MD372Z - Endoscopic method of hemostasis of bleeding ulcer in decompensated hepatic cirrhosis - Google Patents
Endoscopic method of hemostasis of bleeding ulcer in decompensated hepatic cirrhosis Download PDFInfo
- Publication number
- MD372Z MD372Z MDS20100203A MDS20100203A MD372Z MD 372 Z MD372 Z MD 372Z MD S20100203 A MDS20100203 A MD S20100203A MD S20100203 A MDS20100203 A MD S20100203A MD 372 Z MD372 Z MD 372Z
- Authority
- MD
- Moldova
- Prior art keywords
- ulcer
- hemostasis
- hepatic cirrhosis
- administered
- bleeding
- Prior art date
Links
- 208000025865 Ulcer Diseases 0.000 title abstract 4
- 231100000397 ulcer Toxicity 0.000 title abstract 4
- 230000000740 bleeding effect Effects 0.000 title abstract 2
- 208000019425 cirrhosis of liver Diseases 0.000 title abstract 2
- 230000023597 hemostasis Effects 0.000 title abstract 2
- UCTWMZQNUQWSLP-UHFFFAOYSA-N adrenaline Chemical compound CNCC(O)C1=CC=C(O)C(O)=C1 UCTWMZQNUQWSLP-UHFFFAOYSA-N 0.000 abstract 2
- 229920000642 polymer Polymers 0.000 abstract 2
- 108010039627 Aprotinin Proteins 0.000 abstract 1
- UXVMQQNJUSDDNG-UHFFFAOYSA-L Calcium chloride Chemical compound [Cl-].[Cl-].[Ca+2] UXVMQQNJUSDDNG-UHFFFAOYSA-L 0.000 abstract 1
- 108010049003 Fibrinogen Proteins 0.000 abstract 1
- 102000008946 Fibrinogen Human genes 0.000 abstract 1
- 206010017826 Gastric ulcer haemorrhage Diseases 0.000 abstract 1
- 208000032843 Hemorrhage Diseases 0.000 abstract 1
- 108090000190 Thrombin Proteins 0.000 abstract 1
- 229960004405 aprotinin Drugs 0.000 abstract 1
- 229910001628 calcium chloride Inorganic materials 0.000 abstract 1
- 239000001110 calcium chloride Substances 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229940012952 fibrinogen Drugs 0.000 abstract 1
- ZPNFWUPYTFPOJU-LPYSRVMUSA-N iniprol Chemical compound C([C@H]1C(=O)NCC(=O)NCC(=O)N[C@H]2CSSC[C@H]3C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H](C(N[C@H](C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC=4C=CC(O)=CC=4)C(=O)N[C@@H](CC=4C=CC=CC=4)C(=O)N[C@@H](CC=4C=CC(O)=CC=4)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CSSC[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC=4C=CC=CC=4)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(N)=N)NC2=O)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CSSC[C@H](NC(=O)[C@H](CC=2C=CC=CC=2)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H]2N(CCC2)C(=O)[C@@H](N)CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(O)=O)C(=O)N2[C@@H](CCC2)C(=O)N2[C@@H](CCC2)C(=O)N[C@@H](CC=2C=CC(O)=CC=2)C(=O)N[C@@H]([C@@H](C)O)C(=O)NCC(=O)N2[C@@H](CCC2)C(=O)N3)C(=O)NCC(=O)NCC(=O)N[C@@H](C)C(O)=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@H](C(=O)N[C@@H](CC=2C=CC=CC=2)C(=O)N[C@H](C(=O)N1)C(C)C)[C@@H](C)O)[C@@H](C)CC)=O)[C@@H](C)CC)C1=CC=C(O)C=C1 ZPNFWUPYTFPOJU-LPYSRVMUSA-N 0.000 abstract 1
- OELFLUMRDSZNSF-BRWVUGGUSA-N nateglinide Chemical compound C1C[C@@H](C(C)C)CC[C@@H]1C(=O)N[C@@H](C(O)=O)CC1=CC=CC=C1 OELFLUMRDSZNSF-BRWVUGGUSA-N 0.000 abstract 1
- 229960000698 nateglinide Drugs 0.000 abstract 1
- 229960004072 thrombin Drugs 0.000 abstract 1
Landscapes
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
The invention relates to medicine, in particular to hepatology and gastrology and can be used for endoscopic hemostasis of bleeding ulcer in decompensated hepatic cirrhosis.Summary of the invention consists in that it is performed the fibroesophagogastroduodenoscopy with identification of the bleeding gastric ulcer, then in the ulcer region and intravasal is administered a biological polymer consisting of two components, which are administered concomitantly in equal quantities, namely fibrinogen solution 15...30 mg/ml and a solution containing thrombin 25...100 IU/ml, calcium chloride 15...30 µmol/ml, adrenaline 0.1...0.3 mg/ml and aprotinin 250...1000 KIU/ml, the total quantity of polymer being of 4...12 ml, then in the ulcer region is administered 5.0 ml of glunate.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| MDS20100203A MD372Z (en) | 2010-11-30 | 2010-11-30 | Endoscopic method of hemostasis of bleeding ulcer in decompensated hepatic cirrhosis |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| MDS20100203A MD372Z (en) | 2010-11-30 | 2010-11-30 | Endoscopic method of hemostasis of bleeding ulcer in decompensated hepatic cirrhosis |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MD372Y MD372Y (en) | 2011-05-31 |
