MD675Z - Metodă de prevenire a reflexelor patologice în timpul manipulărilor operatorii - Google Patents
Metodă de prevenire a reflexelor patologice în timpul manipulărilor operatorii Download PDFInfo
- Publication number
- MD675Z MD675Z MDS20130051A MDS20130051A MD675Z MD 675 Z MD675 Z MD 675Z MD S20130051 A MDS20130051 A MD S20130051A MD S20130051 A MDS20130051 A MD S20130051A MD 675 Z MD675 Z MD 675Z
- Authority
- MD
- Moldova
- Prior art keywords
- prevention
- dose
- pathological
- manipulations
- during surgical
- Prior art date
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- 230000001575 pathological effect Effects 0.000 title claims abstract description 12
- 238000000034 method Methods 0.000 title claims description 11
- 230000011514 reflex Effects 0.000 title claims description 9
- 230000002265 prevention Effects 0.000 title description 4
- 230000000472 traumatic effect Effects 0.000 claims abstract description 9
- 229950009336 azamethonium bromide Drugs 0.000 claims abstract description 4
- UPCIBFUJJLCOQG-UHFFFAOYSA-L ethyl-[2-[2-[ethyl(dimethyl)azaniumyl]ethyl-methylamino]ethyl]-dimethylazanium;dibromide Chemical compound [Br-].[Br-].CC[N+](C)(C)CCN(C)CC[N+](C)(C)CC UPCIBFUJJLCOQG-UHFFFAOYSA-L 0.000 claims abstract description 4
- 238000011477 surgical intervention Methods 0.000 claims description 8
- 206010002091 Anaesthesia Diseases 0.000 abstract description 4
- 230000037005 anaesthesia Effects 0.000 abstract description 4
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract description 4
- 239000003814 drug Substances 0.000 abstract description 4
- 230000009471 action Effects 0.000 description 7
- 230000036772 blood pressure Effects 0.000 description 6
- NHWGPUVJQFTOQX-UHFFFAOYSA-N ethyl-[2-[2-[ethyl(dimethyl)azaniumyl]ethyl-methylamino]ethyl]-dimethylazanium Chemical compound CC[N+](C)(C)CCN(C)CC[N+](C)(C)CC NHWGPUVJQFTOQX-UHFFFAOYSA-N 0.000 description 6
- 230000000004 hemodynamic effect Effects 0.000 description 6
- 230000006641 stabilisation Effects 0.000 description 4
- 238000011105 stabilization Methods 0.000 description 4
- 208000010444 Acidosis Diseases 0.000 description 3
- 210000000748 cardiovascular system Anatomy 0.000 description 3
- 238000011161 development Methods 0.000 description 3
- 208000035475 disorder Diseases 0.000 description 3
- 230000000574 ganglionic effect Effects 0.000 description 3
- 201000001421 hyperglycemia Diseases 0.000 description 3
- 238000001802 infusion Methods 0.000 description 3
- 230000007774 longterm Effects 0.000 description 3
- 208000030159 metabolic disease Diseases 0.000 description 3
- 230000036284 oxygen consumption Effects 0.000 description 3
- 206010020660 Hyperlactacidaemia Diseases 0.000 description 2
- 208000001953 Hypotension Diseases 0.000 description 2
- 206010027417 Metabolic acidosis Diseases 0.000 description 2
- 229940079593 drug Drugs 0.000 description 2
- 230000002526 effect on cardiovascular system Effects 0.000 description 2
- 230000005284 excitation Effects 0.000 description 2
- 239000003457 ganglion blocking agent Substances 0.000 description 2
- 230000036543 hypotension Effects 0.000 description 2
- 210000005036 nerve Anatomy 0.000 description 2
- 230000007383 nerve stimulation Effects 0.000 description 2
- 210000000653 nervous system Anatomy 0.000 description 2
- 230000000392 somatic effect Effects 0.000 description 2
