MD749F1 - Process for synthesis of cyanocobalamine by the propionic acid bacteries - Google Patents

Process for synthesis of cyanocobalamine by the propionic acid bacteries

Info

Publication number
MD749F1
MD749F1 MD960166A MD960166A MD749F1 MD 749 F1 MD749 F1 MD 749F1 MD 960166 A MD960166 A MD 960166A MD 960166 A MD960166 A MD 960166A MD 749 F1 MD749 F1 MD 749F1
Authority
MD
Moldova
Prior art keywords
cyanocobalamine
synthesis
bacteries
propionic acid
cobalt
Prior art date
Application number
MD960166A
Other languages
Romanian (ro)
Other versions
MD749G2 (en
Inventor
Valeriu Rudic
Svetlana Codreanu
Liliana Cepoi
Aurelian Gulea
Ghenadie Novitchi
Original Assignee
Univ De Stat Din Moldova
Inst De Microbiologie Al Acade
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ De Stat Din Moldova, Inst De Microbiologie Al Acade filed Critical Univ De Stat Din Moldova
Priority to MD96-0166A priority Critical patent/MD749G2/en
Publication of MD749F1 publication Critical patent/MD749F1/en
Publication of MD749G2 publication Critical patent/MD749G2/en

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  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

Process for synthesis of cyanocobalamine by the propionic acid bacteries in accordance with the invention forsees the microorganisms cultivation in two phases at the facultative aerobic conditions in the nutritive medium consisting of (g/l): maize extract - 60,0; glucose - 35,0; ammonium sulfate - 3,5; 5,6-dimethylbenzimidazole - 0,02; Porphyridi- um cruentum extract - 0,6; zinc benzoate - 0,0075 and tetrahydrate nickel(II) picolinate - 0,0075, in which on the third day of cultivation the coordination compound of diaminodichlorethylendiamine cobalt(III) nitrate as cobalt sourse in the quantity of 0,009 is added. The technical result of the invention consists in the stability increasing of the cyanocobalamine synthesis process.
MD96-0166A 1996-07-11 1996-07-11 Process for cyanocobalamine synthesis by propionic acid bacteria MD749G2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
MD96-0166A MD749G2 (en) 1996-07-11 1996-07-11 Process for cyanocobalamine synthesis by propionic acid bacteria

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
MD96-0166A MD749G2 (en) 1996-07-11 1996-07-11 Process for cyanocobalamine synthesis by propionic acid bacteria

Publications (2)

Publication Number Publication Date
MD749F1 true MD749F1 (en) 1997-06-30
MD749G2 MD749G2 (en) 1998-02-28

Family

ID=19738874

Family Applications (1)

Application Number Title Priority Date Filing Date
MD96-0166A MD749G2 (en) 1996-07-11 1996-07-11 Process for cyanocobalamine synthesis by propionic acid bacteria

Country Status (1)

Country Link
MD (1) MD749G2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MD2313C2 (en) * 2001-05-25 2004-05-31 Институт Микробиологии И Биотехнологии Академии Наук Молдовы Process for vitamin B12 obtaining
MD4278C1 (en) * 2013-04-30 2014-10-31 Институт Химии Академии Наук Молдовы Compound bis{bis(dimethylglyoximato)chloro}-µ-3-formylpiridineisonicotinoylhydrazone-di-cobalt(III) and process for cultivation of microalga Porphyridium cruentum with its use

Also Published As

Publication number Publication date
MD749G2 (en) 1998-02-28

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Legal Events

Date Code Title Description
FG3A Granted patent for invention
IF99 Valid patent on 19990615

Free format text: EXPIRES: 20160711