| MD372Z true MD372Z (en) | 2011-12-31 |
Family
ID=45815150
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MDS20100203A MD372Z (en) | 2010-11-30 | 2010-11-30 | Endoscopic method of hemostasis of bleeding ulcer in decompensated hepatic cirrhosis |
Country Status (1)
| Country | Link |
|---|---|
| MD (1) | MD372Z (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MD655Z (en) * | 2012-11-08 | 2014-03-31 | Ион КОРЧМАРУ | Method of wound hemostasis after necrectomy in patients with severe coagulopathies against decompensated hepatic cirrhosis |
| MD668Z (en) * | 2013-02-22 | 2014-03-31 | Георге АНГЕЛИЧ | Method for conservative hemostasis of gastroduodenal hemorrhages |
| MD880Z (en) * | 2014-05-21 | 2015-09-30 | Георге АНГЕЛИЧ | Method for mini-invasive treatment of massive hepatic metastases |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2483737C1 (en) * | 2012-03-15 | 2013-06-10 | Федеральное государственное бюджетное учреждение "Научный центр здоровья детей" Российской академии медицинских наук (ФГБУ "НЦЗД" РАМН) | Method for homeostatic disorder correction in children with hepatic hemangiomas |
| CN106620888A (en) * | 2016-08-25 | 2017-05-10 | 泰安市御翔医疗科技有限公司 | Preparation method of thrombin-controlled-release endoscopic-control hemostatic clip |
| CN106620890A (en) * | 2016-08-25 | 2017-05-10 | 泰安市御翔医疗科技有限公司 | Endoscopic hemostatic clips with thrombin sustained release function and method for preparing endoscopic hemostatic clips |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MD2328G2 (en) * | 2003-07-14 | 2004-07-31 | Константин ЦЫБЫРНЭ | Fibrinous adhesive and use thereof for endoscopic hemostasis of variceal hemorrhages in hepatic cirrhosis |
-
2010
- 2010-11-30 MD MDS20100203A patent/MD372Z/en not_active IP Right Cessation
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MD2328G2 (en) * | 2003-07-14 | 2004-07-31 | Константин ЦЫБЫРНЭ | Fibrinous adhesive and use thereof for endoscopic hemostasis of variceal hemorrhages in hepatic cirrhosis |
Non-Patent Citations (3)
| Title |
|---|
| Paquet K.J., Kuhn R. Prophylactic Endoscopic sclerotherapy in Patients with Liver Cirrhosis, Portal Hypertension and Esophageal Varices.- * |
| Чайченец Ф.С. Эндоскопический гемостаз клипированием при желудочно-кишечных кровотечениях. Автореф., Санкт-Петербург, * |
| Чайченец Ф.С. Эндоскопический гемостаз клипированием при желудочно-кишечных кровотечениях. Автореф., Санкт-Петербург, 2001, 19 с. * |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MD655Z (en) * | 2012-11-08 | 2014-03-31 | Ион КОРЧМАРУ | Method of wound hemostasis after necrectomy in patients with severe coagulopathies against decompensated hepatic cirrhosis |
| MD668Z (en) * | 2013-02-22 | 2014-03-31 | Георге АНГЕЛИЧ | Method for conservative hemostasis of gastroduodenal hemorrhages |
| MD880Z (en) * | 2014-05-21 | 2015-09-30 | Георге АНГЕЛИЧ | Method for mini-invasive treatment of massive hepatic metastases |
Also Published As
| Publication number | Publication date |
|---|---|
| MD372Y (en) | 2011-05-31 |
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| TK4Y | Erratum in official gazette with regard to short term patent |
Free format text: CHANGE IN INID 57 |
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| KA4Y | Short-term patent lapsed due to non-payment of fees (with right of restoration) | ||
| MM4Y | Short-term patent definitely lapsed due to non-payment of fees |