MD4296C1 - Preparation from Tenebrio molitor larvae with antioxidant activity, process for its preparation and pharmaceutical product on its base - Google Patents

Preparation from Tenebrio molitor larvae with antioxidant activity, process for its preparation and pharmaceutical product on its base

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Publication number
MD4296C1
MD4296C1 MDA20120131A MD20120131A MD4296C1 MD 4296 C1 MD4296 C1 MD 4296C1 MD A20120131 A MDA20120131 A MD A20120131A MD 20120131 A MD20120131 A MD 20120131A MD 4296 C1 MD4296 C1 MD 4296C1
Authority
MD
Moldova
Prior art keywords
preparation
tenebrio molitor
larvae
molitor larvae
pharmaceutical product
Prior art date
Application number
MDA20120131A
Other languages
Romanian (ro)
Russian (ru)
Other versions
MD4296B1 (en
Inventor
Вячеслав ЧУХРИЙ
Original Assignee
Вячеслав ЧУХРИЙ
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Вячеслав ЧУХРИЙ filed Critical Вячеслав ЧУХРИЙ
Priority to MDA20120131A priority Critical patent/MD4296C1/en
Publication of MD4296B1 publication Critical patent/MD4296B1/en
Publication of MD4296C1 publication Critical patent/MD4296C1/en

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  • Medicines Containing Plant Substances (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)

Abstract

The invention relates to the pharmaceutical field, namely to a preparation from Tenebrio molitor larvae with antioxidant activity, a process for its preparation and a pharmaceutical product on its base.The preparation derived from the biomass of Tenebrio molitor larvae, according to the invention, comprises: lyophilized hydroalcoholic extract - 45…80% and vaseline oil - the rest, and manifests activity of inhibiting the peroxidation of lipoproteins IC50% of16 mg/ml and the nitroxide radical IC50% of20 mg/ml.The process for producing the preparation, according to the invention, consists in that Tenebrio molitor larvae are grown on an artificial nutrient medium, then are collected the last age larvae, are washed, disinfected with ultraviolet rays, frozen-thawed and homogenized. From the homogenized biomass is carried out the aqueous extraction for 60…90 min, followed by 70% ethanol extraction, the extracts are concentrated by vacuum evaporation, are combined, lyophilized and mixed with vaseline oil.The pharmaceutical product with antioxidant activity in the form of rectal suppositories comprises, per one suppository with the mass of 2 g: preparation derived from Tenebrio molitor larvae in vaseline oil - 0.25 g and semisynthetic glycerides - 1.75 g
MDA20120131A 2012-12-28 2012-12-28 Preparation from Tenebrio molitor larvae with antioxidant activity, process for its preparation and pharmaceutical product on its base MD4296C1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
MDA20120131A MD4296C1 (en) 2012-12-28 2012-12-28 Preparation from Tenebrio molitor larvae with antioxidant activity, process for its preparation and pharmaceutical product on its base

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
MDA20120131A MD4296C1 (en) 2012-12-28 2012-12-28 Preparation from Tenebrio molitor larvae with antioxidant activity, process for its preparation and pharmaceutical product on its base

Publications (2)

Publication Number Publication Date
MD4296B1 MD4296B1 (en) 2014-08-31
MD4296C1 true MD4296C1 (en) 2015-03-31

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Family Applications (1)

Application Number Title Priority Date Filing Date
MDA20120131A MD4296C1 (en) 2012-12-28 2012-12-28 Preparation from Tenebrio molitor larvae with antioxidant activity, process for its preparation and pharmaceutical product on its base

Country Status (1)

Country Link
MD (1) MD4296C1 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MD1004Z (en) * 2015-04-10 2016-09-30 Виталие ГИКАВЫЙ Method for the treatment of infravesical obstruction caused by benign prostatic hyperplasia

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MD4713C1 (en) 2018-07-19 2021-04-30 Чеслав ЧУХРИЙ Process for producing an active complex of Lymantria dispar larvae

