MD2905G2 - Process for obtaining symmetrical N,N'-malonyl-bis-diamides of the aminobensoic acid esters - Google Patents
Process for obtaining symmetrical N,N'-malonyl-bis-diamides of the aminobensoic acid estersInfo
- Publication number
- MD2905G2 MD2905G2 MDA20040009A MD20040009A MD2905G2 MD 2905 G2 MD2905 G2 MD 2905G2 MD A20040009 A MDA20040009 A MD A20040009A MD 20040009 A MD20040009 A MD 20040009A MD 2905 G2 MD2905 G2 MD 2905G2
- Authority
- MD
- Moldova
- Prior art keywords
- aminobensoic
- diamides
- malonyl
- bis
- acid esters
- Prior art date
Links
Landscapes
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
The invention relates to processes for obtaining pharmacologically active compounds used in the medical practice for treatment of cardiovascular diseases.The process for obtaining symmetrical N,N'-malonyl-bis-diamides of the aminobensoic acid esters includes condensation of the malonic ester with the aminobensoic acids esters, in the molar ratio of 1:2, in inert solvent at the temperature of 170…215°C.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
MDA20040009A MD2905G2 (en) | 2003-12-29 | 2003-12-29 | Process for obtaining symmetrical N,N'-malonyl-bis-diamides of the aminobensoic acid esters |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
MDA20040009A MD2905G2 (en) | 2003-12-29 | 2003-12-29 | Process for obtaining symmetrical N,N'-malonyl-bis-diamides of the aminobensoic acid esters |
Publications (3)
Publication Number | Publication Date |
---|---|
MD20040009A MD20040009A (en) | 2005-08-31 |
MD2905F2 MD2905F2 (en) | 2005-11-30 |
MD2905G2 true MD2905G2 (en) | 2006-07-31 |
Family
ID=34859145
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MDA20040009A MD2905G2 (en) | 2003-12-29 | 2003-12-29 | Process for obtaining symmetrical N,N'-malonyl-bis-diamides of the aminobensoic acid esters |
Country Status (1)
Country | Link |
---|---|
MD (1) | MD2905G2 (en) |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SU207236A1 (en) * | Ф. Г. Шепель , Л. Б. Дашкевич | METHOD FOR PRODUCING SODIUM OR POTASSIUM SALTS OF N, N'-MALOHYL-BI-AMIHOBENCHENIC ACIDS |
-
2003
- 2003-12-29 MD MDA20040009A patent/MD2905G2/en not_active IP Right Cessation
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SU207236A1 (en) * | Ф. Г. Шепель , Л. Б. Дашкевич | METHOD FOR PRODUCING SODIUM OR POTASSIUM SALTS OF N, N'-MALOHYL-BI-AMIHOBENCHENIC ACIDS | ||
SU195441A1 (en) * | Ф. Г. Шепель , Н. К. Лисицина | METHOD OF OBTAINING CHLORANGIDRID MALC NEVER ACID! |
Non-Patent Citations (5)
Title |
---|
Дашкевич Л.Б., Куваев Е.Н. ЖОХ, 1961, т. 31, N 5, с. 1669-1671 * |
Заржевский Е.В. Автореф. к.м.н. Ленинград, 1991, с. 19 * |
Мельникова Т.А., Рыжова А.Ф. Фармакология и химия. Ленинград, 1965, с. 207 * |
Михайлов К.В. Автореф. к.м.н. С.-Петербург, 1993, с. 20 * |
Шепель Ф.Г., Баев О.М., Дашкевич Л.Б. ЖПХ, 1996, т. 69, N 6, с. 987-998 * |
Also Published As
Publication number | Publication date |
---|---|
MD20040009A (en) | 2005-08-31 |
MD2905F2 (en) | 2005-11-30 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG4A | Patent for invention issued | ||
KA4A | Patent for invention lapsed due to non-payment of fees (with right of restoration) | ||
MM4A | Patent for invention definitely lapsed due to non-payment of fees |