MD3773715T2 - Mirikizumab în tratamentul colitei ulcerative - Google Patents

Mirikizumab în tratamentul colitei ulcerative Download PDF

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Publication number
MD3773715T2
MD3773715T2 MDE20210135T MDE20210135T MD3773715T2 MD 3773715 T2 MD3773715 T2 MD 3773715T2 MD E20210135 T MDE20210135 T MD E20210135T MD E20210135 T MDE20210135 T MD E20210135T MD 3773715 T2 MD3773715 T2 MD 3773715T2
Authority
MD
Moldova
Prior art keywords
mirikizumab
patients
dose
week
induction
Prior art date
Application number
MDE20210135T
Other languages
English (en)
Romanian (ro)
Inventor
James Benedict Canavan
Stuart William Friedrich
Kathryn Ann Krueger
Catherine Milch
Jay Lawrence Tuttle
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of MD3773715T2 publication Critical patent/MD3773715T2/ro

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244Interleukins [IL]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/545Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
MDE20210135T 2018-03-30 2019-03-28 Mirikizumab în tratamentul colitei ulcerative MD3773715T2 (ro)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201862650314P 2018-03-30 2018-03-30
PCT/US2019/024633 WO2019191464A1 (en) 2018-03-30 2019-03-28 Methods of treating ulcerative colitis

Publications (1)

Publication Number Publication Date
MD3773715T2 true MD3773715T2 (ro) 2024-10-31

Family

ID=66429483

Family Applications (1)

Application Number Title Priority Date Filing Date
MDE20210135T MD3773715T2 (ro) 2018-03-30 2019-03-28 Mirikizumab în tratamentul colitei ulcerative

Country Status (29)

Country Link
US (2) US12152072B2 (enExample)
EP (2) EP3773715B1 (enExample)
JP (4) JP7119114B2 (enExample)
KR (1) KR102552693B1 (enExample)
CN (1) CN111936165A (enExample)
AU (2) AU2019243283C1 (enExample)
BR (1) BR112020018099A2 (enExample)
CA (1) CA3095297A1 (enExample)
DK (1) DK3773715T3 (enExample)
EA (1) EA202091989A1 (enExample)
ES (1) ES2983809T3 (enExample)
FI (1) FI3773715T3 (enExample)
HR (1) HRP20240904T1 (enExample)
HU (1) HUE067445T2 (enExample)
IL (2) IL277514B2 (enExample)
LT (1) LT3773715T (enExample)
MA (1) MA52216B1 (enExample)
MD (1) MD3773715T2 (enExample)
MX (1) MX2020010269A (enExample)
MY (1) MY202368A (enExample)
PL (1) PL3773715T3 (enExample)
PT (1) PT3773715T (enExample)
RS (1) RS65661B1 (enExample)
SG (1) SG11202009526RA (enExample)
SI (1) SI3773715T1 (enExample)
TW (2) TWI837532B (enExample)
UA (1) UA128578C2 (enExample)
WO (1) WO2019191464A1 (enExample)
ZA (1) ZA202005388B (enExample)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2020279987A1 (en) 2019-05-23 2021-11-18 Janssen Biotech, Inc. Method of treating inflammatory bowel disease with a combination therapy of antibodies to IL-23 and TNF alpha
KR20220141847A (ko) * 2020-02-14 2022-10-20 얀센 바이오테크 인코포레이티드 항-il12/il23 항체로 궤양성 결장염을 치료하는 안전하고 효과적인 방법
CA3183927A1 (en) 2020-05-21 2021-11-25 Janssen Biotech, Inc. Method of treating inflammatory bowel disease with a combination therapy of antibodies to il-23 and tnf alpha
JP7423815B2 (ja) * 2020-10-20 2024-01-29 セトラスホールディングス株式会社 治験管理装置、治験管理方法、治験管理プログラム及び治験管理システム
TW202241506A (zh) * 2021-01-06 2022-11-01 美商艾伯維有限公司 治療克羅恩氏病及潰瘍性結腸炎之方法
JP2024520202A (ja) * 2021-05-20 2024-05-22 ヤンセン バイオテツク,インコーポレーテツド Il-23に対する抗体及びtnfアルファに対する抗体の組み合わせ療法を用いた炎症性腸疾患を治療する方法
EP4347018A1 (en) * 2021-05-28 2024-04-10 Eli Lilly and Company Anti-il-23p19 antibody regulation of genes involved in ulcerative colitis
WO2024110898A1 (en) * 2022-11-22 2024-05-30 Janssen Biotech, Inc. Method of treating ulcerative colitis with anti-il23 specific antibody
KR20250156783A (ko) 2023-03-10 2025-11-03 일라이 릴리 앤드 캄파니 궤양성 결장염을 치료하는 방법
TW202500185A (zh) * 2023-06-16 2025-01-01 大陸商信達生物製藥(蘇州)有限公司 重組抗白介素23p19亞基抗體在治療炎症性腸病中的用途