- SFLSHLFXELFNJZ-QMMMGPOBSA-N (-)-norepinephrine Chemical compound NC[C@H](O)C1=CC=C(O)C(O)=C1 SFLSHLFXELFNJZ-QMMMGPOBSA-N 0.000 description 1
- JOYRKODLDBILNP-UHFFFAOYSA-N Ethyl urethane Chemical compound CCOC(N)=O JOYRKODLDBILNP-UHFFFAOYSA-N 0.000 description 1
- 241000282326 Felis catus Species 0.000 description 1
- 206010021118 Hypotonia Diseases 0.000 description 1
- 208000007379 Muscle Hypotonia Diseases 0.000 description 1
- 208000001871 Tachycardia Diseases 0.000 description 1
- 206010044541 Traumatic shock Diseases 0.000 description 1
- 230000007950 acidosis Effects 0.000 description 1
- 208000026545 acidosis disease Diseases 0.000 description 1
- 230000004913 activation Effects 0.000 description 1
- 239000000464 adrenergic agent Substances 0.000 description 1
- 206010003119 arrhythmia Diseases 0.000 description 1
- 230000006793 arrhythmia Effects 0.000 description 1
- 206010007625 cardiogenic shock Diseases 0.000 description 1
- 150000003943 catecholamines Chemical class 0.000 description 1
- 238000012937 correction Methods 0.000 description 1
- 230000002638 denervation Effects 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 238000002695 general anesthesia Methods 0.000 description 1
- 208000014674 injury Diseases 0.000 description 1
- 238000001990 intravenous administration Methods 0.000 description 1
- 230000002503 metabolic effect Effects 0.000 description 1
- 230000004089 microcirculation Effects 0.000 description 1
- 229960002748 norepinephrine Drugs 0.000 description 1
- SFLSHLFXELFNJZ-UHFFFAOYSA-N norepinephrine Natural products NCC(O)C1=CC=C(O)C(O)=C1 SFLSHLFXELFNJZ-UHFFFAOYSA-N 0.000 description 1
- 230000002093 peripheral effect Effects 0.000 description 1
- 230000000144 pharmacologic effect Effects 0.000 description 1
- 238000009101 premedication Methods 0.000 description 1
- 238000004321 preservation Methods 0.000 description 1
- 210000003497 sciatic nerve Anatomy 0.000 description 1
- 230000001502 supplementing effect Effects 0.000 description 1
- 230000009885 systemic effect Effects 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 230000008733 trauma Effects 0.000 description 1
- 210000001186 vagus nerve Anatomy 0.000 description 1
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- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| MDS20130051A MD675Z (ro) | 2013-03-15 | 2013-03-15 | Metodă de prevenire a reflexelor patologice în timpul manipulărilor operatorii |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| MDS20130051A MD675Z (ro) | 2013-03-15 | 2013-03-15 | Metodă de prevenire a reflexelor patologice în timpul manipulărilor operatorii |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MD675Y MD675Y (en) | 2013-09-30 |
| MD675Z true MD675Z (ro) | 2014-04-30 |
Family
ID=49301207
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MDS20130051A MD675Z (ro) | 2013-03-15 | 2013-03-15 | Metodă de prevenire a reflexelor patologice în timpul manipulărilor operatorii |
Country Status (1)
| Country | Link |
|---|---|
| MD (1) | MD675Z (mo) |
Citations (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MD263C2 (ro) * | 1995-03-01 | 1995-12-31 | Виктор ГИКАВЫЙ | Remediu cu acţiune antihipotensivă "IZOTURON" |
| MD586C2 (ro) * | 1995-05-25 | 1997-03-31 | Государственный Медицинский И Фармацевтический Университет "Nicolae Testemitanu" Республики Молдова | Substanţă medicamentoasă cu acţiune antihipotensivă "Difetur" |
