MD706G2 - Способ получения 2-алкил-6-метил-N- (1'-метокси-2'-пропил)- анилинов и их хлорацетанилидов - Google Patents
Способ получения 2-алкил-6-метил-N- (1'-метокси-2'-пропил)- анилинов и их хлорацетанилидов Download PDFInfo
- Publication number
- MD706G2 MD706G2 MD94-0035A MD940035A MD706G2 MD 706 G2 MD706 G2 MD 706G2 MD 940035 A MD940035 A MD 940035A MD 706 G2 MD706 G2 MD 706G2
- Authority
- MD
- Moldova
- Prior art keywords
- anilines
- alkyl
- methyl
- preparation
- chloracetanilides
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 4
- 238000002360 preparation method Methods 0.000 title abstract 3
- VONWPEXRCLHKRJ-UHFFFAOYSA-N 2-chloro-n-phenylacetamide Chemical class ClCC(=O)NC1=CC=CC=C1 VONWPEXRCLHKRJ-UHFFFAOYSA-N 0.000 title abstract 2
- 239000003054 catalyst Substances 0.000 abstract 2
- CUZLJOLBIRPEFB-UHFFFAOYSA-N 1-methoxypropan-2-one Chemical compound COCC(C)=O CUZLJOLBIRPEFB-UHFFFAOYSA-N 0.000 abstract 1
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 229910052799 carbon Inorganic materials 0.000 abstract 1
- 230000003197 catalytic effect Effects 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 239000000706 filtrate Substances 0.000 abstract 1
- 238000001914 filtration Methods 0.000 abstract 1
- 239000012467 final product Substances 0.000 abstract 1
- 239000004009 herbicide Substances 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 238000005984 hydrogenation reaction Methods 0.000 abstract 1
- 239000012299 nitrogen atmosphere Substances 0.000 abstract 1
- 239000011541 reaction mixture Substances 0.000 abstract 1
- 238000005932 reductive alkylation reaction Methods 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Landscapes
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
Изобретение относится к области химии, в частности, к способам получения 2-алкил-6-метил-N-(1'-метокси-2'-пропил)-анилинов и их хлорацетанилидов.Способ осуществляют путем каталитического восстановительного алкилирования, где один моль эквивалент метоксиацетона реагирует с одним моль эквивалентом 2-алкил-6-метил-анилином без дополнительного растворителя в присутствии Pt-C катализатора, кислого кокатализатора под давлением водорода в пределах 2х105 - 1х106 Па при t 20 - 80оС. Реакционная смесь содержит воду с начала реакции и после гидрирования добавляют основание, затем катализатор отделяют фильтрованием под азотом и рециклируют, а целевой продукт выделяют из фильтрата. Способ, в частности, может быть использован при получении N-замещенных хлорацетанилидных гербицидов.Технический результат заключается в улучшении экологических и экономических показателей проведения способа.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US99803092A | 1992-12-29 | 1992-12-29 | |
| US08/168,034 US5430188A (en) | 1992-12-29 | 1993-12-15 | Process for the preparation of 2-alkyl-6-methyl-N-(1'-methoxy-2'-propyl)-aniline and a process for the preparation of their chloracetanilides |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| MD940035A MD940035A (ro) | 1995-06-30 |
| MD706F2 MD706F2 (en) | 1997-04-30 |
| MD706G2 true MD706G2 (ru) | 1998-02-28 |
Family
ID=26863745
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MD94-0035A MD706G2 (ru) | 1992-12-29 | 1993-12-16 | Способ получения 2-алкил-6-метил-N- (1'-метокси-2'-пропил)- анилинов и их хлорацетанилидов |
Country Status (1)
| Country | Link |
|---|---|
| MD (1) | MD706G2 (ru) |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3937730A (en) * | 1972-06-06 | 1976-02-10 | Ciba-Geigy Corporation | Plant growth regulating agent |
| CS270548B1 (sk) * | 1989-01-20 | 1990-07-12 | Beska Emanuel | Sposob pripravy 2-atyl-6-metyl-N-/l'- -metoxy-2'-propyl/ anilinu |
-
1993
- 1993-12-16 MD MD94-0035A patent/MD706G2/ru active IP Right Grant
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3937730A (en) * | 1972-06-06 | 1976-02-10 | Ciba-Geigy Corporation | Plant growth regulating agent |
| CS270548B1 (sk) * | 1989-01-20 | 1990-07-12 | Beska Emanuel | Sposob pripravy 2-atyl-6-metyl-N-/l'- -metoxy-2'-propyl/ anilinu |
Also Published As
| Publication number | Publication date |
|---|---|
| MD706F2 (en) | 1997-04-30 |
| MD940035A (ro) | 1995-06-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| CHPR | Change of proprietorship |
Free format text: NOVARTIS AG, CH |
|
| FG3A | Granted patent for invention | ||
| IF99 | Valid patent on 19990615 |
Free format text: EXPIRES: 20131216 |
|
| MK4A | Patent for invention expired |