MD72C2 - The method of obtaining chinolyncar borxylic acids or its salts which can be used in pharmaceutics - Google Patents
The method of obtaining chinolyncar borxylic acids or its salts which can be used in pharmaceuticsInfo
- Publication number
- MD72C2 MD72C2 MD94-0132A MD940132A MD72C2 MD 72 C2 MD72 C2 MD 72C2 MD 940132 A MD940132 A MD 940132A MD 72 C2 MD72 C2 MD 72C2
- Authority
- MD
- Moldova
- Prior art keywords
- salts
- obtaining
- acid
- pharmaceutics
- medium
- Prior art date
Links
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
The Method of obtaining chinolyncarborxylic acids or its salts which can be used in pharmaceuticsThe invention relates to heterociclic substances, particularly to obtaining chynolyncarboxyl with the general formulain which R is piperazinyl, 4-methylpiperazinyl, 4-ethylpiperazinyl, or its salts which can be used in pharmaceutics and are active from antibacterial point of view and used in medicine. The Aim of the invention is to encrease the efficiency of the special product and to reduce the time of processing, to ensure at the same time a good selectivity. The synthesis is done by the reaction of appropriate derivatives of chinolyn with the general formulain which R2 and R3 are halogene, C2-C6 alkyloxid group with the appropriate derivatives of piperazini with the general formula R4-N-CH2-CH2-NH7-CH2 is CH3 or C2H5 at the temperature of 90-110°C in a solvent medium with a subsequent hydrolysis, separating the special product in the form of an acid or its salts. It is a good idea to as a solvent in an sulfoxid and hydrolysis in an acid medium or alkalyn (NaOH). It is useful to use a medium to fix an acid as an example the excess of piperazyne with the formula above indicated.Taking into account all these conditions it is possible to encrease the efficiency of the process.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HU871505A HU198709B (en) | 1987-04-08 | 1987-04-08 | Process for producing quinoline-carboxylic acid derivatives |
| PCT/HU1988/000019 WO1988007993A1 (en) | 1987-04-08 | 1988-04-08 | Process for the preparation of quinoline carboxylic acids |
| SU884613033A SU1701110A3 (en) | 1987-04-08 | 1988-12-07 | Method for preparation of quinoline carboxylic acid or theirs pharmaceutically acceptable salts |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MD72B1 MD72B1 (en) | 1994-10-31 |
| MD72C2 true MD72C2 (en) | 1995-01-31 |
Family
ID=26317377
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MD94-0132A MD72C2 (en) | 1987-04-08 | 1988-04-08 | The method of obtaining chinolyncar borxylic acids or its salts which can be used in pharmaceutics |
Country Status (2)
| Country | Link |
|---|---|
| LT (1) | LT2190B (en) |
| MD (1) | MD72C2 (en) |
-
1988
- 1988-04-08 MD MD94-0132A patent/MD72C2/en active IP Right Grant
-
1993
- 1993-06-12 LT LTRP647A patent/LT2190B/en not_active IP Right Cessation
Non-Patent Citations (1)
| Title |
|---|
| Brevet DE nr. 3142854, Int. cl. C 07 D 401/04, 1983. * |
Also Published As
| Publication number | Publication date |
|---|---|
| LT2190B (en) | 1993-10-15 |
| MD72B1 (en) | 1994-10-31 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| FI906438A (en) | Process for the preparation of novel therapeutically useful A-nor-steroid-3-carboxylic acid derivatives | |
| IT1206587B (en) | PROCESS FOR THE PRODUCTION OF ACETIC ACID. | |
| ES2056059T3 (en) | A METHOD FOR PREPARING CRYSTALLINE CEPHADROXYL MONOHYDRATE. | |
| DK412287D0 (en) | PROCEDURE FOR PREPARING 1-ETHYL-6-FLUORO-7- (4- SUBSTITUTIONALLY SUBSTITUTED PIPERAZINO) -4-OXO-1,4-DIHYDRO-QUINOLINE-3-CARBOXYLIC ACID DERIVATIVES AND THE PRESENT PRODUCT USE | |
| BG50389A3 (en) | A process for the production of delta 1,4-3-keto c21-semiester sieroids | |
| MD72C2 (en) | The method of obtaining chinolyncar borxylic acids or its salts which can be used in pharmaceutics | |
| DK166384C (en) | METHOD OF ANALOGUE FOR THE PREPARATION OF (-) - 15-DEOXY PERGUALING AND PHARMACEUTICAL ACCEPTABLE ACID ADDITION SALTS AND INTERMEDIATE PRODUCTS | |
| HUT37116A (en) | Process for production of phenil-alanin derivatives | |
| DE3687100D1 (en) | CLAVAME DERIVATIVES, PRODUCTION AND INTERMEDIATE PRODUCTS. | |
| GB1505020A (en) | Substituted 2-phenylimino-thiazolines a process for their preparation and their use as ectoparasiticides | |
| AR241137A2 (en) | Novel allylic amines | |
| JPS527985A (en) | Process for preparing penicillanic acid derivatives | |
| GB1343942A (en) | Procedure for obtaining 6-amino-penicillan-acid | |
| JPS51138664A (en) | Process for preparing 4-exo-hydroxy-endo-tri cyclo 95.2.2.02,6)-undeca-8-ene | |
| JPS5331683A (en) | Novel process for preparation of alpha-amino acid derivatives | |
| JPS51138602A (en) | Process for preparing alpha-hydrazino carboxylic acids | |
| JPS5721387A (en) | Preparation of oxazolidinone derivative | |
| JPS55136281A (en) | Xanthine derivative | |
| IT1054501B (en) | PROCESS FOR THE PREPARATION OF ESTERS OF ACID I.4 NAFTALENDI CARBOSSILICO | |
| JPS51136658A (en) | Process for preparation of 2-naphthoic acid derivatives | |
| JPS51115489A (en) | Method for preparing antibiotics | |
| JPS5227757A (en) | Preparation of 6-aminomethylnaphthalene derivatives | |
| DE2966347D1 (en) | Clavulanic acid derivatives and process for their preparation | |
| JPS5231029A (en) | Process for preparation of triuret | |
| GB1506913A (en) | Process for the preparation of 2-phenylamino-2-imidazoline derivatives |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG4A | Patent for invention issued | ||
| IF99 | Valid patent on 19990615 |
Free format text: EXPIRES: 20080407 |