MD369Z - Method for predicting the risk of recurrence or malignization of precancerous process of the neck of uterus - Google Patents
Method for predicting the risk of recurrence or malignization of precancerous process of the neck of uterusInfo
- Publication number
- MD369Z MD369Z MDS20110007A MDS20110007A MD369Z MD 369 Z MD369 Z MD 369Z MD S20110007 A MDS20110007 A MD S20110007A MD S20110007 A MDS20110007 A MD S20110007A MD 369 Z MD369 Z MD 369Z
- Authority
- MD
- Moldova
- Prior art keywords
- malignization
- recurrence
- risk
- uterus
- neck
- Prior art date
Links
Landscapes
- Investigating Or Analysing Biological Materials (AREA)
Abstract
The invention relates to medicine, particularly to oncologic morphopathology and can be used for predicting the risk of recurrence or malignization of precancerous process of the neck of uterus using the immunologic double staining with antibodies anti-CD105 and anti-Ki67.Summary of the invention consists in the fact that after ionization of precancerous process of the neck of uterus there are prepared histological sections from biopsies of a thickness of 3 µm, they are stained with hematoxylin-eosin, afterwards there are carried out the reactions of immune staining with the antibody anti-CD105, clone SN6h, with staining in brown of the activated vascular endothelium, then with the antibody anti-Ki67, clone MIB1, with staining in red of the nuclei of endothelial cells and if it is determined 0…4 vessels with positive reaction to both antibodies, it is predicted a minimal risk of recurrence or malignization of precancerous process, and if it is determined more than 4 vessels, it is predicted an increased risk of recurrence or malignization of precancerous process.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
MDS20110007A MD369Z (en) | 2011-01-03 | 2011-01-03 | Method for predicting the risk of recurrence or malignization of precancerous process of the neck of uterus |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
MDS20110007A MD369Z (en) | 2011-01-03 | 2011-01-03 | Method for predicting the risk of recurrence or malignization of precancerous process of the neck of uterus |
Publications (2)
Publication Number | Publication Date |
---|---|
MD369Y MD369Y (en) | 2011-05-31 |
MD369Z true MD369Z (en) | 2011-12-31 |
Family
ID=45815147
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MDS20110007A MD369Z (en) | 2011-01-03 | 2011-01-03 | Method for predicting the risk of recurrence or malignization of precancerous process of the neck of uterus |
Country Status (1)
Country | Link |
---|---|
MD (1) | MD369Z (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
MD726Z (en) * | 2013-07-23 | 2014-08-31 | Адриан КИШКА | Method for prognosticating the evolution of gastric precancerous states in men |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
MD2653G2 (en) * | 2003-07-25 | 2005-09-30 | Институт Генетики И Физиологии Растений Академии Наук Молдовы | Process for tobacco cultivation |
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2011
- 2011-01-03 MD MDS20110007A patent/MD369Z/en not_active IP Right Cessation
Non-Patent Citations (9)
Title |
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Davidson B., Goldberg I., Kopolovic J. Angiogenesis in uterine cervical intraepithelial neoplasia and squamous cell carcinoma: an * |
Davidson B., Goldberg I., Kopolovic J. Angiogenesis in uterine cervical intraepithelial neoplasia and squamous cell carcinoma: an immunohistochemical study. Int J. Gynecol. Pathol., 1997, № 16, p. 335-338 * |
evaluating angiogenesis in cervical cancer. Pathol. Res. Pract., 2005, № 201, p. 34, 313-318 * |
Graflund M., Sorbe B., Hussein A., Bryne M., Karlsson M. The prognostic value of histopathologic grading parameters and microvessel density in * |
Graflund M., Sorbe B., Hussein A., Bryne M., Karlsson M. The prognostic value of histopathologic grading parameters and microvessel density in patients with early squamous cell carcinoma of the uterine cervix. Int J. Gynecol. Cancer, 2002, №12, p. 32-41 * |
immunohistochemical study. Int J. Gynecol. Pathol., 1997, № 16, p. 335-338 * |
patients with early squamous cell carcinoma of the uterine cervix. Int J. Gynecol. Cancer, 2002, №12, p. 32-41 * |
Vieira S.C., Silva B.B., Pinto G.A., Vassallo J., Moraes N.G., Santana J.O., Santos L.G., Carvasan G.A., Zeferino L.C. CD34 as a marker for * |
Vieira S.C., Silva B.B., Pinto G.A., Vassallo J., Moraes N.G., Santana J.O., Santos L.G., Carvasan G.A., Zeferino L.C. CD34 as a marker for evaluating angiogenesis in cervical cancer. Pathol. Res. Pract., 2005, № 201, p. 34, 313-318 * |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
MD726Z (en) * | 2013-07-23 | 2014-08-31 | Адриан КИШКА | Method for prognosticating the evolution of gastric precancerous states in men |
Also Published As
Publication number | Publication date |
---|---|
MD369Y (en) | 2011-05-31 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
KA4Y | Short-term patent lapsed due to non-payment of fees (with right of restoration) | ||
MM4Y | Short-term patent definitely lapsed due to non-payment of fees |