MX2007000576A - Agonistas del receptor nicotinico para el tratamiento de enfermedades inflamatorias. - Google Patents
Agonistas del receptor nicotinico para el tratamiento de enfermedades inflamatorias.Info
- Publication number
- MX2007000576A MX2007000576A MX2007000576A MX2007000576A MX2007000576A MX 2007000576 A MX2007000576 A MX 2007000576A MX 2007000576 A MX2007000576 A MX 2007000576A MX 2007000576 A MX2007000576 A MX 2007000576A MX 2007000576 A MX2007000576 A MX 2007000576A
- Authority
- MX
- Mexico
- Prior art keywords
- receptor agonists
- treatment
- inflammatory diseases
- nicotinic receptor
- analogs
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
- A61K31/221—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin with compounds having an amino group, e.g. acetylcholine, acetylcarnitine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/465—Nicotine; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/16—Central respiratory analeptics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/04—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
- C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
- C07D243/08—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 not condensed with other rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/02—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements
- C07D295/027—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring
- C07D295/033—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring with the ring nitrogen atoms directly attached to carbocyclic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/02—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements
- C07D295/037—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements with quaternary ring nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
- C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
- C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pulmonology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Emergency Medicine (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Immunology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
Esta invencion se relaciona al uso de agonistas del receptor de nicotina o analogos o derivados de los mismos para tratar enfermedades pulmonares inflamatorias. La invencion ademas se relaciona a composiciones farmaceuticas que comprenden agonistas del receptor de nicotina o analogos o derivados de los mismos. Tambien se proporcionan compuestos novedosos de la formula en donde R1, R2, Xa y Ya son como se definen en la presente.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US10/890,987 US20050130990A1 (en) | 2001-03-23 | 2004-07-15 | Nicotinic receptor agonists for the treatment of inflammatory diseases |
PCT/CA2005/001120 WO2006005195A1 (en) | 2004-07-15 | 2005-07-15 | Nicotinic receptor agonists for the treatment of inflammatory diseases |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2007000576A true MX2007000576A (es) | 2007-06-25 |
Family
ID=35783487
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2007000576A MX2007000576A (es) | 2004-07-15 | 2005-07-15 | Agonistas del receptor nicotinico para el tratamiento de enfermedades inflamatorias. |
Country Status (17)
Country | Link |
---|---|
EP (1) | EP1773779B1 (es) |
JP (1) | JP4783787B2 (es) |
KR (1) | KR100860903B1 (es) |
CN (2) | CN101001843B (es) |
AU (1) | AU2005262174C1 (es) |
BR (1) | BRPI0513305A (es) |
CA (1) | CA2573977C (es) |
DK (1) | DK1773779T3 (es) |
ES (1) | ES2445751T3 (es) |
