KR20070107004A (es)
CN (1) CN101083995A (es)
AU (1) AU2005316238B2 (es)
ES (1) ES2426007T3 (es)
IL (1) IL183059A0 (es)
MX (1) MX2007006043A (es)
NO (1) NO20072631L (es)
NZ (1) NZ555462A (es)
RU (1) RU2007119432A (es)
WO (1) WO2006066267A2 (es)
ZA (1) ZA200705059B (es)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1906185A1 (en) * 2006-09-26 2008-04-02 ProteoSys AG Use of at least one isoform of progesterone receptor membrane component 1 (PGRMC1)
WO2009137714A2 (en) 2008-05-07 2009-11-12 Teva Pharmaceutical Industries Ltd. Forms of lapatinib ditosylate and processes for preparation thereof
EP2158913A1 (en) 2008-08-25 2010-03-03 Ratiopharm GmbH Pharmaceutical composition comprising N-[3-chhloro-4-[(3-fluorophenyl)methoxy]phenyl]6-(5[[[2-(methylsulfonyl)ethyl]amino]methyl]-2-furyl]-4-quinazolinamine
EP2158912A1 (en) 2008-08-25 2010-03-03 Ratiopharm GmbH Pharmaceutical composition comprising N-[3-chhloro-4-[3-fluorophenyl)methoxy)phenyl]6-[5[[[2-(methylsulfonyl)ethyl]amino]methyl]-2-furyl]-4-quinazolinamine
MX2011009498A (es) 2009-03-11 2011-10-14 Ardea Biosciences Inc Combinaciones farmaceuticas que comprenden rdea119/bay 869766 para el tratamiento de canceres especificos.
CN102146075B (zh) * 2010-02-06 2014-04-02 浙江九洲药业股份有限公司 一种喹唑啉化合物的制备方法
US8710221B2 (en) 2010-03-23 2014-04-29 Scinopharm Taiwan, Ltd. Process and intermediates for preparing lapatinib
AU2011232219B2 (en) 2010-03-23 2016-02-04 Scinopharm Taiwan, Ltd. Process and intermediates for preparing lapatinib
CN102344444B (zh) * 2010-07-23 2015-07-01 岑均达 光学纯喹唑啉类化合物
CN102344445B (zh) * 2010-07-23 2015-11-25 岑均达 光学纯喹唑啉类化合物
CN102321076B (zh) * 2011-07-07 2013-08-21 中国科学技术大学 拉帕替尼中间体及其类似物的制备方法
CZ2012712A3 (cs) 2012-10-17 2014-04-30 Zentiva, K.S. Nový způsob výroby klíčového intermediátu výroby lapatinibu
CN106632276B (zh) * 2015-10-28 2021-06-15 上海天慈生物谷生物工程有限公司 一种治疗乳腺癌药物的制备方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RS49779B (sr) * 1998-01-12 2008-06-05 Glaxo Group Limited, Biciklična heteroaromatična jedinjenja kao inhibitori protein tirozin kinaze
JP4458746B2 (ja) * 2001-01-16 2010-04-28 グラクソ グループ リミテッド 癌の治療方法
US20090317383A1 (en) * 2004-06-04 2009-12-24 Berger Mark S Cancer treatment method

Also Published As

Publication number Publication date
CN101083995A (zh) 2007-12-05
EP1824492A4 (en) 2009-10-28
RU2007119432A (ru) 2009-01-27
WO2006066267A3 (en) 2006-12-14
NZ555462A (en) 2009-03-31
WO2006066267A2 (en) 2006-06-22
KR20070107004A (ko) 2007-11-06
NO20072631L (no) 2007-07-02
EP1824492B1 (en) 2013-07-10
IL183059A0 (en) 2007-10-31
AU2005316238B2 (en) 2009-05-07
JP2008524258A (ja) 2008-07-10
US20150283139A1 (en) 2015-10-08
US20080306097A1 (en) 2008-12-11
EP1824492A2 (en) 2007-08-29
ZA200705059B (en) 2009-09-30
AU2005316238A1 (en) 2006-06-22
JP5291345B2 (ja) 2013-09-18
ES2426007T3 (es) 2013-10-18

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