MX169931B - Procedimiento para determinar la catividad de serinproteasas inhibidores de serinproteasas - Google Patents

Procedimiento para determinar la catividad de serinproteasas inhibidores de serinproteasas

Info

Publication number
MX169931B
MX169931B MX012128A MX1212888A MX169931B MX 169931 B MX169931 B MX 169931B MX 012128 A MX012128 A MX 012128A MX 1212888 A MX1212888 A MX 1212888A MX 169931 B MX169931 B MX 169931B
Authority
MX
Mexico
Prior art keywords
serinproteasas
inhibitors
cativity
procedure
plasmin
Prior art date
Application number
MX012128A
Other languages
English (en)
Inventor
Thomas Stief
Norberto Heimburger
Original Assignee
Behringwerke Aktienqesellschof
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Behringwerke Aktienqesellschof filed Critical Behringwerke Aktienqesellschof
Publication of MX169931B publication Critical patent/MX169931B/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • C12Q1/37—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving peptidase or proteinase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/56—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving blood clotting factors, e.g. involving thrombin, thromboplastin, fibrinogen
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/81—Protease inhibitors
    • G01N2333/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
    • G01N2333/811—Serine protease (E.C. 3.4.21) inhibitors
    • G01N2333/8121—Serpins
    • G01N2333/8132—Plasminogen activator inhibitors

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Hematology (AREA)
  • Neurosurgery (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

La presente invención se refiere a procedimiento para determinar la actividad de serinproteasas o de inhibidores de serinproteasas en el plasma o en otros líquidos biológicos, caracterizados porque a una muestra que ha de ser investigada en cuanto al contenido de serinproteasas o inhibidores de serinproteasas se le añade por lo menos un agente oxidante y eventualmente por lo menos un detergente.
MX012128A 1987-07-03 1988-07-01 Procedimiento para determinar la catividad de serinproteasas inhibidores de serinproteasas MX169931B (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19873722082 DE3722082A1 (de) 1987-07-03 1987-07-03 Verfahren zur bestimmung der aktivitaet von serinproteasen oder serinproteaseinhibitoren

Publications (1)

Publication Number Publication Date
MX169931B true MX169931B (es) 1993-08-02

Family

ID=6330890

Family Applications (1)

Application Number Title Priority Date Filing Date
MX012128A MX169931B (es) 1987-07-03 1988-07-01 Procedimiento para determinar la catividad de serinproteasas inhibidores de serinproteasas

Country Status (9)

Country Link
US (1) US5057414A (es)
EP (1) EP0297597B1 (es)
JP (1) JP2676792B2 (es)
AT (1) ATE129525T1 (es)
AU (1) AU613053B2 (es)
CA (1) CA1338681C (es)
DE (2) DE3722082A1 (es)
ES (1) ES2079350T3 (es)
MX (1) MX169931B (es)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3705744A1 (de) * 1987-02-23 1988-09-01 Behringwerke Ag Verfahren zur funktionellen bestimmung von protein c-inhibitor
US5248596A (en) * 1987-02-25 1993-09-28 Miles Inc. Method of detecting proteolytically modified antithrombin
DE3819923A1 (de) * 1988-06-11 1989-12-21 Behringwerke Ag Fibrin(ogen)derivate, verfahren zu ihrer herstellung und ihre verwendung
DE3838529A1 (de) * 1988-11-14 1990-05-17 Behringwerke Ag Globaltest zur erfassung der hauptkomponenten des fibrinolysesystems
DE3843422A1 (de) * 1988-12-23 1990-06-28 Behringwerke Ag Verfahren zur bestimmung der plasminogenaktivator-aktivitaet in alpha-2-antiplasmin-haltigen proben
DE3929329A1 (de) * 1989-09-04 1991-03-07 Behringwerke Ag Stabilisierungsmittel zur verbesserung der wiederfindung von gerinnungsfaktoren in blutproben
DE4016978A1 (de) * 1990-05-25 1991-11-28 Behringwerke Ag Verfahren zum nachweis von plasminogen-aktivatoren, deren inhibitoren oder stimulatoren
JPH09504719A (ja) * 1993-11-03 1997-05-13 クラリオン、ファーマシューティカルズ、インコーポレイテッド 止血パッチ
US5639726A (en) * 1994-09-30 1997-06-17 The Regents Of The University Of Michigan Peptide mediated enhancement of thrombolysis methods and compositions
US6403092B1 (en) 1998-04-01 2002-06-11 Duke University Immune response modulator alpha-2 macroglobulin complex
CA2383358A1 (en) * 1999-08-31 2001-03-08 Board Of Regents, The University Of Texas System Methods and compositions of a novel serine protease inhibitor
DE10116586B4 (de) * 2001-04-03 2005-07-21 Stief, Thomas, Dr.med. Testsystem zur Bestimmung der Hämostaseaktivierung von biologischen Flüssigkeiten
JP3990972B2 (ja) * 2001-11-20 2007-10-17 有限会社 キック 血管再狭窄防止薬及び該防止薬がコーティングされた血管内埋め込み器具
US20070286854A1 (en) 2004-04-28 2007-12-13 Bayer Healthcare Ag Diagnostics And Therapeutics For Diseases Associated With Dipeptidyl-Peptidase 1 (Dpp1)
DE102004025780B4 (de) * 2004-05-26 2008-04-03 Stief, Thomas, Dr.med. Verfahren zur Anti-Limulus-Faktoren-unabhängigen Bestimmung der Lipopolysaccharid- und/oder Lipid-A- und/oder Glukan-Reaktivität, dafür geeignetes Testsystem sowie dessen Verwendung
EP2484775A1 (de) * 2011-02-07 2012-08-08 Siemens Healthcare Diagnostics Products GmbH Heparin-insensitives Verfahren zur Bestimmung von direkten Gerinnungsfaktorinhibitoren

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4493891A (en) * 1982-07-27 1985-01-15 University Of Georgia Research Foundation, Inc. Determination of oxidized α-1-proteinase inhibitor in serum or plasma
DE3512909A1 (de) * 1985-04-11 1986-10-23 Behringwerke Ag, 3550 Marburg Verfahren zur bestimmung von plasminogenaktivatoren (pa)
DE3537708A1 (de) * 1985-10-23 1987-04-23 Boehringer Mannheim Gmbh Verfahren zur aktivierung von t-pa nach expression in prokaryonten
US5102787A (en) * 1987-07-10 1992-04-07 Miho Sasamata Method, device and kit for measurement of tissue plasminogen activator activity

Also Published As

Publication number Publication date
ATE129525T1 (de) 1995-11-15
AU613053B2 (en) 1991-07-25
ES2079350T3 (es) 1996-01-16
CA1338681C (en) 1996-10-29
EP0297597A2 (de) 1989-01-04
EP0297597A3 (en) 1990-10-03
AU1861588A (en) 1989-01-05
JP2676792B2 (ja) 1997-11-17
EP0297597B1 (de) 1995-10-25
JPS6430599A (en) 1989-02-01
DE3722082A1 (de) 1989-01-12
DE3854611D1 (de) 1995-11-30
US5057414A (en) 1991-10-15

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