HK (1) | HK1098155A1 (es) |
IL (1) | IL180721A (es) |
MX (1) | MX2007000576A (es) |
NO (1) | NO20070789L (es) |
NZ (1) | NZ553211A (es) |
PL (1) | PL1773779T3 (es) |
RU (1) | RU2414461C2 (es) |
WO (1) | WO2006005195A1 (es) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2341952A1 (en) | 2001-03-23 | 2002-09-23 | Universite Laval | Nicotinic receptor agonists for the treatment of inflammatory pulmonary diseases |
US8557804B2 (en) | 2002-03-25 | 2013-10-15 | Universite Laval | Nicotinic receptor agonists for the treatment of inflammatory diseases |
US8039459B2 (en) | 2004-07-15 | 2011-10-18 | Universite Laval | Nicotinic receptor agonists for the treatment of inflammatory diseases |
WO2008103818A1 (en) * | 2007-02-21 | 2008-08-28 | University Of Louisville Research Foundation | Therapeutic cotinine compositions |
US9944610B2 (en) | 2013-03-13 | 2018-04-17 | UNIVERSITé LAVAL | Preparation and method for use in the treatment of respiratory diseases |
WO2015149178A1 (en) * | 2014-04-03 | 2015-10-08 | UNIVERSITé LAVAL | Method for use of homopiperazinium compounds in the treatment of cancer |
AU2017250514B2 (en) | 2016-04-12 | 2019-12-19 | Arturo Solis Herrera | Compositions and Methods for Treating Nasal and Paranasal Mucosa Diseases with Nicotinic Acetylcholine Receptor Agonists |
KR101976633B1 (ko) | 2017-04-27 | 2019-05-09 | 서울대학교산학협력단 | 폐 섬유증의 예방 또는 치료용 약학적 조성물 |
US20200230213A1 (en) * | 2017-10-03 | 2020-07-23 | The Johns Hopkins University | Lung cell treatments to prevent or treat disease |
KR102115557B1 (ko) | 2018-10-29 | 2020-05-26 | 서울대학교산학협력단 | 폐 섬유증의 예방 또는 치료용 약학적 조성물 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3402039A (en) * | 1966-12-05 | 1968-09-17 | Dow Chemical Co | Piperazinium salts as plant stunting agents |
SE0001075D0 (sv) * | 1999-09-01 | 2000-03-27 | Laszlo Bense | Användning av åtminstone ett nikotinbaserat ämne och/eller ett ur detta ämne framställt ämne för tillverkning av ett medikament samt förfarande för behandling av obstruktiva lungsjukdomar |
CA2441096C (en) * | 2001-03-23 | 2009-06-30 | Universite Laval | Nicotinic receptor agonists for the treatment of inflammatory diseases |
CA2341952A1 (en) * | 2001-03-23 | 2002-09-23 | Universite Laval | Nicotinic receptor agonists for the treatment of inflammatory pulmonary diseases |
FR2852830B1 (fr) * | 2003-03-24 | 2008-04-18 | Oreal | Composition de teinture des fibres keratiniques comprenant un derive de para-phenylenediamine cationique substitue par un cycle diazacyclohexane ou diazacycloheptane |
-
2005
- 2005-07-15 CA CA2573977A patent/CA2573977C/en not_active Expired - Fee Related
- 2005-07-15 MX MX2007000576A patent/MX2007000576A/es active IP Right Grant
- 2005-07-15 KR KR1020077003592A patent/KR100860903B1/ko not_active IP Right Cessation
- 2005-07-15 NZ NZ553211A patent/NZ553211A/en not_active IP Right Cessation
- 2005-07-15 CN CN200580026163.6A patent/CN101001843B/zh not_active Expired - Fee Related
- 2005-07-15 PL PL05764252T patent/PL1773779T3/pl unknown
- 2005-07-15 ES ES05764252.2T patent/ES2445751T3/es active Active
- 2005-07-15 AU AU2005262174A patent/AU2005262174C1/en not_active Ceased
- 2005-07-15 BR BRPI0513305-0A patent/BRPI0513305A/pt not_active IP Right Cessation
- 2005-07-15 WO PCT/CA2005/001120 patent/WO2006005195A1/en active Application Filing
- 2005-07-15 DK DK05764252.2T patent/DK1773779T3/da active
- 2005-07-15 RU RU2007105582/04A patent/RU2414461C2/ru not_active IP Right Cessation
- 2005-07-15 CN CN2012103248870A patent/CN102872022A/zh active Pending
