MX180679A - Benzonitrilos substituidos y procedimiento para su preparacion. - Google Patents

Benzonitrilos substituidos y procedimiento para su preparacion.

Info

Publication number
MX180679A
MX180679A MX21553A MX2155390A MX180679A MX 180679 A MX180679 A MX 180679A MX 21553 A MX21553 A MX 21553A MX 2155390 A MX2155390 A MX 2155390A MX 180679 A MX180679 A MX 180679A
Authority
MX
Mexico
Prior art keywords
benzonitrils
substituted
procedure
preparation
tetr
Prior art date
Application number
MX21553A
Other languages
English (en)
Inventor
Marc Lang
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of MX180679A publication Critical patent/MX180679A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D257/04—Five-membered rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Endocrinology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Hydrogenated Pyridines (AREA)
  • Catalysts (AREA)
  • Saccharide Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

Abstract

Se describen compuestos de fórmula (I), en donde Te tr, R, R0, R1 y R2 se definirán en la descripción con propiedades farmacéuticas valiosas y especialmente efectivas contra los tumores. estos compuestos se preparan de manera conocida per se.
MX21553A 1989-07-14 1990-07-12 Benzonitrilos substituidos y procedimiento para su preparacion. MX180679A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH264489 1989-07-14
CH28390 1990-01-30

Publications (1)

Publication Number Publication Date
MX180679A true MX180679A (es) 1996-01-23

Family

ID=25684123

Family Applications (1)

Application Number Title Priority Date Filing Date
MX21553A MX180679A (es) 1989-07-14 1990-07-12 Benzonitrilos substituidos y procedimiento para su preparacion.

Country Status (21)

Country Link
US (1) US5073574A (es)
EP (1) EP0408509B1 (es)
JP (1) JPH0352874A (es)
KR (1) KR910002815A (es)
AT (1) ATE135000T1 (es)
AU (1) AU633333B2 (es)
CA (1) CA2021049A1 (es)
DD (1) DD296483A5 (es)
DE (1) DE59010171D1 (es)
DK (1) DK0408509T3 (es)
ES (1) ES2084687T3 (es)
FI (1) FI97618C (es)
GR (1) GR3019241T3 (es)
HU (1) HU204801B (es)
IE (1) IE71047B1 (es)
IL (1) IL94995A (es)
MX (1) MX180679A (es)
NO (1) NO177961C (es)
NZ (1) NZ234477A (es)
PT (1) PT94681B (es)
ZA (1) ZA905503B (es)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH02276574A (ja) * 1989-04-17 1990-11-13 Gakken Co Ltd ワサビ培養細胞によるペルオキシダーゼ製造法及び培養物からのペルオキシダーゼ精製法
EP0457716A1 (de) * 1990-04-20 1991-11-21 Ciba-Geigy Ag Naphthalinderivate
TW224461B (es) * 1990-09-18 1994-06-01 Ciba Geigy Ag
TW210334B (es) * 1990-12-12 1993-08-01 Ciba Geigy Ag
CH683151A5 (de) * 1991-04-24 1994-01-31 Ciba Geigy Ag Antikonzeption bei weiblichen Primaten ohne Beeinflussung des menstruellen Zyklus.
GB2273704B (en) * 1992-12-16 1997-01-22 Orion Yhtymae Oy Triazolyl diaryl selective aromatase inhibiting compounds
IT1286866B1 (it) * 1996-10-28 1998-07-17 Menarini Farma Ind Composti furano-eterociclici,loro preparazione ed uso come inibitori di aromatasi
KR100370064B1 (ko) * 2000-04-10 2003-01-29 엘지전자 주식회사 광 픽업 장치의 슬라이더 헤드 및 그 제조방법
US20070100149A1 (en) * 2005-11-02 2007-05-03 Palle Venkata Raghavendra A Process for preparing letrozole
US7538230B2 (en) * 2005-11-14 2009-05-26 Chemagis Ltd. Letrozole production process
US7465749B2 (en) * 2005-11-14 2008-12-16 Chemagis, Ltd. Letrozole purification process
CN101597244B (zh) * 2009-07-07 2012-11-07 浙江海翔药业股份有限公司 一种4,4'-二氰基二苯甲酮的制备方法
CA2785898C (en) * 2009-12-31 2018-07-03 Viamet Pharmaceuticals, Inc. Metalloenzyme inhibitor compounds
AU2011237592B2 (en) 2010-04-08 2016-10-27 Emory University Substituted androst-4-ene diones

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3894033A (en) * 1974-05-16 1975-07-08 Pfizer 5-Aryltetrazoles
US4801594A (en) * 1984-06-18 1989-01-31 Eli Lilly And Company Aromatase inhibitors
US4845227A (en) * 1984-06-18 1989-07-04 Eli Lilly And Company Aromatase inhibitors from azoles
US4703053A (en) * 1985-10-28 1987-10-27 Warner-Lambert Company Benzothiophenes and benzofurans and antiallergic use thereof
US4749713A (en) * 1986-03-07 1988-06-07 Ciba-Geigy Corporation Alpha-heterocycle substituted tolunitriles
US4937250A (en) * 1988-03-07 1990-06-26 Ciba-Geigy Corporation Alpha-heterocycle substituted tolunitriles
US4978672A (en) * 1986-03-07 1990-12-18 Ciba-Geigy Corporation Alpha-heterocyclc substituted tolunitriles
US4943574A (en) * 1987-06-01 1990-07-24 Janssen Pharmaceutica N.V. (1H-azol-1-ylmethyl) substituted benzotriazole derivatives and pharmaceutical compositions containing them
NZ224714A (en) * 1987-06-01 1990-03-27 Janssen Pharmaceutica Nv Substituted benzotriazole derivatives and pharmaceutical compositions
US4820723A (en) * 1987-08-14 1989-04-11 Eli Lilly And Company Disubstituted tetrazole leukotriene antagonists and methods for their use thereas
FR2631827B1 (fr) * 1988-05-27 1992-03-27 Delalande Sa Nouveaux derives d'(hetero)aryl-5 tetrazole, leur procede de preparation et leur application en therapeutique

Also Published As

Publication number Publication date
IE902569A1 (en) 1991-02-27
ES2084687T3 (es) 1996-05-16
EP0408509B1 (de) 1996-03-06
NO177961B (no) 1995-09-18
FI97618C (fi) 1997-01-27
NO177961C (no) 1995-12-27
DD296483A5 (de) 1991-12-05
EP0408509A3 (en) 1991-03-20
GR3019241T3 (en) 1996-06-30
IL94995A0 (en) 1991-06-10
NZ234477A (en) 1993-09-27
PT94681A (pt) 1991-03-20
JPH0352874A (ja) 1991-03-07
NO903131D0 (no) 1990-07-13
HUT56555A (en) 1991-09-30
AU5889990A (en) 1991-01-17
CA2021049A1 (en) 1991-01-15
PT94681B (pt) 1997-04-30
EP0408509A2 (de) 1991-01-16
ATE135000T1 (de) 1996-03-15
KR910002815A (ko) 1991-02-26
IE71047B1 (en) 1997-01-15
IL94995A (en) 1994-06-24
US5073574A (en) 1991-12-17
AU633333B2 (en) 1993-01-28
HU904210D0 (en) 1990-12-28
DE59010171D1 (de) 1996-04-11
FI903503A0 (fi) 1990-07-11
HU204801B (en) 1992-02-28
DK0408509T3 (da) 1996-04-01
ZA905503B (en) 1991-03-27
FI97618B (fi) 1996-10-15
NO903131L (no) 1991-01-15

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