Citations (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2672605A1 (en) * 1991-02-11 1992-08-14 Ferent Maurice PROCESS FOR THE EXTRACTION OF A BIOLOGICAL SUBSTANCE FROM LEPIDOPTERA LARVAE AND SUBSTANCE OBTAINED.
RU2038086C1 (en) * 1991-03-26 1995-06-27 Спиридонов Николай Алексеевич Method for extracting biologically active product from wax moth larvae
JP2004155679A (en) * 2002-11-05 2004-06-03 Kadoriile Nishida:Kk Preparation for external use
MD2764F1 (en) * 2004-07-28 2005-05-31 Universitatea De Stat De Medicina Si Farmacie "Nicolae Testemitanu" Din Republica Moldova Entomologic hepatoprotective preparation
MD2788F1 (en) * 2004-07-28 2005-06-30 Universitatea De Stat De Medicina Si Farmacie "Nicolae Testemitanu" Din Republica Moldova Entomologic anti-inflammatory and antioxidant preparation
MD2789F1 (en) * 2004-07-28 2005-06-30 Universitatea De Stat De Medicina Si Farmacie "Nicolae Testemitanu" Din Republica Moldova Entomologic antioxidant and immunomodulating preparation
MD2787F1 (en) * 2004-07-28 2005-06-30 Universitatea De Stat De Medicina Si Farmacie "Nicolae Testemitanu" Din Republica Moldova Entomologic hepatoprotective and immunomodulating preparation
CN101120701A (en) * 2007-08-06 2008-02-13 杨琳 Method for preparing tenebrio molitorl edible oil
CN101204230A (en) * 2006-12-21 2008-06-25 陈德国 Further processing for tenebrio molitor and uses thereof
KR20080103509A (en) * 2006-01-13 2008-11-27 주식회사유한양행 A method of separating a peptidoglycan recognition protein from a hemolymph of tenebrio molitor larvae
RO122332B1 (en) * 2003-08-25 2009-04-30 Mircea CIUHRII Pharmaceutical composition as suppositories or ovules, for the treatment of hemorrhoids, prostatic adenoma and uterine fibroma and process for preparing the same
KR20100032553A (en) * 2008-09-18 2010-03-26 대한민국(농촌진흥청장) A composition containing silkworm excreta extracts for treatment of atopic dermatitis
CN101199315B (en) * 2007-11-05 2011-08-31 陈跃辉 Tenebrio molitor source biological feed additive and its preparation method
CN102321147A (en) * 2011-09-08 2012-01-18 金振喜 Method for extracting tenebrio molitor protein of fiber for producing wig
CN102422974A (en) * 2011-10-28 2012-04-25 山东省农业科学院农产品研究所 Method for preparing tenebrio molitor protein powder by enzymolysis
CN102697013A (en) * 2012-06-25 2012-10-03 天津春发生物科技集团有限公司 Tenebrio molitor larva enzymatic hydrolysate and preparation method thereof
CN102697020A (en) * 2012-06-25 2012-10-03 天津春发生物科技集团有限公司 Pork-flavored essence and preparation method thereof
CN102726702A (en) * 2012-06-25 2012-10-17 天津春发生物科技集团有限公司 Chicken flavor essence and preparation method thereof
CN102210407B (en) * 2011-05-23 2013-06-05 华南农业大学 Economic insect tenebrio molitor feed formula, preparation method and application thereof
CN103262940A (en) * 2013-06-14 2013-08-28 北京宇宙龙养生科技有限公司 Tenebrio molitor compound protein product and preparation method thereof