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HRP20130400T1 (en) * 2005-06-30 2013-06-30 Janssen Biotech, Inc. Anti-il-23 antibodies, compositions, methods and uses
DK2548577T3 (en) 2005-12-29 2017-03-13 Janssen Biotech Inc HUMAN ANTI-IL-23 ANTIBODIES, COMPOSITIONS, PROCEDURES AND APPLICATIONS
US8293883B2 (en) 2007-02-23 2012-10-23 Schering Corporation Engineered anti-IL-23P19 antibodies
US20110212104A1 (en) * 2008-11-03 2011-09-01 Schering Corporation Inflammatory bowel disease biomarkers and related methods of treatment
JO3244B1 (ar) 2009-10-26 2018-03-08 Amgen Inc بروتينات ربط مستضادات il – 23 البشرية
JP6126532B2 (ja) * 2010-11-04 2017-05-10 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 抗il−23抗体
JOP20140049B1 (ar) 2013-03-08 2021-08-17 Lilly Co Eli أجسام مضادة ترتبط بـ il-23
US20170002060A1 (en) * 2014-01-08 2017-01-05 Moderna Therapeutics, Inc. Polynucleotides for the in vivo production of antibodies
MX2020009265A (es) * 2018-03-05 2020-10-01 Janssen Biotech Inc Metodos para tratar la enfermedad de crohn con un anticuerpo especifico anti-il23.

Also Published As

Publication number Publication date
JP2023166388A (ja) 2023-11-21
EA202091989A1 (ru) 2021-01-13
AU2019243283A1 (en) 2020-09-24
IL312807A (en) 2024-07-01
CN111936165A (zh) 2020-11-13
WO2019191464A1 (en) 2019-10-03
IL277514B2 (en) 2024-11-01
TWI744617B (zh) 2021-11-01
MY202368A (en) 2024-04-24
BR112020018099A2 (pt) 2020-12-22
PT3773715T (pt) 2024-05-27
US12152072B2 (en) 2024-11-26
AU2019243283C1 (en) 2024-05-02
SI3773715T1 (sl) 2024-06-28
LT3773715T (lt) 2024-06-25
PL3773715T3 (pl) 2024-08-19
JP7571225B2 (ja) 2024-10-22
TW202206104A (zh) 2022-02-16
KR20200128101A (ko) 2020-11-11
EP4327866A3 (en) 2024-03-20
NZ767902A (en) 2024-05-31
AU2019243283B2 (en) 2023-07-27
TWI837532B (zh) 2024-04-01
JP2022169562A (ja) 2022-11-09
AU2023248103A1 (en) 2023-11-09
ES2983809T3 (es) 2024-10-24
IL312807B1 (en) 2025-02-01
TW201946657A (zh) 2019-12-16
HRP20240904T1 (hr) 2024-10-11
UA128578C2 (uk) 2024-08-21
EP4327866A2 (en) 2024-02-28
EP4327866B1 (en) 2025-12-10
SG11202009526RA (en) 2020-10-29
DK3773715T3 (da) 2024-05-27
ZA202005388B (en) 2025-05-28
IL277514A (en) 2020-11-30
EP3773715B1 (en) 2024-05-08
JP2021517156A (ja) 2021-07-15
US20250034243A1 (en) 2025-01-30
FI3773715T3 (fi) 2024-05-30
JP7331219B2 (ja) 2023-08-22
MA52216A (fr) 2021-02-17
IL277514B1 (en) 2024-07-01
MX2020010269A (es) 2020-11-06
HUE067445T2 (hu) 2024-10-28
JP2025020134A (ja) 2025-02-12
RS65661B1 (sr) 2024-07-31
KR102552693B1 (ko) 2023-07-07
JP7119114B2 (ja) 2022-08-16
MA52216B1 (fr) 2024-07-31
US20210032325A1 (en) 2021-02-04
EP3773715A1 (en) 2021-02-17
IL312807B2 (en) 2025-06-01
CA3095297A1 (en) 2019-10-03

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