MD357Y - Method for predicting the risk of hematogenic metastasis after treatment of neoplasia of the neck of uterus - Google Patents

Method for predicting the risk of hematogenic metastasis after treatment of neoplasia of the neck of uterus

Info

Publication number
MD357Y
MD357Y MDS20110006A MDS20110006A MD357Y MD 357 Y MD357 Y MD 357Y MD S20110006 A MDS20110006 A MD S20110006A MD S20110006 A MDS20110006 A MD S20110006A MD 357 Y MD357 Y MD 357Y
Authority
MD
Moldova
Prior art keywords
risk
staining
hematogenic
metastasis
neoplasia
Prior art date
Application number
MDS20110006A
Other languages
Moldavian (mo)
Romanian (ro)
Inventor
Lilian Saptefrati
Anatol Cernii
Vitalie Mazuru
Lilian GUTU
Korina Kardanyuk
Eugen Ancuta
Codrina Ancuta
Lilian Şaptefraţi
Lilian Guţu
Corina Cardaniuc
Eugen Ancuţa
Codrina Ancuţa
Original Assignee
Lilian Saptefrati
Lilian Şaptefraţi
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilian Saptefrati, Lilian Şaptefraţi filed Critical Lilian Saptefrati
Priority to MDS20110006A priority Critical patent/MD357Z/en
Publication of MD357Y publication Critical patent/MD357Y/en
Publication of MD357Z publication Critical patent/MD357Z/en

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  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

The invention relates to medicine, in particular to oncologic morphopathology and can be used for predicting the risk of hematogenic metastasis after treatment of neoplasia of the neck of uterus using the immunological double staining with monoclonal antibodies anti-CD31 and anti-α smooth muscle actin.Summary of the invention consists in that there are prepared histological sections from biopsy materials of a thickness of 3 µm, they are stained with hematoxylin-eosin, and then there are carried out the reactions of immunological staining with monoclonal antibody anti-CD31, clone IC70A, with staining in brown of vascular endothelium, afterwards with the monoclonal antibody anti-α smooth muscle actin, clone 1A4, with staining in red of perivascular muscle cells and pericytes, on the basis of which is determined the number of immature vessels and if it is determined up to 5 immature vessels, it is predicted a minor risk of hematogenic metastasis, and if more than 5 immature vessels, it is predicted an increased risk of hematogenic metastasis.
MDS20110006A 2011-01-03 2011-01-03 Method for predicting the risk of hematogenic metastasis after treatment of neoplasia of the neck of uterus MD357Z (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
MDS20110006A MD357Z (en) 2011-01-03 2011-01-03 Method for predicting the risk of hematogenic metastasis after treatment of neoplasia of the neck of uterus

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
MDS20110006A MD357Z (en) 2011-01-03 2011-01-03 Method for predicting the risk of hematogenic metastasis after treatment of neoplasia of the neck of uterus

Publications (2)

Publication Number Publication Date
MD357Y true MD357Y (en) 2011-04-30
MD357Z MD357Z (en) 2011-11-30

Family

ID=45815103

Family Applications (1)

Application Number Title Priority Date Filing Date
MDS20110006A MD357Z (en) 2011-01-03 2011-01-03 Method for predicting the risk of hematogenic metastasis after treatment of neoplasia of the neck of uterus

Country Status (1)

Country Link
MD (1) MD357Z (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2489718C1 (en) * 2012-06-22 2013-08-10 Федеральное государственное бюджетное учреждение "Научно-исследовательский институт онкологии" Сибирского отделения Российской академии медицинских наук (ФГБУ "НИИ онкологии" СО РАМН) Method for prediction of onset of hematogenous metastases accompanying squamous cell lung cancer
  • 2011

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2489718C1 (en) * 2012-06-22 2013-08-10 Федеральное государственное бюджетное учреждение "Научно-исследовательский институт онкологии" Сибирского отделения Российской академии медицинских наук (ФГБУ "НИИ онкологии" СО РАМН) Method for prediction of onset of hematogenous metastases accompanying squamous cell lung cancer

Also Published As

Publication number Publication date
MD357Z (en) 2011-11-30

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Legal Events

Date Code Title Description
KA4Y Short-term patent lapsed due to non-payment of fees (with right of restoration)
MM4Y Short-term patent definitely lapsed due to non-payment of fees