| MD1123F1 (ro) * | 1997-03-25 | 1998-12-31 | Firma Svetskii & Co | Malaxor cu tobă cu rotire reversibilă |
| MD1138C2 (ro) * | 1997-02-17 | 1999-07-31 | Государственный Медицинский И Фармацевтический Университет "Nicolae Testemitanu" Республики Молдова | Izopropilfosfit-S-izopropilizotiuroniu- substanţă cu acţiune hipertensivă |
| MD1431G2 (ro) * | 1998-01-16 | 2001-02-28 | Государственный Медицинский И Фармацевтический Университет "Nicolae Testemitanu" Республики Молдова | Remedii antihipotensive |
| RU2200552C1 (ru) * | 2001-07-18 | 2003-03-20 | ГУ Научно-исследовательский институт экспериментальной медицины РАМН | Способ защиты сердечно-сосудистой системы в процессе операции реваскуляризации миокарда на работающем сердце |
| MD2066G2 (ro) * | 2002-07-10 | 2003-09-30 | Государственный Медицинский И Фармацевтический Университет "Nicolae Testemitanu" Республики Молдова | Remediu antihipertensiv |
| MD2228G2 (ro) * | 2003-01-21 | 2004-02-29 | Государственный Медицинский И Фармацевтический Университет "Nicolae Testemitanu" Республики Молдова | Utilizarea derivaţiilor izotiouronici în tratamentul şi profilaxia atoniei intestinale |
-
2013
- 2013-03-15 MD MDS20130051A patent/MD675Z/ro not_active IP Right Cessation
Patent Citations (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MD263C2 (ro) * | 1995-03-01 | 1995-12-31 | Виктор ГИКАВЫЙ | Remediu cu acţiune antihipotensivă "IZOTURON" |
| MD586C2 (ro) * | 1995-05-25 | 1997-03-31 | Государственный Медицинский И Фармацевтический Университет "Nicolae Testemitanu" Республики Молдова | Substanţă medicamentoasă cu acţiune antihipotensivă "Difetur" |
| MD1138C2 (ro) * | 1997-02-17 | 1999-07-31 | Государственный Медицинский И Фармацевтический Университет "Nicolae Testemitanu" Республики Молдова | Izopropilfosfit-S-izopropilizotiuroniu- substanţă cu acţiune hipertensivă |
| MD1123F1 (ro) * | 1997-03-25 | 1998-12-31 | Firma Svetskii & Co | Malaxor cu tobă cu rotire reversibilă |
| MD1431G2 (ro) * | 1998-01-16 | 2001-02-28 | Государственный Медицинский И Фармацевтический Университет "Nicolae Testemitanu" Республики Молдова | Remedii antihipotensive |
| RU2200552C1 (ru) * | 2001-07-18 | 2003-03-20 | ГУ Научно-исследовательский институт экспериментальной медицины РАМН | Способ защиты сердечно-сосудистой системы в процессе операции реваскуляризации миокарда на работающем сердце |
| MD2066G2 (ro) * | 2002-07-10 | 2003-09-30 | Государственный Медицинский И Фармацевтический Университет "Nicolae Testemitanu" Республики Молдова | Remediu antihipertensiv |
| MD2228G2 (ro) * | 2003-01-21 | 2004-02-29 | Государственный Медицинский И Фармацевтический Университет "Nicolae Testemitanu" Республики Молдова | Utilizarea derivaţiilor izotiouronici în tratamentul şi profilaxia atoniei intestinale |
Non-Patent Citations (2)
| Title |
|---|
| Виноградов В.М. Новые пути лекарственной профилактики и терапии травматического и кардиогенного шока. Автрореф. диссертации. Ленинград, 1965 * |
| Гикавый В.И. Применение этирона при ганглионарном блоке без гипотонии в эксперименте. Здравохранение.Кишинёв, 1970, I, с. 47-50 * |
Also Published As
| Publication number | Publication date |
|---|---|
| MD675Y (en) | 2013-09-30 |
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| Date | Code | Title | Description |
|---|---|---|---|
| FG9Y | Short term patent issued | ||
| KA4Y | Short-term patent lapsed due to non-payment of fees (with right of restoration) |