MD3124B1 - Salicilidentiosemicarbazidati de cupru(II)care contin sulfanilamide - Google Patents

Salicilidentiosemicarbazidati de cupru(II)care contin sulfanilamide Download PDF

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Publication number
MD3124B1
MD3124B1 MDA20050150A MD20050150A MD3124B1 MD 3124 B1 MD3124 B1 MD 3124B1 MD A20050150 A MDA20050150 A MD A20050150A MD 20050150 A MD20050150 A MD 20050150A MD 3124 B1 MD3124 B1 MD 3124B1
Authority
MD
Moldova
Prior art keywords
copper
medicine
salicylidentesemicarbazidates
viii
vii
Prior art date
Application number
MDA20050150A
Other languages
English (en)
Other versions
MD3124C2 (ro
Inventor
Viorel Prisacari
Aurelian Gulea
Victor Tapcov
Svetlana Buraciova
Stela SPINU
Natalia Bejenari
Original Assignee
Universitatea De Stat De Medicina Si Farmacie "Nicolae Testemitanu" Din Republica Moldova
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Universitatea De Stat De Medicina Si Farmacie "Nicolae Testemitanu" Din Republica Moldova filed Critical Universitatea De Stat De Medicina Si Farmacie "Nicolae Testemitanu" Din Republica Moldova
Priority to MDA20050150A priority Critical patent/MD3124C2/ro
Publication of MD3124B1 publication Critical patent/MD3124B1/ro
Publication of MD3124C2 publication Critical patent/MD3124C2/ro

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Inventia se refera la chimie si medicina, si anume la sinteza unui sir de complecsi interni de cupru biologic activi din clasa tiosemicarbazidatilor metalelor de tranzitie si poate fi aplicata in medicina si in medicina veterinara. Esenta inventiei consta in aceea ca in calitate de preparate antimicrobiene se propun salicilidentiosemicarbazidatii de cupru(II) care contin sulfanilamide cu formula:unde X = H (I - VI, VIII - XI), Br(VII) ; R = H(I - VII), C6H5- (VIII - XI) ; Rezultatul inventiei consta in sinteza compusilor I-XI, care au toxicitate joasa, manifesta activitate antimicrobiana fatade majoritatea microorganismelor, iar in cazul tulpinilor gram-pozitive manifesta activitate bacteriostatica si bactericida de 2...160 ori mai inaltain comparatie cu analogul lor structural.
MDA20050150A 2005-05-25 2005-05-25 Salicilidentiosemicarbazidaţi de cupru(II) care conţin sulfanilamide MD3124C2 (ro)

Priority Applications (1)

Application Number Priority Date Filing Date Title
MDA20050150A MD3124C2 (ro) 2005-05-25 2005-05-25 Salicilidentiosemicarbazidaţi de cupru(II) care conţin sulfanilamide

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
MDA20050150A MD3124C2 (ro) 2005-05-25 2005-05-25 Salicilidentiosemicarbazidaţi de cupru(II) care conţin sulfanilamide

Publications (2)

Publication Number Publication Date
MD3124B1 true MD3124B1 (ro) 2006-08-31
MD3124C2 MD3124C2 (ro) 2007-03-31

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ID=36992836

Family Applications (1)

Application Number Title Priority Date Filing Date
MDA20050150A MD3124C2 (ro) 2005-05-25 2005-05-25 Salicilidentiosemicarbazidaţi de cupru(II) care conţin sulfanilamide

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MD (1) MD3124C2 (ro)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MD4133C1 (ro) * 2010-07-19 2012-05-31 Государственный Университет Молд0 [(2-Carbamotioilhidrazon)propionato(2-)]-(4-aminobenzensulfamid)cupru, care manifestă activitate antimicrobiană faţă de bacteriile din genul Bacillus cereus
MD4179C1 (ro) * 2011-05-23 2013-02-28 Государственный Университет Молд0 Compuşi coordinativi ai cuprului(II), care conţin 4-feniltiosemicarbazona 2-formilpiridinei şi sulfanilamide, care manifestă activitate antimicrobiană faţă de bacteriile din specia Bacillus cereus
MD4252C1 (ro) * 2012-05-31 2014-05-31 Государственный Университет Молд0 Catena-(µ-nitrato)[µ-(2-hidroxibenziliden)-4-prop-2-en-1-iltiosemicarbazon-S]argint cu activitate antimicrobiană faţă de bacteriile Salmonella abony

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MD3995C2 (ro) * 2009-05-11 2010-07-31 Государственный Университет Молд0 Utilizare a di(µ-Ofenoxi)-di{[2-(4-aminobenzensulfamido)-5-etil-1,3,4-tiadiazol]-3,5-dibromosalicilidentiosemicarbazonato(-1)-cupru} în calitate de inhibitor al proliferării celulelor T-47D ale cancerului mamar
MD4112C1 (ro) * 2010-05-17 2011-12-31 Государственный Университет Молд0 Compuşi coordinativi ai cuprului cu 4-(dimetilfenil)-tiosemicarbazonele 2-formilpiridinei
MD4127C1 (ro) * 2010-10-06 2012-04-30 Государственный Университет Молд0 Utilizare a di(µ-S)-bis{cloro-[1-(piridin-2-il)etanon-4-metiltiosemicarbazonato(1-)]cupru} în calitate de substanţă cu activitate antimicrobiană faţă de Staphylococcus aureus

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MD2942C2 (ro) * 2004-04-27 2006-06-30 Государственный Медицинский И Фармацевтический Университет "Nicolae Testemitanu" Республики Молдова Di(µ-O)-bis(3,5-dibromsalicilidentiosemicarbazonatocupru)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MD4133C1 (ro) * 2010-07-19 2012-05-31 Государственный Университет Молд0 [(2-Carbamotioilhidrazon)propionato(2-)]-(4-aminobenzensulfamid)cupru, care manifestă activitate antimicrobiană faţă de bacteriile din genul Bacillus cereus
MD4179C1 (ro) * 2011-05-23 2013-02-28 Государственный Университет Молд0 Compuşi coordinativi ai cuprului(II), care conţin 4-feniltiosemicarbazona 2-formilpiridinei şi sulfanilamide, care manifestă activitate antimicrobiană faţă de bacteriile din specia Bacillus cereus
MD4252C1 (ro) * 2012-05-31 2014-05-31 Государственный Университет Молд0 Catena-(µ-nitrato)[µ-(2-hidroxibenziliden)-4-prop-2-en-1-iltiosemicarbazon-S]argint cu activitate antimicrobiană faţă de bacteriile Salmonella abony

Also Published As

Publication number Publication date
MD3124C2 (ro) 2007-03-31

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FG4A Patent for invention issued
KA4A Patent for invention lapsed due to non-payment of fees (with right of restoration)
MM4A Patent for invention definitely lapsed due to non-payment of fees