MD2851F1 - Inhibitor of human myeloid leukemia on base of asymmetric cobalt trichloroacetate dimer - Google Patents
Inhibitor of human myeloid leukemia on base of asymmetric cobalt trichloroacetate dimerInfo
- Publication number
- MD2851F1 MD2851F1 MDA20040199A MD20040199A MD2851F1 MD 2851 F1 MD2851 F1 MD 2851F1 MD A20040199 A MDA20040199 A MD A20040199A MD 20040199 A MD20040199 A MD 20040199A MD 2851 F1 MD2851 F1 MD 2851F1
- Authority
- MD
- Moldova
- Prior art keywords
- aqua
- cobalt
- trichloroacetate
- bis
- inhibitor
- Prior art date
Links
Landscapes
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Inventia se refera la aplicarea combinatiilor coordinative in medicina si anume la utilizarea (m-aqua)-bis(m-tricloracetato)-tri(aqua)cobalt-aqua-bis(tricloracetato)cobalt monohidrat in calitate de inhibitor al leucemiei umane mieloide. Esenta inventiei consta in aceea ca in calitate de inhibitor al leucemiei umane mieloide se revendica (m-aqua)-bis(m-tricloracetato)-tri(aqua)cobalt-aqua-bis(tricloracetato)cobalt monohidrat cu formula :Rezultatul inventiei consta in stabilirea la cunoscutul (m-aqua)-bis(m-tricloracetato)-tri(aqua)cobalt-aqua-bis(tricloracetato)cobalt monohidrat a activitatii anticanceroase, care depaseste de 1,25...1,35 ori caracteristicile analoage ale dimerilor trihidratului aquaetilendiamintetraacetatobismutatului(III) de 1,6-dinitrotetraamincobalt(III) si dihidratului etilendiamintetraacetatobismutatului(III) de oxalatotetraamincobalt(III) (analogului).The invention relates to the application of coordinative combinations in medicine, namely to the use (m-aqua)-bis (m-trichloroacetate) -tri (aqua) cobalt-aqua-bis (trichloracetate) cobalt monohydrate as an inhibitor of human myeloid leukemia. The essence of the invention is that as a human myeloid leukemia inhibitor it is claimed (m-aqua) -bis (m-trichloroacetate) -tri (aqua) cobalt-aqua-bis (trichloracetate) cobalt monohydrate of the formula: The result of the invention consists in establishing at known (m-aqua)-bis (m-trichloroacetate) -thi (aqua) cobalt-aqua-bis (trichloracetate) cobalt monohydrate of the anticancer activity, which exceeds 1.25 ... 1.35 times the analogous characteristics of dimers of the 1,6-dinitrotetraamincobalt (III) aquaethylenediaminetetraacetate acetate (III) and the oxalatotetraamincobalt (III) ethylenediaminetetraacetate (III) dihydrate (analog).
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
MDA20040199A MD2851G2 (en) | 2004-08-12 | 2004-08-12 | Inhibitor of human myeloid leukemia on base of asymmetric cobalt trichloroacetate dimer |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
MDA20040199A MD2851G2 (en) | 2004-08-12 | 2004-08-12 | Inhibitor of human myeloid leukemia on base of asymmetric cobalt trichloroacetate dimer |
Publications (2)
Publication Number | Publication Date |
---|---|
MD2851F1 true MD2851F1 (en) | 2005-09-30 |
MD2851G2 MD2851G2 (en) | 2006-04-30 |
Family
ID=35057542
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MDA20040199A MD2851G2 (en) | 2004-08-12 | 2004-08-12 | Inhibitor of human myeloid leukemia on base of asymmetric cobalt trichloroacetate dimer |
Country Status (1)
Country | Link |
---|---|
MD (1) | MD2851G2 (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
MD3098G2 (en) * | 2006-01-03 | 2007-02-28 | Государственный Университет Молд0 | Dihydrate of di( -Ophenoxy)-di[N-(2-oxy-1-benzal)-N1- -oxyfuralhydrazine(2-)copper] with properties of inhibitor of the human myeloid leukemia |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
MD4215C1 (en) * | 2012-07-09 | 2013-11-30 | Государственный Университет Молд0 | Inhibitor of human myeloid leukemia based on N-(4-(5-(pyridin-2-yl)-4,5-dihydro-1H-pyrazol-3-yl)phenyl)-2-(pyridin-2-ylmethylen)-hydrazinecarbothioamide |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
MD2786G2 (en) * | 2004-05-11 | 2006-02-28 | Государственный Университет Молд0 | Inhibitors of human myeloid leukemia on base of heteronuclear coordinative compounds of cobalt(III) and bismuth(III) |
-
2004
- 2004-08-12 MD MDA20040199A patent/MD2851G2/en not_active IP Right Cessation
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
MD3098G2 (en) * | 2006-01-03 | 2007-02-28 | Государственный Университет Молд0 | Dihydrate of di( -Ophenoxy)-di[N-(2-oxy-1-benzal)-N1- -oxyfuralhydrazine(2-)copper] with properties of inhibitor of the human myeloid leukemia |
Also Published As
Publication number | Publication date |
---|---|
MD2851G2 (en) | 2006-04-30 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
KA4A | Patent for invention lapsed due to non-payment of fees (with right of restoration) | ||
MM4A | Patent for invention definitely lapsed due to non-payment of fees |