Patent Citations (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2672605A1 (en) * 1991-02-11 1992-08-14 Ferent Maurice PROCESS FOR THE EXTRACTION OF A BIOLOGICAL SUBSTANCE FROM LEPIDOPTERA LARVAE AND SUBSTANCE OBTAINED.
RU2038086C1 (en) * 1991-03-26 1995-06-27 Спиридонов Николай Алексеевич Method for extracting biologically active product from wax moth larvae
JP2004155679A (en) * 2002-11-05 2004-06-03 Kadoriile Nishida:Kk Preparation for external use
RO122332B1 (en) * 2003-08-25 2009-04-30 Mircea CIUHRII Pharmaceutical composition as suppositories or ovules, for the treatment of hemorrhoids, prostatic adenoma and uterine fibroma and process for preparing the same
MD2764F1 (en) * 2004-07-28 2005-05-31 Universitatea De Stat De Medicina Si Farmacie "Nicolae Testemitanu" Din Republica Moldova Entomologic hepatoprotective preparation
MD2788F1 (en) * 2004-07-28 2005-06-30 Universitatea De Stat De Medicina Si Farmacie "Nicolae Testemitanu" Din Republica Moldova Entomologic anti-inflammatory and antioxidant preparation
MD2789F1 (en) * 2004-07-28 2005-06-30 Universitatea De Stat De Medicina Si Farmacie "Nicolae Testemitanu" Din Republica Moldova Entomologic antioxidant and immunomodulating preparation
MD2787F1 (en) * 2004-07-28 2005-06-30 Universitatea De Stat De Medicina Si Farmacie "Nicolae Testemitanu" Din Republica Moldova Entomologic hepatoprotective and immunomodulating preparation
MD2788G2 (en) * 2004-07-28 2006-01-31 Государственный Медицинский И Фармацевтический Университет "Nicolae Testemitanu" Республики Молдова Entomologic anti-inflammatory and antioxidant preparation
KR20080103509A (en) * 2006-01-13 2008-11-27 주식회사유한양행 A method of separating a peptidoglycan recognition protein from a hemolymph of tenebrio molitor larvae
CA2636194C (en) * 2006-01-13 2013-07-23 Yuhan Corporation A method of separating a peptidoglycan recognition protein from a hemolymph of tenebrio molitor larvae
CN101204230A (en) * 2006-12-21 2008-06-25 陈德国 Further processing for tenebrio molitor and uses thereof
CN101120701A (en) * 2007-08-06 2008-02-13 杨琳 Method for preparing tenebrio molitorl edible oil
CN101199315B (en) * 2007-11-05 2011-08-31 陈跃辉 Tenebrio molitor source biological feed additive and its preparation method
KR20100032553A (en) * 2008-09-18 2010-03-26 대한민국(농촌진흥청장) A composition containing silkworm excreta extracts for treatment of atopic dermatitis
CN102210407B (en) * 2011-05-23 2013-06-05 华南农业大学 Economic insect tenebrio molitor feed formula, preparation method and application thereof
CN102321147A (en) * 2011-09-08 2012-01-18 金振喜 Method for extracting tenebrio molitor protein of fiber for producing wig
CN102422974A (en) * 2011-10-28 2012-04-25 山东省农业科学院农产品研究所 Method for preparing tenebrio molitor protein powder by enzymolysis
CN102697013A (en) * 2012-06-25 2012-10-03 天津春发生物科技集团有限公司 Tenebrio molitor larva enzymatic hydrolysate and preparation method thereof
CN102697020A (en) * 2012-06-25 2012-10-03 天津春发生物科技集团有限公司 Pork-flavored essence and preparation method thereof
CN102726702A (en) * 2012-06-25 2012-10-17 天津春发生物科技集团有限公司 Chicken flavor essence and preparation method thereof
CN103262940A (en) * 2013-06-14 2013-08-28 北京宇宙龙养生科技有限公司 Tenebrio molitor compound protein product and preparation method thereof

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Ciuhrii V. Biotehnologia obţinerii formei medicamentoase pentru tratarea hiperplaziei benigne de prostată. Teza de doctor în biologie, Chişinău, 2010, 129 p. *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MD1004Z (en) * 2015-04-10 2016-09-30 Виталие ГИКАВЫЙ Method for the treatment of infravesical obstruction caused by benign prostatic hyperplasia

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Publication number Publication date
MD4296B1 (en) 2014-08-31

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FG4A Patent for invention issued