MD3942F1 - Iron and cobalt complexes with 2-furoic acid possessing antituberculous properties - Google Patents

Iron and cobalt complexes with 2-furoic acid possessing antituberculous properties

Info

Publication number
MD3942F1
MD3942F1 MDA20090003A MD20090003A MD3942F1 MD 3942 F1 MD3942 F1 MD 3942F1 MD A20090003 A MDA20090003 A MD A20090003A MD 20090003 A MD20090003 A MD 20090003A MD 3942 F1 MD3942 F1 MD 3942F1
Authority
MD
Moldova
Prior art keywords
iron
properties
antituberculous
cobalt complexes
furoic acid
Prior art date
Application number
MDA20090003A
Other languages
Romanian (ro)
Other versions
MD3942C2 (en
Inventor
Silvia Melnic
Denis Prodius
Sergiu Sova
Constantin Turta
Original Assignee
Institutul De Chimie Al Academiei De Stiinte A Moldovei
Universitatea De Stat Din Moldova
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Institutul De Chimie Al Academiei De Stiinte A Moldovei, Universitatea De Stat Din Moldova filed Critical Institutul De Chimie Al Academiei De Stiinte A Moldovei
Priority to MDA20090003A priority Critical patent/MD3942C2/en
Publication of MD3942F1 publication Critical patent/MD3942F1/en
Publication of MD3942C2 publication Critical patent/MD3942C2/en

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Inventia se refera la complecsii fierului si cobaltului cu acidul furan-2-carboxilic, cu activitate antituberculoasa. Esenta inventiei consta in sinteza compusilor complecsi heteronucleari (I-III), cu formula:[Fe2CoO(C4H3OCOO)6(L1)(L2)2], undeL1=THF L2= H2O (I)L1=DMFA L2= H2O (II)L1=L2=3Cl-Py (III),care manifesta proprietati de inhibare a cresterii tulpinilor Mycobacterium tuberculosis.The invention relates to iron and cobalt complexes with furan-2-carboxylic acid, with antituberculosis activity. The essence of the invention consists in the synthesis of heteronuclear complex compounds (I-III), with the formula: [Fe2CoO (C4H3OCOO) 6 (L1) (L2) 2], where L1 = THF L2 = H2O (I) L1 = DMFA L2 = H2O (II) L1 = L2 = 3Cl-Py (III), which exhibits inhibitory properties of Mycobacterium tuberculosis strain growth.

MDA20090003A 2009-01-22 2009-01-22 Iron and cobalt complexes with 2-furoic acid possessing antituberculous properties MD3942C2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
MDA20090003A MD3942C2 (en) 2009-01-22 2009-01-22 Iron and cobalt complexes with 2-furoic acid possessing antituberculous properties

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
MDA20090003A MD3942C2 (en) 2009-01-22 2009-01-22 Iron and cobalt complexes with 2-furoic acid possessing antituberculous properties

Publications (2)

Publication Number Publication Date
MD3942F1 true MD3942F1 (en) 2009-07-31
MD3942C2 MD3942C2 (en) 2010-02-28

Family

ID=40941132

Family Applications (1)

Application Number Title Priority Date Filing Date
MDA20090003A MD3942C2 (en) 2009-01-22 2009-01-22 Iron and cobalt complexes with 2-furoic acid possessing antituberculous properties

Country Status (1)

Country Link
MD (1) MD3942C2 (en)

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE7804098L (en) * 1977-04-20 1978-10-21 R & Z Vermoegensverw Gmbh PEPTIDE COMPLEX FROM DNA-CONTAINING ORGANISMS
MD675C2 (en) * 1995-03-06 1998-02-28 Государственный Медицинский И Фармацевтический Университет "Nicolae Testemitanu" Республики Молдова The cobalt's complexes with antimicrobic activity and process for manufacturing of them
MD346G2 (en) * 1995-04-12 1996-09-30 Государственный Университет Молд0 Picoliden-4-isonicotino-yl-hydrazone dyhidrate with tuberculostatic activity
US20020068761A1 (en) * 1999-10-04 2002-06-06 Bernstein Lawrence R. Gallium complexes of 3-hydroxy-4-pyrones to treat mycobacterial infections
MD2146C2 (en) * 2001-07-12 2003-10-31 Государственный Университет Молд0 Dielectric materials on base of heteronuclear coordinative combinations of cobalt (III) and bismuth (III)
UA44385U (en) * 2004-02-04 2009-10-12 Винай Рамакант Сапте Oral cyclodextrin composition
MD2786G2 (en) * 2004-05-11 2006-02-28 Государственный Университет Молд0 Inhibitors of human myeloid leukemia on base of heteronuclear coordinative compounds of cobalt(III) and bismuth(III)
EP1996611A1 (en) * 2006-03-23 2008-12-03 Centre National de la Recherche Scientifique Complexes of nadp with the protein maba of mycobacterium tuberculosis or with mutants thereof, and their uses for designing and screening antibiotics
CA2652454C (en) * 2006-05-24 2013-04-30 Gen-Probe Incorporated Compositions, methods and kits for determining the presence of mycobacterium tuberculosis complex organisms in a test sample

Also Published As

Publication number Publication date
MD3942C2 (en) 2010-02-28

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Legal Events

Date Code Title Description
FG4A Patent for invention issued
TK4A Erratum in official gazette in regard to patent for invention

Free format text: RECTIFICATION IN INID 13

KA4A Patent for invention lapsed due to non-payment of fees (with right of restoration)
MM4A Patent for invention definitely lapsed due to non-payment of fees