MD2985F1 - Process for isothiocyanatochalcone obtaining - Google Patents

Process for isothiocyanatochalcone obtaining Download PDF

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Publication number
MD2985F1
MD2985F1 MDA20040244A MD20040244A MD2985F1 MD 2985 F1 MD2985 F1 MD 2985F1 MD A20040244 A MDA20040244 A MD A20040244A MD 20040244 A MD20040244 A MD 20040244A MD 2985 F1 MD2985 F1 MD 2985F1
Authority
MD
Moldova
Prior art keywords
obtaining
isothiocyanatochalcone
isothiocyanatochalcones
dimethylthioureidochalcones
chalcones
Prior art date
Application number
MDA20040244A
Other languages
Romanian (ro)
Other versions
MD2985G2 (en
Inventor
Nicanor BARBA
Gheorghe LUCHITA
Alic Barba
Roman Vieru
Original Assignee
Universitatea De Stat Din Moldova
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Universitatea De Stat Din Moldova filed Critical Universitatea De Stat Din Moldova
Priority to MDA20040244A priority Critical patent/MD2985G2/en
Publication of MD2985F1 publication Critical patent/MD2985F1/en
Publication of MD2985G2 publication Critical patent/MD2985G2/en

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  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Cosmetics (AREA)

Abstract

Inventia se refera la procedeele de obtinere a izotiocianatochalconelor, care pot fi utilizate in calitate de precursori pentru sinteza unor chalcone de uz medicinal sau cosmetic. Procedeul revendicat include condensarea l,l-dimetil-3-(3- sau 4-acetilfenil)tioureelor cu aldehide aromatice substituite, cu obtinerea N,N-dimetiltioureidochalconelor care se dezamineaza intr-un solvent inert la incalzire cu acizi minerali (H2SO4, HCl in dioxan) sau cu anhidrida acetica (in benzen sau toluen), luati, respectiv, in raport echimolar.The invention relates to the processes for obtaining isothiocyanatochalcones, which can be used as precursors for the synthesis of chalcones for medicinal or cosmetic use. The claimed process includes condensation of 1, 1-dimethyl-3- (3- or 4-acetylphenyl) thiols with substituted aromatic aldehydes to obtain N, N-dimethylthioureidochalcones which are dissolved in an inert solvent on heating with mineral acids (H2SO4, HCl in dioxane) or with acetic anhydride (in benzene or toluene), taken respectively in equimolar ratio.

MDA20040244A 2004-10-04 2004-10-04 Process for isothiocyanatochalcone obtaining MD2985G2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
MDA20040244A MD2985G2 (en) 2004-10-04 2004-10-04 Process for isothiocyanatochalcone obtaining

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
MDA20040244A MD2985G2 (en) 2004-10-04 2004-10-04 Process for isothiocyanatochalcone obtaining

Publications (2)

Publication Number Publication Date
MD2985F1 true MD2985F1 (en) 2006-02-28
MD2985G2 MD2985G2 (en) 2006-10-31

Family

ID=36002229

Family Applications (1)

Application Number Title Priority Date Filing Date
MDA20040244A MD2985G2 (en) 2004-10-04 2004-10-04 Process for isothiocyanatochalcone obtaining

Country Status (1)

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MD (1) MD2985G2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MD4077C1 (en) * 2010-01-18 2011-07-31 Государственный Университет Молд0 Process for obtaining N, N-dimethylthioureidobenzoic acids

Also Published As

Publication number Publication date
MD2985G2 (en) 2006-10-31

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Legal Events

Date Code Title Description
FG4A Patent for invention issued
KA4A Patent for invention lapsed due to non-payment of fees (with right of restoration)
MM4A Patent for invention definitely lapsed due to non-payment of fees