MD3898613T2 - Compuși anticancer - Google Patents
Compuși anticancerInfo
- Publication number
- MD3898613T2 MD3898613T2 MDE20211044T MDE20211044T MD3898613T2 MD 3898613 T2 MD3898613 T2 MD 3898613T2 MD E20211044 T MDE20211044 T MD E20211044T MD E20211044 T MDE20211044 T MD E20211044T MD 3898613 T2 MD3898613 T2 MD 3898613T2
- Authority
- MD
- Moldova
- Prior art keywords
- anticancer compounds
- anticancer
- compounds
- derivatives
- formula
- Prior art date
Links
- 230000001093 anti-cancer Effects 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 title abstract 2
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/26—Acyclic or carbocyclic radicals, substituted by hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/427—Thiazoles not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/661—Phosphorus acids or esters thereof not having P—C bonds, e.g. fosfosal, dichlorvos, malathion or mevinphos
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/7056—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing five-membered rings with nitrogen as a ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/12—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains three hetero rings
- C07D493/14—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/06—Phosphorus compounds without P—C bonds
- C07F9/08—Esters of oxyacids of phosphorus
- C07F9/141—Esters of phosphorous acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/24—Heterocyclic radicals containing oxygen or sulfur as ring hetero atom
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Molecular Biology (AREA)
- Epidemiology (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Peptides Or Proteins (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pyridine Compounds (AREA)
- Saccharide Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
Sunt furnizaţi compuşi anticancer cu formula I şi derivaţi ai acestora.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP18382934 | 2018-12-17 | ||
| PCT/EP2019/085544 WO2020127194A1 (en) | 2018-12-17 | 2019-12-17 | Anticancer compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MD3898613T2 true MD3898613T2 (ro) | 2023-12-31 |
Family
ID=64746491
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MDE20211044T MD3898613T2 (ro) | 2018-12-17 | 2019-12-17 | Compuși anticancer |
Country Status (34)
| Country | Link |
|---|---|
| US (1) | US20220056021A1 (ro) |
| EP (1) | EP3898613B1 (ro) |
| JP (1) | JP7525493B2 (ro) |
| KR (1) | KR20210104791A (ro) |
| CN (1) | CN113166102A (ro) |
| AR (1) | AR116911A1 (ro) |
| AU (1) | AU2019400736A1 (ro) |
| BR (1) | BR112021011304A2 (ro) |
| CA (1) | CA3123744A1 (ro) |
| CL (1) | CL2021001584A1 (ro) |
| CO (1) | CO2021009339A2 (ro) |
| DK (1) | DK3898613T3 (ro) |
| EA (1) | EA202191714A1 (ro) |
| EC (1) | ECSP21050732A (ro) |
| ES (1) | ES2961370T3 (ro) |
| FI (1) | FI3898613T3 (ro) |
| HR (1) | HRP20231286T1 (ro) |
| HU (1) | HUE064529T2 (ro) |
| IL (1) | IL284011B1 (ro) |
| JO (1) | JOP20210139A1 (ro) |
| LT (1) | LT3898613T (ro) |
| MA (1) | MA54520B1 (ro) |
| MD (1) | MD3898613T2 (ro) |
| MX (1) | MX2021007276A (ro) |
| PH (1) | PH12021551438A1 (ro) |
| PL (1) | PL3898613T3 (ro) |
| PT (1) | PT3898613T (ro) |
| RS (1) | RS64727B1 (ro) |
| SG (1) | SG11202105992SA (ro) |
| SI (1) | SI3898613T1 (ro) |
| TW (1) | TWI830837B (ro) |
| UY (1) | UY38516A (ro) |
| WO (1) | WO2020127194A1 (ro) |
| ZA (1) | ZA202104675B (ro) |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AUPR320701A0 (en) | 2001-02-20 | 2001-03-15 | Kim, Jonghee | The new cancer therapeutic agent with a thiopeptides |
| AU2004263509A1 (en) | 2003-08-08 | 2005-02-17 | Merck Sharp & Dohme Corp. | Tetrahydropyran heterocyclic cyclopentyl heteroaryl modulators of chemokine receptor activity |
| GB0523098D0 (en) * | 2005-11-14 | 2005-12-21 | Pharma Mar Sa | Antitumoral compounds |
| AU2008317352A1 (en) * | 2007-10-24 | 2009-04-30 | Merck Sharp & Dohme Corp. | Heterocycle amide T-type calcium channel antagonists |
| MX2011012712A (es) * | 2009-05-29 | 2012-01-30 | Raqualia Pharma Inc | Derivados de carboxamida sustituidos con arilo como bloqueadores del canal de calcio o sodio. |
-
2019
- 2019-12-17 PT PT198323214T patent/PT3898613T/pt unknown
- 2019-12-17 SI SI201930639T patent/SI3898613T1/sl unknown
- 2019-12-17 ES ES19832321T patent/ES2961370T3/es active Active
- 2019-12-17 MD MDE20211044T patent/MD3898613T2/ro unknown
- 2019-12-17 US US17/414,946 patent/US20220056021A1/en active Pending
- 2019-12-17 DK DK19832321.4T patent/DK3898613T3/da active
- 2019-12-17 MA MA54520A patent/MA54520B1/fr unknown
- 2019-12-17 AR ARP190103695A patent/AR116911A1/es unknown
- 2019-12-17 HR HRP20231286TT patent/HRP20231286T1/hr unknown
- 2019-12-17 FI FIEP19832321.4T patent/FI3898613T3/fi active
- 2019-12-17 EP EP19832321.4A patent/EP3898613B1/en active Active
- 2019-12-17 EA EA202191714A patent/EA202191714A1/ru unknown
- 2019-12-17 CN CN201980082135.8A patent/CN113166102A/zh active Pending
- 2019-12-17 JO JOP/2021/0139A patent/JOP20210139A1/ar unknown
- 2019-12-17 IL IL284011A patent/IL284011B1/en unknown
- 2019-12-17 PL PL19832321.4T patent/PL3898613T3/pl unknown
- 2019-12-17 MX MX2021007276A patent/MX2021007276A/es unknown
- 2019-12-17 HU HUE19832321A patent/HUE064529T2/hu unknown
- 2019-12-17 BR BR112021011304-5A patent/BR112021011304A2/pt unknown
- 2019-12-17 UY UY0001038516A patent/UY38516A/es unknown
- 2019-12-17 RS RS20230949A patent/RS64727B1/sr unknown
- 2019-12-17 WO PCT/EP2019/085544 patent/WO2020127194A1/en active Application Filing
- 2019-12-17 SG SG11202105992SA patent/SG11202105992SA/en unknown
- 2019-12-17 TW TW108146189A patent/TWI830837B/zh active
- 2019-12-17 AU AU2019400736A patent/AU2019400736A1/en active Pending
- 2019-12-17 KR KR1020217022034A patent/KR20210104791A/ko unknown
- 2019-12-17 CA CA3123744A patent/CA3123744A1/en active Pending
- 2019-12-17 LT LTEPPCT/EP2019/085544T patent/LT3898613T/lt unknown
- 2019-12-17 JP JP2021534773A patent/JP7525493B2/ja active Active
-
2021
- 2021-06-16 CL CL2021001584A patent/CL2021001584A1/es unknown
- 2021-06-17 PH PH12021551438A patent/PH12021551438A1/en unknown
- 2021-07-05 ZA ZA2021/04675A patent/ZA202104675B/en unknown
- 2021-07-08 EC ECSENADI202150732A patent/ECSP21050732A/es unknown
- 2021-07-16 CO CONC2021/0009339A patent/CO2021009339A2/es unknown
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