- 2005-07-15 EP EP05764252.2A patent/EP1773779B1/en not_active Not-in-force
- 2005-07-15 JP JP2007520635A patent/JP4783787B2/ja not_active Expired - Fee Related
-
2007
- 2007-01-15 IL IL180721A patent/IL180721A/en not_active IP Right Cessation
- 2007-02-09 NO NO20070789A patent/NO20070789L/no not_active Application Discontinuation
- 2007-05-31 HK HK07105810.0A patent/HK1098155A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
EP1773779B1 (en) | 2013-12-04 |
IL180721A0 (en) | 2007-06-03 |
EP1773779A1 (en) | 2007-04-18 |
AU2005262174A2 (en) | 2006-01-19 |
JP2008505938A (ja) | 2008-02-28 |
KR100860903B1 (ko) | 2008-09-29 |
PL1773779T3 (pl) | 2014-04-30 |
CN101001843A (zh) | 2007-07-18 |
KR20070085207A (ko) | 2007-08-27 |
RU2414461C2 (ru) | 2011-03-20 |
AU2005262174B2 (en) | 2009-10-08 |
AU2005262174C1 (en) | 2010-05-06 |
HK1098155A1 (en) | 2007-07-13 |
ES2445751T3 (es) | 2014-03-05 |
CN101001843B (zh) | 2014-08-27 |
EP1773779A4 (en) | 2009-09-23 |
CA2573977A1 (en) | 2006-01-19 |
NO20070789L (no) | 2007-03-21 |
RU2007105582A (ru) | 2008-08-20 |
IL180721A (en) | 2012-10-31 |
CN102872022A (zh) | 2013-01-16 |
JP4783787B2 (ja) | 2011-09-28 |
NZ553211A (en) | 2010-11-26 |
CA2573977C (en) | 2012-04-10 |
AU2005262174A1 (en) | 2006-01-19 |
DK1773779T3 (da) | 2014-02-10 |
BRPI0513305A (pt) | 2008-05-06 |
WO2006005195A1 (en) | 2006-01-19 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
MX2007000576A (es) | Agonistas del receptor nicotinico para el tratamiento de enfermedades inflamatorias. | |
TW200833675A (en) | Nicotinamide derivatives | |
GEP20084452B (en) | Sulfonamide derivatives for the treatment of diseases | |
MX2009000531A (es) | Derivados heterociclicos fusionados y metodos de uso. | |
ATE453636T1 (de) | Substituierte 2,3-dihydro-1h-isoindol-1-one derivate und anwendungsverfahren | |
EA200700099A1 (ru) | Производные пиридина | |
TW200720260A (en) | Prokineticin 1 receptor antagonists | |
TW200716566A (en) | Prokineticin 2 receptor antagonists | |
GEP20084439B (en) | Nitrogen-containing heterocyclic derivatives and pharmaceutical use thereof | |
TW200716596A (en) | Substituted amide derivatives and methods of use | |
MY159615A (en) | Fused heterocyclic derivatives and methods of use as c-met inhibitors | |
NO20070224L (no) | 2-karbamid-4-fenyltiazolderivater, fremstilling og terapeutisk anvendelse derav | |
NO20072371L (no) | Kinuklidinderivater og deres anvendelse som muskarine M3-reseptorantagonister | |
MY153258A (en) | Pyrazinone derivatives and their use inthe threatment of lung diseases | |
ATE517882T1 (de) | Chinolinderivate | |
ATE440834T1 (de) | Substituierte arylaminderivate und verwendungsverfahren | |
ATE482210T1 (de) | Oxadiazolderivate als s1p1-rezeptor-agonisten | |
ATE404552T1 (de) | Substituierte isochinolinderivate und anwendungsverfahren | |
MX2009006543A (es) | Compuestos heterociclicos y su uso en el tratamiento de la inflamacion, angiogenesis y cancer. | |
NO20082496L (no) | Pyrazinderivater | |
MX2009000169A (es) | Derivados de purinona como agonistas de hm74a. | |
EA200970065A1 (ru) | Производные пиперазинила, предназначенные для лечения заболеваний, опосредованных рецептором gpr38 | |
GEP20135744B (en) | Quinuclidine carbonate derivatives and medicinal compositions containing the same | |
MX2007006387A (es) | Derivados de piridina 3-substituidos como antagonistas h3. | |
GB0524814D0 (en) | Compounds |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG | Grant or registration |